Search Results - "Palmer, Gene"

Synthetic generation of influenza vaccine viruses for rapid response to pandemics by Dormitzer, Philip R, Suphaphiphat, Pirada, Gibson, Daniel G, Wentworth, David E, Stockwell, Timothy B, Algire, Mikkel A, Alperovich, Nina, Barro, Mario, Brown, David M, Craig, Stewart, Dattilo, Brian M, Denisova, Evgeniya A, De Souza, Ivna, Eickmann, Markus, Dugan, Vivien G, Ferrari, Annette, Gomila, Raul C, Han, Liqun, Judge, Casey, Mane, Sarthak, Matrosovich, Mikhail, Merryman, Chuck, Palladino, Giuseppe, Palmer, Gene A, Spencer, Terika, Strecker, Thomas, Trusheim, Heidi, Uhlendorff, Jennifer, Wen, Yingxia, Yee, Anthony C, Zaveri, Jayshree, Zhou, Bin, Becker, Stephan, Donabedian, Armen, Mason, Peter W, Glass, John I, Rappuoli, Rino, Venter, J Craig

“…During the 2009 H1N1 influenza pandemic, vaccines for the virus became available in large quantities only after human infections peaked. To accelerate vaccine…”
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Plant-expressed HA as a seasonal influenza vaccine candidate by Shoji, Yoko, Chichester, Jessica A, Bi, Hong, Musiychuk, Konstantin, de la Rosa, Patricia, Goldschmidt, Lauren, Horsey, April, Ugulava, Natalia, Palmer, Gene A, Mett, Vadim, Yusibov, Vidadi

“…Abstract Influenza is a globally important respiratory pathogen that causes a high degree of morbidity and mortality annually. Although current vaccines are…”
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The role of non-viral antigens in the cotton rat model of respiratory syncytial virus vaccine-enhanced disease by Shaw, Christine A, Galarneau, Jean-Rene, Bowenkamp, Kathryn E, Swanson, Kurt A, Palmer, Gene A, Palladino, Giuseppe, Markovits, Judit E, Valiante, Nicholas M, Dormitzer, Philip R, Otten, Gillis R

“…Highlights ► Investigated mechanism of FI-RSV-mediated vaccine-enhanced disease in cotton rats. ► Non-viral antigens in vaccine and challenge materials drive…”
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A plant-produced plague vaccine candidate confers protection to monkeys by Mett, Vadim, Lyons, Jarred, Musiychuk, Konstantin, Chichester, Jessica A, Brasil, Trevor, Couch, Ronald, Sherwood, Robert, Palmer, Gene A, Streatfield, Stephen J, Yusibov, Vidadi

“…Abstract Production of vaccine antigens in plants has received considerable attention over the last decade. However, despite many antigens being expressed in…”
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Immunogenicity of a subunit vaccine against Bacillus anthracis by Chichester, Jessica A, Musiychuk, Konstantin, de la Rosa, Patricia, Horsey, April, Stevenson, Natalie, Ugulava, Natalia, Rabindran, Shailaja, Palmer, Gene A, Mett, Vadim, Yusibov, Vidadi

“…Abstract The current approved vaccine against anthrax is based on protective antigen (PA) of Bacillus anthracis , requires six injections over an 18-month…”
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Neuroprotection by NMDA receptor antagonists in a variety of neuropathologies by Palmer, G C

“…Because of adverse reactions, early efforts to introduce high affinity competitive or use-dependent NMDA receptor antagonists into patients suffering from…”
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A plant‐produced influenza subunit vaccine protects ferrets against virus challenge by Mett, Vadim, Musiychuk, Konstantin, Bi, Hong, Farrance, Christine E., Horsey, April, Ugulava, Natalia, Shoji, Yoko, De La Rosa, Patricia, Palmer, Gene A., Rabindran, Shailaja, Streatfield, Stephen J., Boyers, Alison, Russell, Michael, Mann, Alex, Lambkin, Robert, Oxford, John S., Schild, Geoffrey C., Yusibov, Vidadi

“…Background  Influenza A viruses are of major concern for public health, causing worldwide epidemics associated with high morbidity and mortality. Vaccines are…”
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Hairy roots as a vaccine production and delivery system by Skarjinskaia, Marina, Ruby, Karen, Araujo, Adriana, Taylor, Karina, Gopalasamy-Raju, Vengadesan, Musiychuk, Konstantin, Chichester, Jessica A, Palmer, Gene A, de la Rosa, Patricia, Mett, Vadim, Ugulava, Natalia, Streatfield, Stephen J, Yusibov, Vidadi

“…Prevention of infectious diseases by vaccination is often limited because of the lack of safe, effective, and accessible vaccines. Traditional vaccines are…”
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An influenza N1 neuraminidase-specific monoclonal antibody with broad neuraminidase inhibition activity against H5N1 HPAI viruses by Shoji, Yoko, Chichester, Jessica A., Palmer, Gene A., Farrance, Christine E., Stevens, Robert, Stewart, Michelle, Goldschmidt, Lauren, Deyde, Varough, Gubareva, Larisa, Klimov, Alexander, Mett, Vadim, Yusibov, Vidadi

“…H5N1 avian influenza continues to be a potential pandemic threat. Several vaccine candidates based on potentially pandemic influenza strains and antiviral…”
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Antibody affinity maturation and respiratory syncytial virus disease by Dormitzer, Philip R, Shaw, Christine A, Otten, Gillis, Wack, Andreas, Palmer, Gene A, Mandl, Christian W, Mbow, M Lamine, Valiante, Nicholas

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Mutations at positions 186 and 194 in the HA gene of the 2009 H1N1 pandemic influenza virus improve replication in cell culture and eggs by Suphaphiphat, Pirada, Franti, Michael, Hekele, Armin, Lilja, Anders, Spencer, Terika, Settembre, Ethan, Palmer, Gene, Crotta, Stefania, Tuccino, Annunziata B, Keiner, Bjoern, Trusheim, Heidi, Balabanis, Kara, Sackal, Melissa, Rothfeder, Mithra, Mandl, Christian W, Dormitzer, Philip R, Mason, Peter W

“…Obtaining suitable seed viruses for influenza vaccines poses a challenge for public health authorities and manufacturers. We used reverse genetics to generate…”
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A Nonproliferating Parvovirus Vaccine Vector Elicits Sustained, Protective Humoral Immunity following a Single Intravenous or Intranasal Inoculation by PALMER, Gene A, BROGDON, Jennifer L, CONSTANT, Stephanie L, TATTERSALL, Peter

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Maturation of erythroid cells and erythroleukemia development are affected by the kinase activity of Lyn by TILBROOK, Peta A, PALMER, Gene A, SCHNEIDER-MERGENER, Jens, KRYSTAL, Gerald, KLINKEN, S. Peter, BITTORF, Thomas, MCCARTHY, David J, WRIGHT, Michael J, SARNA, Mohinder K, LINNEKIN, Diana, CULL, Vanessa S, WILLIAMS, James H, INGLEY, Evan

“…This study examined the impact of the tyrosine kinase Lyn on erythropoietin-induced intracellular signaling in erythroid cells. In J2E erythroleukemic cells,…”
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Differential regulation of SOCS genes in normal and transformed erythroid cells by SARNA, Mohinder K, INGLEY, Evan, ALEXANDER, Warren S, HILTON, Douglas J, STARRY, Robyn, WATOWICH, Stephanie S, BITTORF, Thomas, KLINKEN, S. Peter, TILBROOK, Peta A, BUSFIELD, Samantha J, CULL, Vanessa S, LEPERE, Winald, MCCARTHY, David J, WRIGHT, Michael J, PALMER, Gene A, CHAPPELL, David, SAYER, Melissa S

“…The SOCS family of genes are negative regulators of cytokine signalling with SOCS-1 displaying tumor suppressor activity. SOCS-1, CIS and SOCS-3 have been…”
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Rat middle cerebral artery occlusion: Correlations between histopathology, T2-weighted magnetic resonance imaging, and behavioral indices by Peeling, James, Corbett, Dale, Del Bigio, Marc R., Hudzik, Thomas J., Campbell, T.Mark, Palmer, Gene C.

“…During attempts to develop the intraluminal suture model of transient middle cerebral artery occlusion (MCAO) in the Sprague Dawley strain of rats, we noticed…”
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Antianxiety properties of the angiotensin II antagonist, DUP 753, in the rat using the elevated plus-maze by Kaiser, F C, Palmer, G C, Wallace, A V, Carr, R D, Fraser-Rae, L, Hallam, C

“…The angiotensin II receptor antagonist, DUP 753 (Losartan), was compared with diazepam for antianxiety properties in the rat using the elevated plus-maze. Oral…”
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Remacemide hydrochloride and ARL 15896AR lack abuse potential: additional differences from other uncompetitive NMDA antagonists by Hudzik, T J, Freedman, L, Palmer, G C

“…This study was designed to determine the possible abuse liability and phencyclidine-like effects of the low-affinity uncompetitive N-methyl-D-aspartate (NMDA)…”
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Acute heat stress model of seizures in weanling rats: Influence of prototypic anti-seizure compounds by Palmer, Gene C, Borrelli, Alfonso R, Hudzik, Thomas J, Sparber, Sheldon

“…The present study tested the therapeutic potential for prototype anti-epilepsy drugs using an animal model of infantile febrile seizures. The model consisted…”
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Efficacy of AR-R15896AR in the rat monofilament model of transient middle cerebral artery occlusion by Bialobok, Paul, Cregan, Edward F., Sydserff, Simon G., Eisman, Mark S., Miller, Jerry A., Cross, Alan J., Simmons, Roy, Gendron, Patricia, McCarthy, Dennis J., Palmer, Gene C.

“…The monofilament technique of transient middle cerebral artery occlusion (MCAO) was used in 3 separate studies to evaluate the efficacy of the low-affinity,…”
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Kainic acid and 4-aminopyridine seizure models in mice: evaluation of efficacy of anti-epileptic agents and calcium antagonists by Cramer, C L, Stagnitto, M L, Knowles, M A, Palmer, G C

“…Seizures may be induced in mice in response to stimulation of subtypes of glutamate receptors by kainic acid or inhibition of certain voltage-dependent…”
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