Search Results - "Palmer, David J"
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Characterization of an α-Glucosidase Enzyme Conserved in Gardnerella spp. Isolated from the Human Vaginal Microbiome
Published in Journal of bacteriology (09-08-2021)“…spp. in the vaginal microbiome are associated with bacterial vaginosis, in which a lactobacillus-dominated community is replaced with mixed bacteria, including…”
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Staphylococcus aureus haem biosynthesis and acquisition pathways are linked through haem monooxygenase IsdG
Published in Molecular microbiology (01-08-2018)“…Summary Haem is an essential cofactor in central metabolic pathways in the vast majority of living systems. Prokaryotes acquire haem via haem biosynthesis…”
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Simultaneous Measurement of Glucose-6-phosphate 3‑Dehydrogenase (NtdC) Catalysis and the Nonenzymatic Reaction of Its Product: Kinetics and Isotope Effects on the First Step in Kanosamine Biosynthesis
Published in Biochemistry (Easton) (11-04-2017)“…Glucose-6-phosphate 3-dehydrogenase (NtdC) is an NAD-dependent oxidoreductase encoded in the NTD operon of Bacillus subtilis. The oxidation of glucose…”
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Assessing the Broader Value of Planted Forests to Inform Forest Management Decisions
Published in Forests (01-06-2021)“…This study highlights the importance of incorporating objectively quantified, non-market environmental values (such as avoided erosion and carbon…”
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Soil Bacterial Communities Exhibit Strong Biogeographic Patterns at Fine Taxonomic Resolution
Published in mSystems (21-07-2020)“…Bacteria have been inferred to exhibit relatively weak biogeographic patterns. To what extent such findings reflect true biological phenomena or methodological…”
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Options for reducing uncertainty in impact classification for alien species
Published in Ecosphere (Washington, D.C) (01-04-2021)“…Impact assessment is an important and cost‐effective tool for assisting in the identification and prioritization of invasive alien species. With the number of…”
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Dihydrodipicolinate Synthase from Campylobacter jejuni: Kinetic Mechanism of Cooperative Allosteric Inhibition and Inhibitor-Induced Substrate Cooperativity
Published in Biochemistry (Easton) (13-08-2013)“…Dihydrodipicolinate synthase (DHDPS), an enzyme of the meso-diaminopimelate pathway of lysine biosynthesis, is essential for bacterial growth and is considered…”
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Identification of Interactions between Abscisic Acid and Ribulose-1,5-Bisphosphate Carboxylase/Oxygenase
Published in PloS one (21-07-2015)“…Abscisic acid ((+)-ABA) is a phytohormone involved in the modulation of developmental processes and stress responses in plants. A chemical proteomics approach…”
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A Previously Unrecognized Kanosamine Biosynthesis Pathway in Bacillus subtilis
Published in Journal of the American Chemical Society (24-04-2013)“…The ntd operon in Bacillus subtilis is essential for biosynthesis of 3,3′-neotrehalosadiamine (NTD), an unusual nonreducing disaccharide reported to have…”
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Linking climate suitability, spread rates and host impact when estimating the potential costs of invasive pests
Published in PloS one (06-02-2013)“…Notes how biosecurity agencies need to be able to estimate the potential for each invasive alien species (IAS) to create negative impacts, so that relative and…”
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Substrate Substitution in Kanosamine Biosynthesis Using Phosphonates and Phosphite Rescue
Published in Biochemistry (Easton) (22-06-2021)“…Kanosamine is an antibiotic and antifungal compound synthesized from glucose 6-phosphate (G6P) in Bacillus subtilis by the action of three enzymes: NtdC, which…”
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Tyrosine 110 Plays a Critical Role in Regulating the Allosteric Inhibition of Campylobacter jejuni Dihydrodipicolinate Synthase by Lysine
Published in Biochemistry (Easton) (02-12-2014)“…Dihydrodipicolinate synthase (DHDPS), an enzyme found in most bacteria and plants, controls a critical step in the biosynthesis of l-lysine and…”
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Characterization of bovine seminal plasma by proteomics
Published in Proteomics (Weinheim) (01-11-2006)“…Previous investigations of bovine seminal plasma (BSP) have revealed the identities of the three major proteins, BSP‐PDC109, BSP‐A3 and BSP‐30 kDa, which…”
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Biotechnological Advances in Bacterial Microcompartment Technology
Published in Trends in biotechnology (Regular ed.) (01-03-2019)“…Bacterial microcompartments (BMCs) represent proteinaceous macromolecular nanobioreactors that are found in a broad range of bacteria, and which are associated…”
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Structural investigation of myo-inositol dehydrogenase from Bacillus subtilis: implications for catalytic mechanism and inositol dehydrogenase subfamily classification
Published in Biochemical journal (01-12-2010)“…Inositol dehydrogenase from Bacillus subtilis (BsIDH) is a NAD+-dependent enzyme that catalyses the oxidation of the axial hydroxy group of myo-inositol to…”
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Reducing topical drug waste in ophthalmic surgery: multisociety position paper
Published in Journal of cataract and refractive surgery (01-09-2022)“…This position article on reducing topical drug waste with ophthalmic surgery was written by the Ophthalmic Instrument Cleaning and Sterilization Task Force,…”
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Carbocyclic Substrate Analogues Reveal Kanosamine Biosynthesis Begins with the α‑Anomer of Glucose 6‑Phosphate
Published in ACS chemical biology (21-08-2020)“…NtdC is an NAD-dependent dehydrogenase that catalyzes the conversion of glucose 6-phosphate (G6P) to 3-oxo-glucose 6-phosphate (3oG6P), the first step in…”
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Improving quality of care and reducing topical medication operating room waste
Published in Journal of cataract and refractive surgery (01-08-2020)Get full text
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Evidence of Allosteric Enzyme Regulation via Changes in Conformational Dynamics: A Hydrogen/Deuterium Exchange Investigation of Dihydrodipicolinate Synthase
Published in Biochemistry (Easton) (27-09-2016)“…Dihydrodipicolinate synthase is a tetrameric enzyme of the diaminopimelate pathway in bacteria and plants. The protein catalyzes the condensation of pyruvate…”
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Revaluating forest drought experiments according to future precipitation patterns, ecosystem carbon and decomposition rate responses: A meta-analysis
Published in Ambio (01-05-2022)“…Moisture availability is a strong determinant of decomposition rates in forests worldwide. Climate models suggest that many terrestrial ecosystems are at risk…”
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