Search Results - "Palma, M. U."

A Homozygous CARD9 Mutation in a Brazilian Patient with Deep Dermatophytosis by Grumach, Anete S., de Queiroz-Telles, Flavio, Migaud, Mélanie, Lanternier, Fanny, Filho, Nelson Rosario, Palma, Sandra M. U., Constantino-Silva, Rosemeire Navickas, Casanova, Jean Laurent, Puel, Anne

“…Deep dermatophytosis has been described in HIV and immunosuppressed patients. Recently, CARD9 (caspase recruitment domain-containing protein 9) deficiency has…”
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Protein Aggregation/Crystallization and Minor Structural Changes: Universal versus Specific Aspects by Pullara, F., Emanuele, A., Palma-Vittorelli, M.B., Palma, M.U.

“…Protein association covers wide interests in biophysics, protein science, and biotechnologies, and it is often viewed as governed by conformation details. More…”
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Protein crystallization: universal thermodynamic vs. specific effects of PEG by Pullara, F, Emanuele, A, Palma-Vittorelli, M B, Palma, M U

“…The interest of nucleation of protein crystals and aggregates (including oligomerization) spans from basic physics theory all the way to biophysics,…”
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The role of pH on instability and aggregation of sickle hemoglobin solutions by Manno, M., San Biagio, P. L., Palma, M. U.

“…Understanding the physical basis of protein aggregation covers strong physical and biomedical interests. Sickle hemoglobin (HbS) is a point‐mutant form of…”
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Irreversible formation of intermediate BSA oligomers requires and induces conformational changes by Vaiana, S.M., Emanuele, A., Palma-Vittorelli, M.B., Palma, M.U.

“…Understanding the relation between protein conformational changes and aggregation, and the physical mechanisms leading to such processes, is of primary…”
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Time scale of protein aggregation dictated by liquid-liquid demixing by Vaiana, S.M., Palma-Vittorelli, M.B., Palma, M.U.

“…The growing impact of protein aggregation pathologies, together with the current high need for extensive information on protein structures are focusing much…”
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Lysozyme crystallization rates controlled by anomalous fluctuations by Pullara, F., Emanuele, A., Palma-Vittorelli, M.B., Palma, M.U.

“…Nucleation of protein aggregates and crystals is a process activated by statistical fluctuations of concentration. Nucleation rates may change by several…”
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Interacting processes in protein coagulation by San Biagio, P.L., Martorana, V., Emanuele, A., Vaiana, S.M., Manno, M., Bulone, D., Palma-Vittorelli, M.B., Palma, M.U.

“…A strong interest is currently focused on protein self‐association and deposit. This usually involves conformational changes of the entire protein or of a…”
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Self-assembly of biopolymeric structures below the threshold of random cross-link percolation by San Biagio, P.L., Bulone, D., Emanuele, A., Palma, M.U.

“…Self-assembly of extended structures via cross-linking of individual biomolecules often occurs in solutions at concentrations well below the estimated…”
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Spinodal lines and Flory-Huggins free-energies for solutions of human hemoglobins HbS and HbA by San Biagio, P.L., Palma, M.U.

“…Gelation of deoxygenated solutions of sickle-cell human Hemoglobin (HbS) is of high theoretical interest and it has serious pathological consequences. For this…”
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Spontaneous symmetry-breaking pathways: time-resolved study of agarose gelation by San Biagio, P.L., Bulone, D., Emanuele, A., Palma-Vittorelli, M.B., Palma, M.U.

“…Extensive time-resolved studies of self-assembly of agarose gels, performed with the use of a variety of techniques allowed identification of the initial break…”
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Interaction of explicit solvent with hydrophobic/philic/charged residues of a protein: Residue character vs. conformational context by Martorana, V., Corongiu, G., Palma, M.U.

“…Molecular dynamics simulations of model solutes in explicit molecular water have recently elicited novel aspects of the strong nonpair additivity of the…”
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The role of solvent in protein folding and in aggregation by Vaiana, S M, Manno, M, Emanuele, A, Palma-Vittorelli, M B, Palma, M U

“…We discuss features of the effect of solvent on protein folding andaggregation, highlighting the physics related to the particulate nature and the peculiar…”
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Collective properties of hydration: long range and specificity of hydrophobic interactions by Martorana, V., Bulone, D., San Biagio, P.L., Palma-Vittorelli, M.B., Palma, M.U.

“…We report results of molecular dynamics (MD) simulations of composite model solutes in explicit molecular water solvent, eliciting novel aspects of the…”
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Self-assembly of bioelastomeric structures from solutions: mean-field critical behavior and Flory-Huggins free energy of interactions by Sciortino, F, Prasad, K U, Urry, D W, Palma, M U

“…Elastic and quasi-elastic light scattering studies were performed on aqueous solutions of poly(Val-Pro-Gly-Gly), a representative synthetic bioelastomer that…”
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Hypogammaglobulinemia: a diagnosis that must not be overlooked by Pimenta, F.M.C.A, Palma, S.M.U, Constantino-Silva, R.N, Grumach, A.S

“…Humoral immunological defects are frequent and important causes of hypogammaglobulinemia, leading to recurrent infections, autoimmunity, allergies, and…”
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Hereditary angioedema with C1 inhibitor (C1-INH) deficit: the strength of recognition (51 cases) by Fragnan, N T M L, Tolentino, A L N, Borba, G B, Oliveira, A C, Simões, J A, Palma, S M U, Constantino-Silva, R N, Grumach, A S

“…Hereditary angioedema (HAE) is a rare autosomal dominant disease due to C1 esterase inhibitor deficiency (C1-INH). The disease is characterized by subcutaneous…”
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Solvent-Induced Free Energy Landscape and Solute-Solvent Dynamic Coupling in a Multielement Solute by San Biagio, P.L., Martorana, V., Bulone, D., Palma-Vittorelli, M.B., Palma, M.U.

“…Molecular dynamics simulations using a simple multielement model solute with internal degrees of freedom and accounting for solvent-induced interactions to all…”
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Self-assembly of a bioelastomeric structure: solution dynamics and the spinodal and coacervation lines by Sciortino, F, Urry, D W, Palma, M U, Prasad, K U

“…The stability, metastability, and instability regions of aqueous solutions of a representative synthetic bioelastomeric polymer, poly (Val-Pro-Gly-Val-Gly),…”
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Physics and biophysics of solvent induced forces: hydrophobic interactions and context-dependent hydration by San Biagio, P. L., Bulone, D., Martorana, V., Palma-Vittorelli, M. B., Palma, M. U.

“…Solvent induced forces (SIFs) among solutes derive from solvent structural modification due to solutes, and consequent thermodynamic drive towards minimization…”
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