Search Results - "Palma, Ernesto"
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Antimicrobial Resistance in Veterinary Medicine: An Overview
Published in International journal of molecular sciences (11-03-2020)“…Antimicrobial resistance (AMR) represents one of the most important human- and animal health-threatening issues worldwide. Bacterial capability to face…”
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From birth to death: A role for reactive oxygen species in neuronal development
Published in Seminars in cell & developmental biology (01-08-2018)“…Historically, ROS have been considered toxic molecules, especially when their intracellular concentration reaches high values. However, physiological levels of…”
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Modulation of Nitric Oxide Synthases by Oxidized LDLs: Role in Vascular Inflammation and Atherosclerosis Development
Published in International journal of molecular sciences (04-07-2019)“…The maintenance of physiological levels of nitric oxide (NO) produced by eNOS represents a key element for vascular endothelial homeostasis. On the other hand,…”
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The Contribution of Gut Microbiota-Brain Axis in the Development of Brain Disorders
Published in Frontiers in neuroscience (23-03-2021)“…Different bacterial families colonize most mucosal tissues in the human organism such as the skin, mouth, vagina, respiratory, and gastrointestinal districts…”
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Enjoy your journey: the bergamot polyphenols from the tree to the cell metabolism
Published in Journal of translational medicine (04-11-2021)“…Keywords: Bergamot, Cell metabolism, Flavonoids, Antioxidant, Dyslipidemia, Metabolic diseases…”
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Antioxidant modulation of sirtuin 3 during acute inflammatory pain: The ROS control
Published in Pharmacological research (01-07-2020)“…[Display omitted] Oxidative stress induced post-translational protein modifications are associated with the development of inflammatory hypersensitivities. At…”
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The Anti-Inflammatory and Antioxidant Properties of n-3 PUFAs: Their Role in Cardiovascular Protection
Published in Biomedicines (25-08-2020)“…Polyunsaturated fatty acids (n-3 PUFAs) are long-chain polyunsaturated fatty acids with 18, 20 or 22 carbon atoms, which have been found able to counteract…”
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Antiseizure Medications in Alzheimer’s Disease from Preclinical to Clinical Evidence
Published in International journal of molecular sciences (01-08-2023)“…Alzheimer’s disease (AD) and epilepsy are common neurological disorders in the elderly. A bi-directional link between these neurological diseases has been…”
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Antileishmanial Activity of Amphotericin B-loaded-PLGA Nanoparticles: An Overview
Published in Materials (09-07-2018)“…In recent decades, nanotechnology has made phenomenal strides in the pharmaceutical field, favouring the improvement of the biopharmaceutical properties of…”
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10
A Feed-Forward Mechanism Involving the NOX Complex and RyR-Mediated Ca2+ Release During Axonal Specification
Published in The Journal of neuroscience (26-10-2016)“…Physiological levels of ROS support neurite outgrowth and axonal specification, but the mechanisms by which ROS are able to shape neurons remain unknown. Ca ,…”
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The "Frail" Brain Blood Barrier in Neurodegenerative Diseases: Role of Early Disruption of Endothelial Cell-to-Cell Connections
Published in International journal of molecular sciences (10-09-2018)“…The main neurovascular unit of the Blood Brain Barrier (BBB) consists of a cellular component, which includes endothelial cells, astrocytes, pericytes,…”
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Bergamot Polyphenols Improve Dyslipidemia and Pathophysiological Features in a Mouse Model of Non-Alcoholic Fatty Liver Disease
Published in Scientific reports (13-02-2020)“…There is a need for continued drug development for nonalcoholic steatohepatitis (NASH). Bergamot is a plant whose fruit juice is enriched with flavonoids and…”
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13
The Potential for Natural Antioxidant Supplementation in the Early Stages of Neurodegenerative Disorders
Published in International journal of molecular sciences (09-04-2020)“…The neurodegenerative process is characterized by the progressive ultrastructural alterations of selected classes of neurons accompanied by imbalanced cellular…”
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14
Seizure susceptibility to various convulsant stimuli in the BTBR mouse model of autism spectrum disorders
Published in Frontiers in pharmacology (20-04-2023)“…Autism spectrum disorders (ASDs) are one of the most severe chronic childhood disorders in terms of prevalence, morbidity, and impact on society…”
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15
Therapeutic Use of Bee Venom and Potential Applications in Veterinary Medicine
Published in Veterinary sciences (01-02-2023)“…Apitherapy is a branch of alternative medicine that consists of the treatment of diseases through products collected, processed, and secreted by bees,…”
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The Role of Endothelial Dysfunction in Peripheral Blood Nerve Barrier: Molecular Mechanisms and Pathophysiological Implications
Published in International journal of molecular sciences (20-06-2019)“…The exchange of solutes between the blood and the nerve tissue is mediated by specific and high selective barriers in order to ensure the integrity of the…”
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Modulation of the nitric oxide/cGMP pathway in cardiac contraction and relaxation: Potential role in heart failure treatment
Published in Pharmacological research (01-10-2023)“…Evidence exists that heart failure (HF) has an overall impact of 1–2 % in the global population being often associated with comorbidities that contribute to…”
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The Bee Gut Microbiota: Bridging Infective Agents Potential in the One Health Context
Published in International journal of molecular sciences (01-04-2024)“…The bee gut microbiota plays an important role in the services the bees pay to the environment, humans and animals. Alongside, gut-associated microorganisms…”
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The Effect of Natural Antioxidants in the Development of Metabolic Syndrome: Focus on Bergamot Polyphenolic Fraction
Published in Nutrients (21-05-2020)“…Metabolic syndrome (MetS) represents a set of clinical findings that include visceral adiposity, insulin-resistance, high triglycerides (TG), low high-density…”
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Myelin Disturbances Produced by Sub-Toxic Concentration of Heavy Metals: The Role of Oligodendrocyte Dysfunction
Published in International journal of molecular sciences (14-09-2019)“…Evidence has been accumulated demonstrating that heavy metals may accumulate in various organs, leading to tissue damage and toxic effects in mammals. In…”
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