Search Results - "Palloni, Andrea"
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Predictive Biomarkers for Checkpoint Inhibitor-Based Immunotherapy in Hepatocellular Carcinoma: Where Do We Stand?
Published in Frontiers in oncology (17-12-2021)“…Hepatocellular carcinoma (HCC) remains the sixth most commonly diagnosed malignancy worldwide, still representing an important cause of cancer-related death…”
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Improvements in Systemic Therapies for Advanced Malignant Mesothelioma
Published in International journal of molecular sciences (21-06-2023)“…Malignant pleural mesothelioma (MPM) is a rare and aggressive malignancy associated with poor prognosis and a 5-year survival rate of 12%. Many drugs have been…”
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3
Metronomic capecitabine vs. best supportive care in Child-Pugh B hepatocellular carcinoma: a proof of concept
Published in Scientific reports (03-07-2018)“…There is a relative lack of evidence about systemic treatments in patients with hepatocellular carcinoma (HCC) and moderate liver dysfunction (Child-Pugh B)…”
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Percutaneous radiofrequency ablation in intrahepatic cholangiocarcinoma: a retrospective single-center experience
Published in International journal of hyperthermia (01-01-2020)“…Very few data are available in literature about the role of radiofrequency ablation (RFA) in intrahepatic cholangiocarcinoma (ICC) and previous studies are…”
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Immunotherapy in Pancreatic Cancer: Why Do We Keep Failing? A Focus on Tumor Immune Microenvironment, Predictive Biomarkers and Treatment Outcomes
Published in Cancers (14-05-2022)“…The advent of immunotherapy and targeted therapies has dramatically changed the outcomes of patients affected by many malignancies. Pancreatic cancer (PC)…”
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Activated FGFR2 signalling as a biomarker for selection of intrahepatic cholangiocarcinoma patients candidate to FGFR targeted therapies
Published in Scientific reports (07-02-2024)“…FGFR inhibitors have been developed to inhibit FGFR activation and signal transduction; notwithstanding, currently the selection of intrahepatic…”
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Asbestos exposure as an additional risk factor for small duct intrahepatic cholangiocarcinoma: a pilot study
Published in Scientific reports (13-02-2023)“…Intrahepatic cholangiocarcinoma (iCCA) is a rare malignancy, recently classified in small duct and large duct morphological subtypes. Growing evidence suggests…”
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Are FGFR and IDH1-2 alterations a positive prognostic factor in intrahepatic cholangiocarcinoma? An unresolved issue
Published in Frontiers in oncology (24-04-2023)“…Despite representing some of the most common and investigated molecular changes in intrahepatic cholangiocarcinoma (iCCA), the prognostic role of FGFR and…”
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Hacking Pancreatic Cancer: Present and Future of Personalized Medicine
Published in Pharmaceuticals (Basel, Switzerland) (15-07-2021)“…Pancreatic cancer (PC) is a recalcitrant disease characterized by high incidence and poor prognosis. The extremely complex genomic landscape of PC has a deep…”
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How to Choose Between Percutaneous Transhepatic and Endoscopic Biliary Drainage in Malignant Obstructive Jaundice: An Updated Systematic Review and Meta-analysis
Published in In vivo (Athens) (01-07-2020)“…BACKGROUND/AIMMalignant obstructive jaundice (MOJ) is a common condition caused by several primary and secondary cancers. We performed a systematic review and…”
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Non-Coding RNAs as Predictive Biomarkers to Current Treatment in Metastatic Colorectal Cancer
Published in International journal of molecular sciences (17-07-2017)“…The onset and selection of resistant clones during cancer treatment with chemotherapy or targeted therapy is a major issue in the clinical management of…”
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Is post‐transplant chemotherapy feasible in liver transplantation for colorectal cancer liver metastases?
Published in Cancer communications (London, England) (01-09-2020)“…A restaging computed tomography (CT) scan showed a liver-limited disease progression, so the patient received a second chemotherapeutic treatment with FOLFIRI…”
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Targeting BRAF-Mutant Biliary Tract Cancer: Recent Advances and Future Challenges
Published in Cancer Control (01-10-2020)“…Background: Biliary tract cancers (BTCs) represent a heterogeneous group of aggressive solid tumors with limited therapeutic options, and include gallbladder…”
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Intensive Follow-Up Program and Oncological Outcomes of Biliary Tract Cancer Patients after Curative-Intent Surgery: A Twenty-Year Experience in a Single Tertiary Medical Center
Published in Current oncology (Toronto) (19-07-2022)“…Aim. The aim of this research was to assess the impact of an intensive follow-up program on BTC patients who had received surgery with curative intent at a…”
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The Potential Role of Adjuvant Chemoradiotherapy in Patients with Microscopically Positive (R1) Surgical Margins after Resection of Cholangiocarcinoma
Published in Current oncology (Toronto) (04-05-2023)“…(1) Background: Biliary tract cancers (BTCs) are a heterogeneous group of neoplasms with dismal prognosis and the role of adjuvant chemoradiotherapy in…”
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Wilson disease, ABCC2 c.3972C > T polymorphism and primary liver cancers: suggestions from a familial cluster
Published in BMC medical genetics (18-11-2020)“…Polymorphisms in genes modulating xenobiotics metabolism, in particular the ABCC2 c.3972C > T single nucleotide polymorphism (SNP) at exon 28, have been…”
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Challenges in Repurposing Drugs in COVID-19 Pandemic. Debating on Potential New Refinements
Published in Frontiers in pharmacology (28-10-2020)Get full text
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Second-Line Chemotherapy in Elderly Patients with Advanced Biliary Tract Cancer: A Multicenter Real-World Study
Published in Medicina (Kaunas, Lithuania) (27-10-2022)“…Objectives: The ABC-06 and the NIFTY trials recently established the role of second-line chemotherapy (2L) in patients with advanced biliary tract cancer…”
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Membrane Localization of Human Equilibrative Nucleoside Transporter 1 in Tumor Cells May Predict Response to Adjuvant Gemcitabine in Resected Cholangiocarcinoma Patients
Published in The oncologist (Dayton, Ohio) (01-05-2016)“…Background. The use of gemcitabine as an adjuvant modality for cholangiocarcinoma (CC) is increasing, but limited data are available on predictive biomarkers…”
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Prognostic value of integrated morphofunctional imaging methods in inoperable intrahepatic cholangiocarcinoma
Published in Frontiers in medicine (06-07-2023)“…Intrahepatic cholangiocarcinoma (iCCA) is a disease characterized by rarity, heterogeneity, and high mortality, where surgical resection is often not possible…”
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