Search Results - "Palleroni, Alicia"

Rational Design of a Potent, Long-Lasting Form of Interferon:  A 40 kDa Branched Polyethylene Glycol-Conjugated Interferon α-2a for the Treatment of Hepatitis C by Bailon, Pascal, Palleroni, Alicia, Schaffer, Carol A, Spence, Cheryl L, Fung, Wen-Jian, Porter, Jill E, Ehrlich, George K, Pan, Wen, Xu, Zhi-Xin, Modi, Marlene W, Farid, Adrienne, Berthold, Wolfgang, Graves, Mary

“…A potent, long-lasting form of interferon α-2a mono-pegylated with a 40 kilodalton branched poly(ethylene glycol) was designed, synthesized, and characterized…”
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Antitumor activity of interleukin 12 in preclinical models by BRUNDA, M. J, LUISTRO, L, RUMENNIK, L, WRIGHT, R. B, DVOROZNIAK, M, AGLIONE, A, WIGGINTON, J. M, WILTROUT, R. H, HENDRZAK, J. A, PALLERONI, A. V

“…Interleukin 12 (IL-12) is a heterodimeric cytokine with a number of biological effects that are consistent with its potential role as an antitumor agent. The…”
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In vivo immortalization of murine peritoneal macrophages: a new rapid and efficient method for obtaining macrophage cell lines by Adami, C, Brunda, M J, Palleroni, A V

“…Although several murine macrophage (m phi) cell lines from different sites have previously been obtained by in vitro infection with the J2 murine retrovirus,…”
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Tumoricidal alveolar macrophage and tumor infiltrating macrophage cell lines by Palleroni, A V, Varesio, L, Wright, R B, Brunda, M J

“…Continuous alveolar macrophage (AM) and tumor-infiltrated (TIM) cell lines have been generated from C57B16J mice by in vitro infection with the J2 retrovirus…”
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Tumoricidal activity and cytokine secretion by tumor-infiltrating macrophages by Brunda, M J, Sulich, V, Wright, R B, Palleroni, A V

“…Murine macrophages from different anatomical sites were compared for their ability to become tumoricidal and to secrete interleukin-1 (IL-1) and tumor necrosis…”
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Positional Isomers of Monopegylated Interferon α-2a: Isolation, Characterization, and Biological Activity by Monkarsh, Seth P., Ma, Yuemei, Aglione, Anthony, Bailon, Pascal, Ciolek, Doreen, Debarbieri, Barabara, Graves, Mary C., Hollfelder, Kurt, Michel, Hanspeter, Palleroni, Alicia, Porter, Jill E., Russoman, Emil, Roy, Swapan, Pan, Yu-Ching E.

“…The success of recombinant interferon α in the clinic in part is limited by two properties of the protein: short serum half-life and immunogenicity. To improve…”
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Relationship between binding affinities to cellular retinoic acid-binding protein and in vivo and in vitro properties for 18 retinoids by Trown, P W, Palleroni, A V, Bohoslawec, O, Richelo, B N, Halpern, J M, Gizzi, N, Geiger, R, Lewinski, C, Machlin, L J, Jetten, A, Jetten, M E

“…A new rapid assay has been developed for measurement of the binding of [3H]retinoic acid to cellular retinoic acid-binding protein. The assay, which uses…”
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Rational Design of a Potent, Long-Lasting Form of Interferon: A 40 kDa Branched Polyethylene Glycol-Conjugated Interferon a-2a for the Treatment of Hepatitis C by Pascal Bailon, Pascal Bailon Alicia Palleroni, Schaffer, Carol A, Spence, Cheryl L, Fung, Wen-Jian, Porter, Jill E, Ehrlich, George K, Pan, Wen, Xu, Zhi-Xin, Modi, Marlene W, Farid, Adrienne, Berthold, Wolfgang

“…A potent, long-lasting form of interferon *a-2a mono-pegylated with a 40 kilodalton branched poly(ethylene glycol) was designed, synthesized, and…”
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Choroidal concentration of interferon after retrobulbar injection by Lincoff, H, Stanga, P, Movshovich, A, Palleroni, A, Madjarov, B, Rivera, R, Silverman, R

“…To determine whether recombinant human interferon alpha-2a (IFN alpha-2a) would diffuse into the choroid in significant amounts from a retrobulbar depot. One…”
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Interleukin-12: murine models of a potent antitumor agent by Brunda, M J, Luistro, L, Rumennik, L, Wright, R B, Wigginton, J M, Wiltrout, R H, Hendrzak, J A, Palleroni, A V

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Incidence and clinical significance of neutralizing antibodies in patients receiving recombinant interferon alfa-2a by intramuscular injection by Itri, L M, Campion, M, Dennin, R A, Palleroni, A V, Gutterman, J U, Groopman, J E, Trown, P W

“…More than 1600 patients with neoplastic disorders have received recombinant human interferon alfa-2a (Roferon-A, Hoffmann-La Roche, Nutley, NJ) as part of…”
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A rapid and efficient method for establishing peritoneal macrophage cell lines by Palleroni, Alicia Vallejo

“…Inoculation of the murine J2 retrovirus into the peritoneal cavity of mice which have been previously injected with Brewer's thioglycolate medium, results in…”
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A second-generation enzyme immunoassay for detection of antibodies to IFN-alpha by Palleroni, A V, Specian, A, Aglione, A, Dvorozniak, M T, Raman, J

“…We have developed a solid-phase enzyme-linked immunoassay (EIA) for detecting antibodies to interferon-alpha2 (IFN-alpha2) in serum or plasma. In this assay,…”
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Normal Human Epidermis Contains an Interferon-Like Protein by Yaar, Mina, Palleroni, Alicia V., Gilchrest, Barbara A.

“…Interferons have been postulated to participate in growth regulation of normal body tissues and are known to inhibit growth of human epidermal keratinocytes in…”
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A sensitive radioimmunoassay for detection of antibodies to recombinant human interferon-alpha A by Palleroni, A V, Trown, P W

“…A radioimmunoassay (RIA) for the detection of antibodies to recombinant human leukocyte interferon A (rHuIFN-alpha A) in human serum has been developed and…”
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