Search Results - "Pallardó, F V"

Aging of the liver: Age‐associated mitochondrial damage in intact hepatocytes by Sastre, J, Pallardó, F V, Plá, R, Pellín, A, Juan, G, O'Connor, J E, Estrela, J M, Miquel, J, Viña, J

“…Mitochondrial damage may be a major cause of cellular aging. So far, this hypothesis had only been tested using isolated mitochondria. The aim of this study…”
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L-cysteine and glutathione metabolism are impaired in premature infants due to cystathionase deficiency by Viña, J, Vento, M, García-Sala, F, Puertes, IR, Gascó, E, Sastre, J, Asensi, M, Pallardó, FV

“…There are conflicting reports in the literature as to whether L-cysteine is an essential amino acid in premature infants as the result of the absence of…”
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Free radicals in exhaustive physical exercise: mechanism of production, and protection by antioxidants by Viña, J, Gomez-Cabrera, M C, Lloret, A, Marquez, R, Miñana, J B, Pallardó, F V, Sastre, J

“…Moderate exercise is a healthy practice. However, exhaustive exercise generates free radicals. This can be evidenced by increases in lipid peroxidation,…”
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A new mass spectrometry-based method for the quantification of histones in plasma from septic shock patients by García-Giménez, J. L., Romá-Mateo, C., Carbonell, N., Palacios, L., Peiró-Chova, L., García-López, E., García-Simón, M., Lahuerta, R., Gimenez-Garzó, C., Berenguer-Pascual, E., Mora, M. I., Valero, M. L., Alpízar, A., Corrales, F. J., Blanquer, J., Pallardó, F. V.

“…The aim of this study was to develop a novel method to detect circulating histones H3 and H2B in plasma based on multiple reaction monitoring targeted mass…”
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Circulating miR-323-3p is a biomarker for cardiomyopathy and an indicator of phenotypic variability in Friedreich’s ataxia patients by Seco-Cervera, M., González-Rodríguez, D., Ibáñez-Cabellos, J. S., Peiró-Chova, L., González-Cabo, P., García-López, E., Vílchez, J. J., Sanz-Gallego, I., Pallardó, F. V., García-Giménez, J. L.

“…MicroRNAs (miRNAs) are noncoding RNAs that contribute to gene expression modulation by regulating important cellular pathways. In this study, we used small RNA…”
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Role of mitochondrial oxidative stress to explain the different longevity between genders: protective effect of estrogens by Viña, J, Sastre, J, Pallardó, F V, Gambini, J, Borrás, C

“…Females live longer than males. Work from our laboratory has shown that this may be due to the up-regulation of longevity-associated genes by estrogens…”
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Epigenetic biomarkers: A new perspective in laboratory diagnostics by García-Giménez, J.L., Sanchis-Gomar, F., Lippi, G., Mena, S., Ivars, D., Gomez-Cabrera, M.C., Viña, J., Pallardó, F.V.

“…Epigenetics comprises the study of chemical modifications in the DNA and histones that regulates the gene expression or cellular phenotype. However, during the…”
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Circulating mononuclear cells nuclear factor-kappa B activity, plasma xanthine oxidase, and low grade inflammatory markers in adult patients with familial hypercholesterolaemia by Real, J. T., Martínez-Hervás, S., García-García, A. B., Civera, M., Pallardó, F. V., Ascaso, J. F., Viña, J. R., Chaves, F. J., Carmena, R.

“…Eur J Clin Invest 2010; 40 (2): 89–94 Background  Few data are available on circulating mononuclear cells nuclear factor‐kappa B (NF‐kB) activity and plasma…”
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Extracellular Histones Activate Endothelial NLRP3 Inflammasome and are Associated with a Severe Sepsis Phenotype by Garcia, Jesus Beltran, Verdegal, Rebeca Osca, Cremades, Daniel Perez, Novella, Susana, Hermenegildo, Carlos, Pallardo, Federico V, Gimenez, Jose Luis Garcia

“…Introduction: Circulating extracellular histones acquire relevance as cytotoxic mediators in sepsis. Extracellular histones act as damage-associated molecular…”
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A high-performance liquid chromatography method for measurement of oxidized glutathione in biological samples by Asensi, M, Sastre, J, Pallardó, F V, García de la Asunción, J, Estrela, J M, Viña, J

“…A high-performance liquid chromatography method to determine oxidized glutathione (GSSG) in biological samples with ultraviolet-visible detection using…”
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Oxidative damage to mitochondrial DNA and glutathione oxidation in apoptosis: studies in vivo and in vitro by Esteve, J. M., Mompo, J., Asuncion, J. Garcia, Sastre, J., Asensi, M., Bolx, J., Viña, J. R., Viña, J., Pallardó, F. V.

“…ABSTRACT Free radicals may be involved in apoptosis although this is the subject of some controversy. Furthermore, the source of free radicals in apoptotic…”
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Effect of intermittent hypoxia on hematological parameters after recombinant human erythropoietin administration by Sanchis-Gomar, F., Martinez-Bello, V. E., Domenech, E., Nascimento, A. L., Pallardo, F. V., Gomez-Cabrera, Mari Carmen, Vina, J.

“…Recent publications reflect the anti-doping authorities’ concern about the use of altitude simulator systems as violating the spirit of sport criterion (Levine…”
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Oxidative stress as a signal to up-regulate gamma-cystathionase in the fetal-to-neonatal transition in rats by Martín, J A, Pereda, J, Martínez-López, I, Escrig, R, Miralles, V, Pallardó, F V, Viña, J R, Vento, M, Viña, J, Sastre, J

“…Hepatic gamma-cystathionase, a rate-limiting enzyme for the synthesis of L-cysteine from L-methionine in the trans-sulphuration pathway, exhibits significantly…”
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Late onset administration of oral antioxidants prevents age-related loss of motor co-ordination and brain mitochondrial DNA damage by Pallardó, F V, Asensi, M, García de la Asunción, J, Antón, V, Lloret, A, Sastre, J, Viña, J

“…We have studied the effect of aging on brain glutathione redox ratio, on brain mitochondrial DNA damage and on motor co-ordination in mice and the possible…”
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Exhaustive physical exercise causes oxidation of glutathione status in blood: prevention by antioxidant administration by Sastre, J, Asensi, M, Gascó, E, Pallardó, F V, Ferrero, J A, Furukawa, T, Viña, J

“…We have studied the effect of exhaustive concentric physical exercise on glutathione redox status and the possible relationship between blood glutathione…”
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Mechanism of Free Radical Production in Exhaustive Exercise in Humans and Rats; Role of Xanthine Oxidase and Protection by Allopurinol by Viña, José, Gimeno, Amparo, Sastre, Juan, Desco, Carmen, Asensi, Miguel, Pallardó, Federico V., Cuesta, Andrés, Ferrero, José Antonio, Terada, Lance S., Repine, John E.

“…Exhaustive exercise generates free radicals. However, the source of this oxidative damage remains controversial. The aim of this paper was to study further the…”
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Na + dependent glutamate transporters (EAAT1, EAAT2, and EAAT3) in primary astrocyte cultures: effect of oxidative stress by Miralles, Vicente J, Martı́nez-López, Itziar, Zaragozá, Rosa, Borrás, Elisa, Garcı́a, Concha, Pallardó, Federico V, Viña, Juan R

“…The Na +-dependent l-glutamate transporters EAAT1(GLAST), EAAT2 (GLT-1) and EAAT3 (EAAC1) are expressed in primary astrocyte cultures, showing that the EAAT3…”
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Vitamins C and E prevent AZT-induced leukopenia and loss of cellularity in bone marrow. Studies in mice by García-de-la-Asunción, J, Gómez-Cambronero, L G, Del Olmo, M L, Pallardó, F V, Sastre, J, Viña, J

“…A major limitation in the use of AZT for AIDS treatment is the occurrence of side effects, such as leukopenia. The effects of antioxidant vitamins C and E on…”
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Pentoxifylline ameliorates cerulein-induced pancreatitis in rats: role of glutathione and nitric oxide by Gómez-Cambronero, L, Camps, B, de La Asunción, J G, Cerdá, M, Pellín, A, Pallardó, F V, Calvete, J, Sweiry, J H, Mann, G E, Viña, J, Sastre, J

“…Reactive oxygen radicals, nitric oxide, and cytokines have been implicated in the initiation of pancreatic tissue damage and impairment of the pancreatic…”
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Kinetics of GLUT1 and GLUT4 glucose transporters expressed in Xenopus oocytes by NISHIMURA, H, PALLARDO, F. V, SEIDNER, G. A, VANNUCCI, S, SIMPSON, I. A, BIRNBAUM, M. J

“…The predominant mechanism by which insulin activates glucose transport in muscle and adipose tissue is by affecting the redistribution of the facilitated…”
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