Search Results - "Paljug, William R."

Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease by Ikonomovic, Milos D., Klunk, William E., Abrahamson, Eric E., Mathis, Chester A., Price, Julie C., Tsopelas, Nicholas D., Lopresti, Brian J., Ziolko, Scott, Bi, Wenzhu, Paljug, William R., Debnath, Manik L., Hope, Caroline E., Isanski, Barbara A., Hamilton, Ronald L., DeKosky, Steven T.

“…The positron emission tomography (PET) radiotracer Pittsburgh Compound-B (PiB) binds with high affinity to β-pleated sheet aggregates of the amyloid-β (Aβ)…”
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Early AD pathology in a [C-11]PiB-negative case: a PiB-amyloid imaging, biochemical, and immunohistochemical study by Ikonomovic, Milos D., Abrahamson, Eric E., Price, Julie C., Hamilton, Ronald L., Mathis, Chester A., Paljug, William R., Debnath, Manik L., Cohen, Anne D., Mizukami, Katsuyoshi, DeKosky, Steven T., Lopez, Oscar L., Klunk, William E.

“…Amyloid-β (Aβ) deposits are detectable in the brain in vivo using positron emission tomography (PET) and [C-11]-labeled Pittsburgh Compound B ([C-11]PiB);…”
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β-Amyloid 42/40 ratio and kalirin expression in Alzheimer disease with psychosis by Murray, Patrick S, Kirkwood, Caitlin M, Gray, Megan C, Ikonomovic, Milos D, Paljug, William R, Abrahamson, Eric E, Henteleff, Ruth A, Hamilton, Ronald L, Kofler, Julia K, Klunk, William E, Lopez, Oscar L, Penzes, Peter, Sweet, Robert A

“…Abstract Psychosis in Alzheimer disease differentiates a subgroup with more rapid decline, is heritable, and aggregates within families, suggesting a distinct…”
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PYROGLUTAMATE AND FULL-LENGTH AMYLOID-B CONCENTRATIONS IN THE SUPERIOR FRONTAL CORTEX ACROSS CLINICAL STAGES OF ALZHEIMER’S DISEASE by Abrahamson, Eric E, Kruszka, Gillian I, Mi, Zhiping, Paljug, William R, Debnath, Manik L, Klunk, William E, Mufson, Elliott J, Ikonomovic, Milos D

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Caspase inhibition therapy abolishes brain trauma-induced increases in Aβ peptide: Implications for clinical outcome by Abrahamson, Eric E., Ikonomovic, Milos D., Ciallella, John R., Hope, Caroline E., Paljug, William R., Isanski, Barbara A., Flood, Dorothy G., Clark, Robert S.B., DeKosky, Steven T.

“…The detrimental effects of traumatic brain injury (TBI) on brain tissue integrity involve progressive axonal damage, necrotic cell loss, and both acute and…”
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BOTH FULL-LENGTH AND PYROGLUTAMATE AMYLOID-BETA ARE ASSOCIATED WITH PITTSBURGH COMPOUND-B BINDING IN THE PRECUNEUS ACROSS CLINICAL STAGES OF ALZHEIMER’S DISEASE by Pivtoraiko, Violetta, Abrahamson, Eric E., Paljug, William R., Debnath, Manik L., Mathis, Chester, Klunk, William E., Mufson, Elliott J., Ikonomovic, Milos D.

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P1‐171: BOTH FULL‐LENGTH AND PYROGLUTAMATE AMYLOID‐BETA ARE ASSOCIATED WITH PITTSBURGH COMPOUND‐B BINDING IN THE PRECUNEUS ACROSS CLINICAL STAGES OF ALZHEIMER'S DISEASE by Pivtoraiko, Violetta, Abrahamson, Eric E., Paljug, William R., Debnath, Manik L., Mathis, Chester, Klunk, William E., Mufson, Elliott J., Ikonomovic, Milos D.

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P2‐288: Pyroglutamate and Full‐Length Amyloid‐B Concentrations in the Superior Frontal Cortex Across Clinical Stages of Alzheimer's Disease by Abrahamson, Eric E., Kruszka, Gillian I., Mi, Zhiping, Paljug, William R., Debnath, Manik L., Klunk, William E., Mufson, Elliott J., Ikonomovic, Milos D.

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Caspase inhibition therapy abolishes brain trauma-induced increases in Abeta peptide: implications for clinical outcome by Abrahamson, Eric E, Ikonomovic, Milos D, Ciallella, John R, Hope, Caroline E, Paljug, William R, Isanski, Barbara A, Flood, Dorothy G, Clark, Robert S B, DeKosky, Steven T

“…The detrimental effects of traumatic brain injury (TBI) on brain tissue integrity involve progressive axonal damage, necrotic cell loss, and both acute and…”
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P2-369: Correlation analysis of the histofluorescence of an analogue of Pittsburgh Compound-B and Aβ peptide levels in Alzheimer’s disease by Ikonomovic, Milos D., Abrahamson, Eric E., Hope, Caroline E., Paljug, William R., Isanski, Barbara A., Debnath, Manik L., Mathis, Chester A., DeKosky, Steven T., Klunk, William E.

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Binding of the amyloid-imaging PET tracer, Pittsburgh Compound-B, to post-mortem human brain tissue from the AN-1792 immunotherapy trial by Klunk, William E., Ikonomovic, Milos D., Masliah, Eliezer, Ferrer, Isidro, Kirby, Louis C., Price, Julie C., Abrahamson, Eric E., Paljug, William R., Mathis, Chester A., DeKosky, Steven T.

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Changes in expression of amyloid precursor protein and interleukin-1beta after experimental traumatic brain injury in rats by Ciallella, John R, Ikonomovic, Milos D, Paljug, William R, Wilbur, Yetta I, Dixon, C Edward, Kochanek, Patrick M, Marion, Donald W, DeKosky, Steven T

“…There is increasing evidence linking neurodegenerative mechanisms in Alzheimer's disease (AD) and traumatic brain injury (TBI), including increased production…”
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Chronic dizocilpine (MK-801) reversibly delays GABA(A) receptor maturation in cerebellar granule neurons in vitro by Wang, X H, Zhu, W J, Corsi, L, Ikonomovic, S, Paljug, W R, Vicini, S, Grayson, D R

“…We investigated the effect of chronically blocking NMDA receptor stimulation to examine changes in GABA(A) receptor expression and pharmacology in cerebellar…”
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Thyroid hormone receptor messenger ribonucleic acid in human granulosa and ovarian stromal cells by Wakim, A N, Paljug, W R, Jasnosz, K M, Alhakim, N, Brown, A B, Burholt, D R

“…To examine whether mRNA for thyroid hormone receptors alpha and beta is present in human granulosa cells in nonstimulated ovaries. Paraffin-embedded sections…”
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Chronic Dizocilpine (MK‐801) Reversibly Delays GABAA Receptor Maturation in Cerebellar Granule Neurons In Vitro by Wang, Xiao‐Hui, Zhu, Wei Jian, Corsi, Lorenzo, Ikonomovic, Snezana, Paljug, William R., Vicini, Stefano, Grayson, Dennis R.

“…: We investigated the effect of chronically blocking NMDA receptor stimulation to examine changes in GABAA receptor expression and pharmacology in cerebellar…”
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Hypothermia-Enhanced Human Tumor Cell Radiosensitivity by Burton, Steven A., Paljug, William R., Kalnicki, Shalom, Werts, E.Day

“…Ablation of neoplastic disease by freezing has found increasing utility as a potential therapeutic modality. To assess the effect of cooling temperatures on…”
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Radiation survival of two human cervical carcinoma cell lines after multifraction irradiation by Werts, E D, Burholt, D R, Paljug, W R, Polizotto, S L, Yann, V M

“…Multifraction irradiation may contribute to radiation therapy treatment failure if selection of radiation resistant subpopulations occurs. We sought to…”
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Association of increased cortical soluble abeta42 levels with diffuse plaques after severe brain injury in humans by DeKosky, Steven T, Abrahamson, Eric E, Ciallella, John R, Paljug, William R, Wisniewski, Stephen R, Clark, Robert S B, Ikonomovic, Milos D

“…Traumatic brain injury (TBI) is an environmental risk factor for developing Alzheimer disease. This may be due, in part, to changes associated with…”
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