Search Results - "Palin, Anais"
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1
LJ000328, a novel ALK2/3 kinase inhibitor, represses hepcidin and significantly improves the phenotype of IRIDA
Published in Haematologica (Roma) (01-08-2020)Get full text
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2
Endoplasmic reticulum stress controls iron metabolism through TMPRSS6 repression and hepcidin mRNA stabilization by RNA-binding protein HuR
Published in Haematologica (Roma) (01-04-2021)“…The liver hormone hepcidin controls the main inflows of iron into plasma by binding to and inducing the degradation or the occlusion of the iron export…”
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3
A human anti-matriptase-2 antibody limits iron overload, α-globin aggregates, and splenomegaly in β-thalassemic mice
Published in Blood advances (23-04-2024)“…•RLYB331 is a human antibody that increases hepcidin, reduces iron overload, and ameliorates ineffective erythropoiesis in β-thalassemia•Combination with…”
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4
Generation and Characterisation of KY1066, a Fully Human Antibody Targeting the Enzymatic Activity of Matriptase-2 for the Treatment of Iron Overload in Beta Thalassemia
Published in Blood (13-11-2019)“…Beta thalassemia is an inherited hemoglobinopathy caused by a genetic defect in beta-globin gene and characterised by ineffective erythropoiesis, iron…”
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Journal Article