Search Results - "Palidwor, Gareth A"
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1
A general model of codon bias due to GC mutational bias
Published in PloS one (27-10-2010)“…In spite of extensive research on the effect of mutation and selection on codon usage, a general model of codon usage bias due to mutational bias has been…”
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2
Transcriptional Dominance of Pax7 in Adult Myogenesis Is Due to High-Affinity Recognition of Homeodomain Motifs
Published in Developmental cell (12-06-2012)“…Pax3 and Pax7 regulate stem cell function in skeletal myogenesis. However, molecular insight into their distinct roles has remained elusive. Using gene…”
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3
Accuracy and reproducibility of somatic point mutation calling in clinical-type targeted sequencing data
Published in BMC medical genomics (15-10-2020)“…Treating cancer depends in part on identifying the mutations driving each patient's disease. Many clinical laboratories are adopting high-throughput sequencing…”
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MaSC: mappability-sensitive cross-correlation for estimating mean fragment length of single-end short-read sequencing data
Published in Bioinformatics (15-02-2013)“…Reliable estimation of the mean fragment length for next-generation short-read sequencing data is an important step in next-generation sequencing analysis…”
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5
Functional and genomic analyses of alpha-solenoid proteins
Published in PloS one (21-11-2013)“…Alpha-solenoids are flexible protein structural domains formed by ensembles of alpha-helical repeats (Armadillo and HEAT repeats among others). While homology…”
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6
Mtf2-PRC2 control of canonical Wnt signaling is required for definitive erythropoiesis
Published in Cell discovery (01-05-2018)“…Polycomb repressive complex 2 (PRC2) accessory proteins play substoichiometric, tissue-specific roles to recruit PRC2 to specific genomic loci or increase…”
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7
Detection of alpha-rod protein repeats using a neural network and application to huntingtin
Published in PLoS computational biology (01-03-2009)“…A growing number of solved protein structures display an elongated structural domain, denoted here as alpha-rod, composed of stacked pairs of anti-parallel…”
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8
Cis-regulatory determinants of MyoD function
Published in Nucleic acids research (21-08-2018)“…Abstract Muscle-specific transcription factor MyoD orchestrates the myogenic gene expression program by binding to short DNA motifs called E-boxes within…”
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9
Peer2ref: a peer-reviewer finding web tool that uses author disambiguation
Published in BioData mining (07-09-2012)“…Reviewer and editor selection for peer review is getting harder for authors and publishers due to the specialization onto narrower areas of research carried by…”
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10
Recent developments in StemBase: a tool to study gene expression in human and murine stem cells
Published in BMC research notes (10-03-2009)“…Currently one of the largest online repositories for human and mouse stem cell gene expression data, StemBase was first designed as a simple web-interface to…”
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11
BIDCHIPS: bias decomposition and removal from ChIP-seq data clarifies true binding signal and its functional correlates
Published in Epigenetics & chromatin (17-09-2015)“…Unraveling transcriptional regulatory networks is a central problem in molecular biology and, in this quest, chromatin immunoprecipitation and sequencing…”
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12
Chromatin tandem affinity purification sequencing
Published in Nature protocols (01-08-2013)“…Chromatin immunoprecipitation coupled with ultra-high-throughput sequencing (ChIP-seq) is a widely used method for mapping the interactions of proteins with…”
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13
Transcriptional profiling of skeletal muscle reveals factors that are necessary to maintain satellite cell integrity during ageing
Published in Mechanisms of ageing and development (2010)“…Skeletal muscle ageing is characterized by faulty degenerative/regenerative processes that promote the decline of its mass, strength, and endurance. In this…”
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14
StemBase: a resource for the analysis of stem cell gene expression data
Published in Methods in molecular biology (Clifton, N.J.) (2007)“…StemBase is a database of gene expression data obtained from stem cells and derivatives mainly from mouse and human using DNA microarrays and Serial Analysis…”
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15
MLTrends: Graphing MEDLINE term usage over time
Published in Journal of biomedical discovery and collaboration (25-01-2010)“…The MEDLINE database of medical literature is routinely used by researchers and doctors to find articles pertaining to their area of interest. Insight into…”
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16
Detection of Alpha-Rod Protein Repeats Using a Neural Network and Application to Huntingtin: e1000304
Published in PLoS computational biology (01-03-2009)“…A growing number of solved protein structures display an elongated structural domain, denoted here as alpha-rod, composed of stacked pairs of anti-parallel…”
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Tissue-specific codon usage in mouse
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Dissertation