Search Results - "Palesch, Y Y"

Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA by Johnston, S. Claiborne, Easton, J. Donald, Farrant, Mary, Barsan, William, Conwit, Robin A, Elm, Jordan J, Kim, Anthony S, Lindblad, Anne S, Palesch, Yuko Y

“…In this international, randomized trial, patients with minor stroke or TIA who received clopidogrel plus aspirin had a lower risk of major ischemic events but…”
Get full text

Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH) II: Design, Methods, and Rationale by Qureshi, A. I., Palesch, Y. Y.

“…The December 2003 report from the National Institute of Neurological Disorders and Stroke (NINDS) Workshop on priorities for clinical research in intracerebral…”
Get full text

Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging by Albers, Gregory W, Marks, Michael P, Kemp, Stephanie, Christensen, Soren, Tsai, Jenny P, Ortega-Gutierrez, Santiago, McTaggart, Ryan A, Torbey, Michel T, Kim-Tenser, May, Leslie-Mazwi, Thabele, Sarraj, Amrou, Kasner, Scott E, Ansari, Sameer A, Yeatts, Sharon D, Hamilton, Scott, Mlynash, Michael, Heit, Jeremy J, Zaharchuk, Greg, Kim, Sun, Carrozzella, Janice, Palesch, Yuko Y, Demchuk, Andrew M, Bammer, Roland, Lavori, Philip W, Broderick, Joseph P, Lansberg, Maarten G

“…In this trial in patients with stroke who had a mismatch between sizes of early infarction and a hypoperfused brain region, endovascular thrombectomy at 6 to…”
Get full text

Time to angiographic reperfusion and clinical outcome after acute ischaemic stroke: an analysis of data from the Interventional Management of Stroke (IMS III) phase 3 trial by Khatri, Pooja, Prof, Yeatts, Sharon D, PhD, Mazighi, Mikael, MD, Broderick, Joseph P, Prof, Liebeskind, David S, Prof, Demchuk, Andrew M, Prof, Amarenco, Pierre, Prof, Carrozzella, Janice, MSN, Spilker, Judith, BSN, Foster, Lydia D, PhD, Goyal, Mayank, Prof, Hill, Michael D, Prof, Palesch, Yuko Y, Prof, Jauch, Edward C, Prof, Haley, E Clarke, Prof, Vagal, Achala, MD, Tomsick, Thomas A, Prof

“…Summary Background The IMS III trial did not show a clinical benefit of endovascular treatment compared with intravenous alteplase (recombinant tissue…”
Get full text

The AtRial Cardiopathy and Antithrombotic Drugs In prevention After cryptogenic stroke randomized trial: Rationale and methods by Kamel, Hooman, Longstreth, WT, Tirschwell, David L, Kronmal, Richard A, Broderick, Joseph P, Palesch, Yuko Y, Meinzer, Caitlyn, Dillon, Catherine, Ewing, Irene, Spilker, Judith A, Di Tullio, Marco R, Hod, Eldad A, Soliman, Elsayed Z, Chaturvedi, Seemant, Moy, Claudia S, Janis, Scott, Elkind, Mitchell SV

“…Rationale Recent data suggest that a thrombogenic atrial substrate can cause stroke in the absence of atrial fibrillation. Such an atrial cardiopathy may…”
Get full text

Collaterals at Angiography and Outcomes in the Interventional Management of Stroke (IMS) III Trial by LIEBESKIND, David S, TOMSICK, Thomas A, ZAIDAT, Osama O, HUSSAIN, Syed I, GOYAL, Mayank, MENON, Bijoy K, FIRAS AL ALI, YAN, Bernard, PALESCH, Yuko Y, BRODERICK, Joseph P, FOSTER, Lydia D, YEATTS, Sharon D, CARROZZELLA, Janice, DEMCHUK, Andrew M, JOVIN, Tudor G, KHATRI, Pooja, VON KUMMER, Ruediger, SUGG, Rebecca M

“…Endovascular strategies provide unique opportunity to correlate angiographic measures of collateral circulation at the time of endovascular therapy. We…”
Get full text

Revascularization Results in the Interventional Management of Stroke II Trial by Tomsick, T, Broderick, J, Carrozella, J, Khatri, P, Hill, M, Palesch, Y, Khoury, J, Interventional Management of Stroke II Investigators

“…Our aim was to detail revascularization results, including impact on outcome and mortality, in the Interventional Management of Stroke (IMS) II trial. IMS II…”
Get full text

Recanalization and clinical outcome of occlusion sites at baseline CT angiography in the Interventional Management of Stroke III trial by Demchuk, Andrew M, Goyal, Mayank, Yeatts, Sharon D, Carrozzella, Janice, Foster, Lydia D, Qazi, Emmad, Hill, Michael D, Jovin, Tudor G, Ribo, Marc, Yan, Bernard, Zaidat, Osama O, Frei, Donald, von Kummer, Rüdiger, Cockroft, Kevin M, Khatri, Pooja, Liebeskind, David S, Tomsick, Thomas A, Palesch, Yuko Y, Broderick, Joseph P

“…To use baseline computed tomographic (CT) angiography to analyze imaging and clinical end points in an Interventional Management of Stroke III cohort to…”
Get full text

High Dose Deferoxamine in Intracerebral Hemorrhage (Hi-Def) Trial: Rationale, Design, and Methods by Yeatts, Sharon D., Palesch, Yuko Y., Moy, Claudia S., Selim, Magdy

“…Background Hemoglobin degradation products, in particular iron, have been implicated in secondary neuronal injury following intracerebral hemorrhage (ICH). The…”
Get full text

High-dose albumin treatment for acute ischaemic stroke (ALIAS) part 2: a randomised, double-blind, phase 3, placebo-controlled trial by Ginsberg, Myron D, Dr Prof, Palesch, Yuko Y, Prof, Hill, Michael D, Prof, Martin, Renee H, PhD, Moy, Claudia S, PhD, Barsan, William G, Prof, Waldman, Bonnie D, JD, Tamariz, Diego, MD, Ryckborst, Karla J, RN

“…Summary Background In animal models of ischaemic stroke, 25% albumin reduced brain infarction and improved neurobehavioural outcome. In a pilot clinical trial,…”
Get full text

Clinical Outcomes Depending on Acute Blood Pressure After Cerebral Hemorrhage by Toyoda, Kazunori, Koga, Masatoshi, Yamamoto, Haruko, Foster, Lydia, Palesch, Yuko Y., Wang, Yongjun, Sakai, Nobuyuki, Hara, Takayuki, Hsu, Chung Y., Itabashi, Ryo, Sato, Shoichiro, Fukuda‐Doi, Mayumi, Steiner, Thorsten, Yoon, Byung‐Woo, Hanley, Daniel F., Qureshi, Adnan I.

“…Objective To determine the association between clinical outcomes and acute systolic blood pressure (SBP) levels achieved after intracerebral hemorrhage (ICH)…”
Get full text

Computed Tomographic Colonography (Virtual Colonoscopy): A Multicenter Comparison With Standard Colonoscopy for Detection of Colorectal Neoplasia by Cotton, Peter B, Durkalski, Valerie L, Pineau, Benoit C, Palesch, Yuko Y, Mauldin, Patrick D, Hoffman, Brenda, Vining, David J, Small, William C, Affronti, John, Rex, Douglas, Kopecky, Kenyon K, Ackerman, Susan, Burdick, J. Steven, Brewington, Cecelia, Turner, Mary A, Zfass, Alvin, Wright, Andrew R, Iyer, Revathy B, Lynch, Patrick, Sivak, Michael V, Butler, Harold

“…CONTEXT Conventional colonoscopy is the best available method for detection of colorectal cancer; however, it is invasive and not without risk. Computed…”
Get full text

Blood Pressure-Attained Analysis of ATACH 2 Trial by Qureshi, Adnan I, Palesch, Yuko Y, Foster, Lydia D, Barsan, William G, Goldstein, Joshua N, Hanley, Daniel F, Hsu, Chung Y, Moy, Claudia S, Qureshi, Mushtaq H, Silbergleit, Robert, Suarez, Jose I, Toyoda, Kazunori, Yamamoto, Haruko

“…BACKGROUND AND PURPOSE—We compared the rates of death or disability, defined by modified Rankin Scale score of 4 to 6, at 3 months in patients with…”
Get full text

Endovascular Therapy of M2 Occlusion in IMS III: Role of M2 Segment Definition and Location on Clinical and Revascularization Outcomes by Tomsick, T A, Carrozzella, J, Foster, L, Hill, M D, von Kummer, R, Goyal, M, Demchuk, A M, Khatri, P, Palesch, Y, Broderick, J P, Yeatts, S D, Liebeskind, D S

“…Uncertainty persists regarding the safety and efficacy of endovascular therapy of M2 occlusions following IV tPA. We reviewed the impact of revascularization…”
Get full text

Comparison of multistate Markov modeling with contemporary outcomes in a reanalysis of the NINDS tissue plasminogen activator for acute ischemic stroke treatment trial by Cassarly, Christy, Martin, Renee' H, Chimowitz, Marc, Peña, Edsel A, Ramakrishnan, Viswanathan, Palesch, Yuko Y

“…Historically, ordinal measures of functional outcome have been dichotomized for the primary analysis in acute stroke therapy trials. A number of alternative…”
Get full text

Pancreatic stenting prevents pancreatitis after biliary sphincterotomy in patients with sphincter of Oddi dysfunction by Tarnasky, Paul R., Palesch, Yuko Y., Cunningham, John T., Mauldin, Patrick D., Cotton, Peter B., Hawes, Robert H.

“…Background & Aims: Patients with sphincter of Oddi dysfunction are at high risk of developing pancreatitis after endoscopic biliary sphincterotomy. Impaired…”
Get full text

Methodology of the Interventional Management of Stroke III Trial by Khatri, Pooja, Hill, Michael D., Palesch, Yuko Y., Spilker, Judith, Jauch, Edward C., Carrozzella, Janice A., Demchuk, Andrew M., Martin, Renee', Mauldin, Patrick, Dillon, Catherine, Ryckborst, Karla J., Janis, Scott, Tomsick, Thomas A., Broderick, Joseph P.

“…Rationale The Interventional Management of Stroke (IMS) I and II pilot trials demonstrated that the combined intravenous (i.v.) and intraarterial (i.a.)…”
Get full text

Statistical analysis plan for pooled individual patient data from two landmark randomized trials (INTERACT2 and ATACH-II) of intensive blood pressure lowering treatment in acute intracerebral hemorrhage by Moullaali, Tom J, Wang, Xia, Martin, Renee' H, Shipes, Virginia B, Qureshi, Adnan I, Anderson, Craig S, Palesch, Yuko Y

“…Background There is persistent uncertainty over the benefits of early intensive systolic blood pressure lowering in acute intracerebral hemorrhage. In…”
Get full text

Quantitative real‐time RT‐PCR detection of breast cancer micrometastasis using a multigene marker panel by Mitas, Michael, Mikhitarian, Kaidi, Walters, Christian, Baron, Paul L., Elliott, Bruce M., Brothers, Thomas E., Robison, Jay G., Metcalf, John S., Palesch, Yuko Y., Zhang, Zhen, Gillanders, William E., Cole, David J.

“…Real‐time RT‐PCR is a relatively new technology that uses an online fluorescence detection system to determine gene expression levels. It has the potential to…”
Get full text

Optimizing the ongoing search for new treatments for parkinson disease : Using futility designs by TILLEY, B. C, PALESCH, Y. Y, KIEBURTZ, K, RAVINA, B, HUANG, P, ELM, J. J, SHANNON, K, WOOTEN, G. F, TANNER, C. M, GOETZ, G. C

“…Many agents are being considered for treatment of Parkinson disease (PD). Given the large number of agents and the limited resources to evaluate new agents, it…”
Get full text