Search Results - "Palermo, Jorge A"

Antifouling Diterpenoids from the Sponge Dendrilla antarctica by Prieto, Iván M., Paola, Analía, Pérez, Miriam, García, Mónica, Blustein, Guillermo, Schejter, Laura, Palermo, Jorge A.

“…Two nor‐diterpenes, 9,11‐dihydrogracilin A (1) and the previously unreported 9,11‐dihydrogracillinone A (2), were isolated from the sponge Dendrilla…”
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Host cell cAMP-Epac-Rap1b pathway inhibition by hawthorn extract as a potential target against Trypanosoma cruzi infection by Ferri, Gabriel, Fernández, Lucía R, Di Mario, Guillermo, Musikant, Daniel, Palermo, Jorge A, Edreira, Martin M

“…Although the two drugs currently available for the treatment of Chagas disease, Benznidazole and Nifurtimox, have proven to be effective in the acute phase of…”
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Hybrids of Cinchona Alkaloids and Bile Acids as Antiparasitic Agents Against Trypanosoma cruzi by Musikant, Daniel, Leverrier, Aurélie, Bernal, Diana, Ferri, Gabriel, Palermo, Jorge A, Edreira, Martin M

“…The current chemotherapy of Chagas disease needs to be urgently improved. With this aim, a series of 16 hybrids of alkaloids and bile acids were prepared by…”
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Isolation and Antimacrofouling Activity of Indole and Furoquinoline Alkaloids from ‘Guatambú’ Trees (Aspidosperma australe and Balfourodendron riedelianum) by Pérez, Miriam, Pis Diez, Cristian M., Belén Valdez, María, García, Mónica, Paola, Analía, Avigliano, Esteban, Palermo, Jorge A., Blustein, Guillermo

“…In this work, the antifouling activity of five alkaloids, isolated from trees of the Atlantic rainforest, was studied. The tested alkaloids were olivacine (1),…”
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Preparation and antitrypanosomal activity of secochiliolide acid derivatives by Siless, Gastón E., Lozano, Esteban, Sánchez, Marianela, Mazzuca, Marcia, Sosa, Miguel A., Palermo, Jorge A.

“…Secochiliolide acid (1) isolated from the Patagonian shrub Nardophyllum bryoides, was used as a scaffold for the preparation of a series of nine derivatives…”
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Polyoxygenated steroids from the octocoral Leptogorgia punicea and in vitro evaluation of their cytotoxic activity by Moritz, Maria Izabel G, Marostica, Lucas Lourenço, Bianco, Everson M, Almeida, Maria Tereza R, Carraro, João L, Cabrera, Gabriela M, Palermo, Jorge A, Simões, Cláudia M O, Schenkel, Eloir P

“…Five new polyoxygenated marine steroids-punicinols A-E (1-5)-were isolated from the gorgonian Leptogorgia punicea and characterized by spectroscopic methods…”
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Unlocking the Potential of Glutinol: Structural Diversification and Antifungal Activity against Phytopathogenic Fusarium Strains by Belén Valdez, María, D′Jonsiles, María Fernanda, Avigliano, Esteban, Palermo, Jorge A.

“…Unlike most common pentacyclic plant triterpenes, glutinol has a methyl group at position C-9 and a Δ5 double bond. At the same time, it lacks a methyl at…”
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Target Fisher: a Consensus Structure-Based Target Prediction Tool, and its Application in the Discovery of Selective MAO-B Inhibitors by Fernández, Julián F, Heredia, Leandro Martinez, Caracciolo, Fernando, Esses, Daniel, Suarez, Rodrigo, Siless, Gaston, Perez, Concepcion, Rodríguez-Franco, María Isabel, Fernández, Lucía R, Palermo, Jorge A, Lavecchia, Martín

“…In this work we introduce Target Fisher, a consensus structure-based target prediction tool that integrates molecular docking and machine learning with the aim…”
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Illudalane Sesquiterpenoids from the Soft Coral Alcyonium paessleri:  The First Natural Nitrate Esters by Palermo, Jorge A, Rodríguez Brasco, Maria Florencia, Spagnuolo, Carla, Seldes, Alicia M

“…Fifteen illudalane sesquiterpenoids, alcyopterosins A−O (1−15) have been isolated from the subAntarctic soft coral Alcyonium paessleri which was collected at a…”
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Cytotoxic activity of semi-synthetic derivatives of elatol and isoobtusol by Lang, Karen L, Silva, Izabella T, Zimmermann, Lara A, Lhullier, Cíntia, Mañalich Arana, Maria V, Palermo, Jorge A, Falkenberg, Miriam, Simões, Cláudia M O, Schenkel, Eloir P, Durán, Fernando J

“…In the present study, the in vitro cytotoxic effects of six semi-synthetic derivatives of elatol (1) and isoobtusol (2) were investigated. Chemical…”
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Large-scale purification of pachydictyol A from the brown alga Dictyota dichotoma obtained from algal wash and evaluation of its antifouling activity against the freshwater mollusk Limnoperna fortunei by Siless, Gastón E., García, Mónica, Pérez, Miriam, Blustein, Guillermo, Palermo, Jorge A.

“…A scalable procedure was developed for the extraction and purification of pachydictyol A, the main diterpenoid isolated from the brown alga Dictyota dichotoma…”
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Antifouling activity of peracetylated cholic acid, a natural bile acid derivative by Pérez, Miriam, Sánchez, Marianela, García, Mónica, Patiño C., Laura P., Blustein, Guillermo, Palermo, Jorge A.

“…[Display omitted] •The antifouling activity of peracetylated cholic acid was evaluated in laboratory and field trials.•Peracetylated cholic acid had been…”
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Structure-activity relationship of hybrids of Cinchona alkaloids and bile acids with in vitro antiplasmodial and antitrypanosomal activities by Leverrier, Aurélie, Bero, Joanne, Cabrera, Julián, Frédérich, Michel, Quetin-Leclercq, Joëlle, Palermo, Jorge A.

“…In this work, a series of hybrid compounds were tested as antiparasitic substances. These hybrids were prepared from bile acids and a series of antiparasitic…”
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Synthesis and cytotoxicity evaluation of olivacine-indole hybrids tethered by alkyl linkers by Pis Diez, Cristian M., Céspedes, Mariela, Di Venosa, Gabriela M., Calvo, Gustavo, Avigliano, Esteban, Casas, Adriana G., Palermo, Jorge A.

“…In this work, eleven new derivatives were prepared of the alkaloid olivacine (1), which was isolated from the bark of Aspidosperma australe. These compounds…”
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Isolation and Antifouling Activity of Azulene Derivatives from the Antarctic Gorgonian Acanthogorgia laxa by Patiño Cano, Laura P., Quintana Manfredi, Rodrigo, Pérez, Miriam, García, Mónica, Blustein, Guillermo, Cordeiro, Ralf, Pérez, Carlos D., Schejter, Laura, Palermo, Jorge A.

“…Three azulenoid sesquiterpenes (1 – 3) were isolated from the Antarctic gorgonian Acanthogorgia laxa collected by bottom trawls at −343 m. Besides…”
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Bromopyrrole Alkaloids Isolated from the Patagonian Bryozoan Aspidostoma giganteum by Patiño C, Laura P, Muniain, Claudia, Knott, Maria Elena, Puricelli, Lydia, Palermo, Jorge A

“…Nine new bromopyrrole alkaloids, aspidostomides A–H and aspidazide A (1–9), were isolated from the Patagonian bryozoan Aspidostoma giganteum. Aspidostomides…”
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Antibacterial activity of extracts and compounds isolated from the Andean medicinal plant Azorella cryptantha (Clos) Reiche, Apiaceae by Lima, Beatriz, Sanchez, Marianela, Agüero, María Belén, Tapia, Alejandro, Palermo, Jorge A., Feresin, Gabriela Egly

“…•Azorella cryptantha a promising source of antimicrobial agents against enterobacteria Escherichia coli and Salmonella enteritidis.•Nine terpenes were isolated…”
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Secochiliolide ester derivatives: Preparation and evaluation of their antitrypanosomal and antimalarial efficacy by Ronchi, Romina J., Beaufay, Claire, Bero, Joanne, Robirosa, Juan B., Mazzuca, Marcia, Palermo, Jorge A., Quetin‐Leclercq, Joëlle, Sánchez, Marianela

“…In the present study, a series of new esters of secochiliolide acid (SA), a diterpene isolated from Nardophyllum bryoides, were synthesized in good yield. All…”
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Synthesis and antifungal activity of bile acid-derived oxazoles by Fernández, Lucía R., Svetaz, Laura, Butassi, Estefanía, Zacchino, Susana A., Palermo, Jorge A., Sánchez, Marianela

“…•Fourteen new bile acids oxazoles derivatives were synthesized.•The antifungal activity of the starting acids and the products was assayed.•The oxazole…”
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Antifungal Terpenoids from Hyalis argentea var. latisquama by Fernández, Lucía R, Butassi, Estefanía, Svetaz, Laura, Zacchino, Susana A, Palermo, Jorge A, Sánchez, Marianela

“…A detailed chemical study of the aerial parts and rhizomes of Hyalis argentea var. latisquama yielded a variety of sesqui- and diterpenes. In total, 26…”
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