Search Results - "Palek, Richard"
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A Double Edged Sword Role of Interleukin-22 in Wound Healing and Tissue Regeneration
Published in Frontiers in immunology (17-09-2020)“…Wound healing and tissue regeneration is an intricate biological process that involves repair of cellular damage and maintenance of tissue integrity. Cascades…”
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Prognostic role of macrophages and mast cells in the microenvironment of hepatocellular carcinoma after resection
Published in BMC cancer (29-01-2024)“…The prognostic significance of mast cells and different phenotypes of macrophages in the microenvironment of hepatocellular carcinoma (HCC) following resection…”
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3
Biomimetic hierarchical nanofibrous surfaces inspired by superhydrophobic lotus leaf structure for preventing tissue adhesions
Published in Materials & design (01-05-2022)“…[Display omitted] •The novel material was developed to prevent serious postoperative adhesions.•The large-scale fabrication was optimized, aiming towards a…”
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4
Porcine Liver Anatomy Applied to Biomedicine
Published in The Journal of surgical research (01-06-2020)“…Currently, there are at least 70 pure domestic pig breeds, but only certain breeds are used in biomedical research. The domestic pig liver is suitable for…”
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Why Use Position Features in Liver Segmentation Performed by Convolutional Neural Network
Published in Frontiers in physiology (01-10-2021)“…Liver volumetry is an important tool in clinical practice. The calculation of liver volume is primarily based on Computed Tomography. Unfortunately, automatic…”
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Protein expression of ABCC2 and SLC22A3 associates with prognosis of pancreatic adenocarcinoma
Published in Scientific reports (24-12-2019)“…ATP-binding cassette (ABC) and solute carrier (SLC) transporters translocate diverse substances across cellular membranes and their deregulation may cause drug…”
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Periphery of porcine hepatic lobes has the smallest length density of hepatic sinusoids and bile canaliculi: A stereological histological study with implications for liver biopsies
Published in Annals of anatomy (01-10-2023)“…Porcine liver is widely used in hepatologic research as a large animal model with many anatomical and physiological similarities with humans. However, only…”
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CTNNB1 mutations, TERT polymorphism and CD8+ cell densities in resected hepatocellular carcinoma are associated with longer time to recurrence
Published in BMC cancer (13-08-2022)“…Abstract Background Hepatocellular carcinoma (HCC) is a fatal disease characterized by early genetic alterations in telomerase reverse transcriptase promoter…”
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Mast Cells in the Microenvironment of Hepatocellular Carcinoma Confer Favorable Prognosis: A Retrospective Study using QuPath Image Analysis Software
Published in Journal of visualized experiments (12-04-2024)“…The insights provided by in-situ detection of immune cells within hepatocellular carcinoma (HCC) might present information on patient outcomes. Studies…”
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10
Stereological analysis of size and density of hepatocytes in the porcine liver
Published in Journal of anatomy (01-04-2017)“…The porcine liver is frequently used as a large animal model for verification of surgical techniques, as well as experimental therapies. Often, a histological…”
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11
Histological mapping of healing of the small and large intestine – A quantitative study in a porcine model
Published in Annals of anatomy (01-08-2023)“…Gastrointestinal anastomoses are performed in many patients every year. The pathogenesis of aberrant anastomotic healing and the causes of intestinal leakage…”
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12
Are ovine and porcine carotid arteries equivalent animal models for experimental cardiac surgery: A quantitative histological comparison
Published in Annals of anatomy (01-06-2022)“…Coronary artery bypass grafting (CABG) is a common cardiac surgery. Manufacturing small-diameter (2–5 mm) vascular grafts for CABG is important for patients…”
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T- and B-Cells in the Inner Invasive Margin of Hepatocellular Carcinoma after Resection Associate with Favorable Prognosis
Published in Cancers (25-01-2022)“…In this retrospective study on 67 patients with hepatocellular carcinoma (HCC), after tumor resection, we evaluated the significance of CD3+ and CD8+…”
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14
Novel morphological multi-scale evaluation system for quality assessment of decellularized liver scaffolds
Published in Journal of tissue engineering (2020)“…Decellularized scaffolds can serve as an excellent three-dimensional environment for cell repopulation. They maintain tissue-specific microarchitecture of…”
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15
Cross-species variability in lobular geometry and cytochrome P450 hepatic zonation: insights into CYP1A2, CYP2D6, CYP2E1 and CYP3A4
Published in Frontiers in pharmacology (16-05-2024)“…There is a lack of systematic research exploring cross-species variation in liver lobular geometry and zonation patterns of critical drug-metabolizing enzymes,…”
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Histological mapping of porcine carotid arteries — An animal model for the assessment of artificial conduits suitable for coronary bypass grafting in humans
Published in Annals of anatomy (01-03-2020)“…Using animal models in experimental medicine requires mapping of their anatomical variability. Porcine common carotid arteries (CCA) are often preferred for…”
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Porcine spleen as a model organ for blunt injury impact tests: An experimental and histological study
Published in Anatomia, histologia, embryologia (01-09-2022)“…The spleen is a large and highly vascularized secondary lymphatic organ. Spleen injuries are among the most frequent trauma‐related injuries in the abdominal…”
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Decellularized xenogeneic scaffolds in transplantation and tissue engineering: Immunogenicity versus positive cell stimulation
Published in Materials Science & Engineering C (01-08-2021)“…Seriously compromised function of some organs can only be restored by transplantation. Due to the shortage of human donors, the need to find another source of…”
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Small nucleolar RNA expression profiles: A potential prognostic biomarker for non-viral Hepatocellular carcinoma
Published in Non-coding RNA research (01-12-2024)“…Hepatocellular carcinoma (HCC) is a challenging cancer with high mortality rates, limited predictability, and a lack of effective prognostic indicators. The…”
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Large-Scale Development of Antibacterial Scaffolds: Gentamicin Sulfate-Loaded Biodegradable Nanofibers for Gastrointestinal Applications
Published in ACS omega (31-10-2023)“…The ever-increasing demands of modern medicine drive the development of novel drug delivery materials. In particular, nanofibers are promising for such…”
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