Search Results - "Palczewska, Malgorzata"
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Stimulators of mineralization limit the invasive phenotype of human osteosarcoma cells by a mechanism involving impaired invadopodia formation
Published in PloS one (14-10-2014)“…Osteosarcoma (OS) is a highly aggressive bone cancer affecting children and young adults. Growing evidence connects the invasive potential of OS cells with…”
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2
Data regarding a new, vector-enzymatic DNA fragment amplification-expression technology for the construction of artificial, concatemeric DNA, RNA and proteins, as well as biological effects of selected polypeptides obtained using this method
Published in Data in brief (01-02-2020)“…Applications of bioactive peptides and polypeptides are emerging in areas such as drug development and drug delivery systems. These compounds are bioactive,…”
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3
Neutralization of cholera toxin by Rosaceae family plant extracts
Published in BMC complementary and alternative medicine (20-06-2019)“…Cholera is one of the most deadly diarrheal diseases that require new treatments. We investigated the neutralization of cholera toxin by five plant extracts…”
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4
Diffusion nuclear magnetic resonance spectroscopy detects substoichiometric concentrations of small molecules in protein samples
Published in Analytical biochemistry (2010)“…Small molecules are difficult to detect in protein solutions, whether they originate from elution during affinity chromatography (e.g., imidazole, lactose),…”
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5
Characterization of calretinin I–II as an EF‐hand, Ca2+, H+‐sensing domain
Published in Protein science (01-07-2005)“…Calretinin, a neuronal protein with well‐defined calcium‐binding properties, has a poorly defined function. The pH dependent properties of calretinin (CR), the…”
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6
An efficient method for the construction of artificial, concatemeric DNA, RNA and proteins with genetically programmed functions, using a novel, vector-enzymatic DNA fragment amplification-expression technology
Published in MethodsX (01-01-2020)“…De novo designed bioactive molecules, such as DNA, RNA and peptides, are utilized in increasingly diverse scientific, industrial and biomedical applications…”
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7
Transcriptional repressor DREAM regulates trigeminal noxious perception
Published in Journal of neurochemistry (01-05-2017)“…Expression of the downstream regulatory element antagonist modulator (DREAM) protein in dorsal root ganglia and spinal cord is related to endogenous control…”
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8
Matrix vesicles isolated from mineralization-competent Saos-2 cells are selectively enriched with annexins and S100 proteins
Published in Biochemical and biophysical research communications (09-09-2011)“…► Functional MVs of Saos-2 cells are enriched in annexins A1, A2, A6 and A7. ► Some annexin levels in MVs change upon stimulation for mineralization. ► Annexin…”
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9
Temperature dependence of ligand-protein complex formation as reflected by saturation transfer difference NMR experiments
Published in Magnetic resonance in chemistry (01-09-2007)“…We show that temperature is an important parameter for the sensitivity of saturation transfer difference (STD) spectroscopy. A decreased intensity of STD…”
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10
Sumoylation regulates nuclear localization of repressor DREAM
Published in Biochimica et biophysica acta (01-05-2011)“…DREAM is a Ca2+-binding protein with specific functions in different cell compartments. In the nucleus, DREAM acts as a transcriptional repressor, although the…”
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Transcriptional repressor DREAM regulates T-lymphocyte proliferation and cytokine gene expression
Published in The EMBO journal (19-10-2005)“…Downstream Regulatory Element Antagonist Modulator (DREAM) is a Ca2+‐dependent transcriptional repressor expressed in the brain, thyroid gland and thymus…”
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12
Day-Night Changes in Downstream Regulatory Element Antagonist Modulator/Potassium Channel Interacting Protein Activity Contribute to Circadian Gene Expression in Pineal Gland
Published in The Journal of neuroscience (09-06-2004)“…The molecular mechanisms controlling the oscillatory synthesis of melatonin in rat pineal gland involve the rhythmic expression of several genes including…”
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A vector-enzymatic DNA fragment amplification-expression technology for construction of artificial, concatemeric DNA, RNA and proteins for novel biomaterials, biomedical and industrial applications
Published in Materials Science & Engineering C (01-03-2020)“…A DNA fragment amplification/expression technology for the production of new generation biomaterials for scientific, industrial and biomedical applications is…”
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14
Use of Pichia pastoris for the Expression, Purification, and Characterization of Rat Calretinin “EF-Hand” Domains
Published in Protein expression and purification (01-12-1999)“…Calretinin (CR) is a calcium-binding, neuronal protein of undefined function. Related proteins either buffer intracellular calcium concentrations or are…”
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15
Overexpressed yeast mitochondrial putative RNA helicase Mss116 partially restores proper mtRNA metabolism in strains lacking the Suv3 mtRNA helicase
Published in Yeast (Chichester, England) (01-11-2002)“…RNA helicase, encoded by the Saccharomyces cerevisiae nuclear gene SUV3, is a subunit of the mitochondrial (mt) degradosome: an enzyme complex that takes part…”
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Bacterial type AB₅ enterotoxins--structure, function and mechanism of action
Published in Postępy biochemii (2015)“…One of the main factors causing bacterial diarrhea are AB₅ enterotoxins. This group is divided into four families: pertussis toxin, cholera toxin, shiga toxin…”
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Use of plant extracts to control and treat AB5 enterotoxin-related diarrhea
Published in Polish journal of microbiology (2014)“…Plants contain a broad spectrum of small molecules with potential antimicrobial properties. Here, we review the antimicrobial activities of plant extracts…”
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S100A proteins in propagation of a calcium signal in norm and pathology
Published in Postępy biochemii (2012)“…Calcium ions are essential factors controlling the balance between cell survival, growth, differentiation and metabolism. Ca2+ acts as a global second…”
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Structural and biochemical characterization of neuronal calretinin domain I-II (residues 1-100). Comparison to homologous calbindin D28k domain I-II (residues 1-93)
Published in European journal of biochemistry (01-12-2001)“…This study characterizes the calcium-bound CR I-II domain (residues 1-100) of rat calretinin (CR). CR, with six EF-hand motifs, is believed to function as a…”
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20
Characterization of calretinin I–II as an EF‐hand, Ca 2+ , H + ‐sensing domain
Published in Protein science (01-07-2005)“…Abstract Calretinin, a neuronal protein with well‐defined calcium‐binding properties, has a poorly defined function. The pH dependent properties of calretinin…”
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