Search Results - "Palazzo, Robert"
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William R. Brinkley: A giant in biomedical research and public policy
Published in The Journal of cell biology (04-10-2021)“…Susan A. Gerbi, Robert E. Palazzo, William C. Earnshaw, and William T. Schrader discuss the life and achievements of William R. Brinkley, who passed away on…”
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Cardiac Myosin Inhibition for Treatment of LVOT Obstruction in a Patient With Severe AS
Published in JACC. Case reports (03-07-2024)“…Aortic stenosis and obstructive hypertrophic cardiomyopathy are common conditions. When both are present in the same patient, the management can be…”
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Centrosome-Associated RNA in Surf Clam Oocytes
Published in Proceedings of the National Academy of Sciences - PNAS (13-06-2006)“…Centrosomes are the major microtubule-organizing center in animal cells. They are composed of a pair of [9(3) + 0] centrioles surrounded by a relatively…”
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Aurora-A Kinase Regulates Breast Cancer-Associated Gene 1 Inhibition of Centrosome-Dependent Microtubule Nucleation
Published in Cancer research (Chicago, Ill.) (01-12-2007)“…Breast cancer-associated gene 1 (BRCA1) regulates the duplication and the function of centrosomes in breast cells. We have previously shown that BRCA1…”
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BRCA1 regulates γ-tubulin binding to centrosomes
Published in Cancer biology & therapy (01-12-2007)“…Centrosomes are the cellular organelles that nucleate microtubules (MTs) via the activity of gamma-tubulin ring complex(s) (γ-TuRC) bound to the pericentriolar…”
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Characterization of Cep135, a Novel Coiled-Coil Centrosomal Protein Involved in Microtubule Organization in Mammalian Cells
Published in The Journal of cell biology (07-01-2002)“…By using monoclonal antibodies raised against isolated clam centrosomes, we have identified a novel 135-kD centrosomal protein (Cep135), present in a wide…”
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Rapid Tau Aggregation and Delayed Hippocampal Neuronal Death Induced by Persistent Thrombin Signaling
Published in The Journal of biological chemistry (26-09-2003)“…Tau hyperphosphorylation, leading to self-aggregation, is widely held to underlie the neurofibrillary degeneration found in Alzheimer's disease (AD) and other…”
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Acute surgical pulmonary embolectomy: a 9-year retrospective analysis
Published in Texas Heart Institute journal (01-02-2015)“…Acute pulmonary embolism is a substantial cause of morbidity and death. Although the American College of Chest Physicians Evidence-Based Clinical Practice…”
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The Disassembly and Reassembly of Functional Centrosomes in Vitro
Published in Proceedings of the National Academy of Sciences - PNAS (04-08-1998)“…Animal cells contain a single centrosome that nucleates and organizes a polarized array of microtubules which functions in many cellular processes. In most…”
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The small organic compound HMN-176 delays satisfaction of the spindle assembly checkpoint by inhibiting centrosome-dependent microtubule nucleation
Published in Molecular cancer therapeutics (01-03-2009)“…HMN-176 is a potential new cancer therapeutic known to retard the proliferation of tumor cell lines. Here, we show that this compound inhibits meiotic spindle…”
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Cyclin E/Cdk2 is required for sperm maturation, but not DNA replication, in early sea urchin embryos
Published in Genesis (New York, N.Y. : 2000) (01-05-2007)“…The cell cycle is driven by the activity of cyclin/cdk complexes. In somatic cells, cyclin E/cdk2 oscillates throughout the cell cycle and has been shown to…”
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What's happening to the new investigator?
Published in The FASEB journal (01-07-2006)Get full text
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Effect of γ-synuclein overexpression on matrix metalloproteinases in retinoblastoma Y79 cells
Published in Archives of biochemistry and biophysics (01-02-2003)“…γ-Synuclein is a small cytoplasmic protein implicated in neurodegenerative diseases and cancer. However, the mechanism of its involvement in diseases is not…”
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Centrosomes and spindle pole bodies
Published 2001“…Containing a comprehensive collection of convenient and quantitative methods for studying centrosomes, spindle pole bodies and related organelles, this text is…”
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Using centrosome fragments in the directed assembly of microtubules
Published in Journal of nanoscience and nanotechnology (01-02-2009)“…In animal cells, microtubules are organized by centrosomes, which are 1-2 microm diameter organelles. The generation of functional centrosome fragments…”
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Warming up at the poles: Workshop on Centrosomes and Spindle Pole Bodies
Published in EMBO reports (01-04-2006)Get full text
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Differential Regulation of Maternal vs. Paternal Centrosomes
Published in Proceedings of the National Academy of Sciences - PNAS (16-02-1999)“…Centrosomes are the main microtubule-organizing centers in animal cells. During meiosis and mitosis, two centrosomes form the poles that direct the assembly of…”
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Direct patterning of centrosome arrays as templates for the assembly of microtubules
Published in Biotechnology and bioengineering (05-08-2006)“…We have achieved, for the first time, the selective patterning of centrosomes onto solid substrates. The use of such patterned centrosome arrays as templates…”
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Giant aneurysm of saphenous vein graft to coronary artery compressing the right atrium
Published in The Annals of Thoracic Surgery (01-10-1999)“…Aneurysm of reverse aortocoronary saphenous vein graft is a known complication of coronary artery bypass grafting. In this report we present a case of a…”
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Spontaneous Right Ventricular Disruption Following Treatment of Sternal Infection
Published in Journal of cardiac surgery (01-01-2004)“…Background: Spontaneous right ventricular disruption is a rare and frequently catastrophic event that occurs during the treatment of mediastinitis complicating…”
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