Search Results - "Palazzo, Isabella"

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    Reactive microglia and IL1β/IL-1R1-signaling mediate neuroprotection in excitotoxin-damaged mouse retina by Todd, Levi, Palazzo, Isabella, Suarez, Lilianna, Liu, Xiaoyu, Volkov, Leo, Hoang, Thanh V, Campbell, Warren A, Blackshaw, Seth, Quan, Ning, Fischer, Andy J

    Published in Journal of neuroinflammation (06-06-2019)
    “…Microglia and inflammation have context-specific impacts upon neuronal survival in different models of central nervous system (CNS) disease. Herein, we…”
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    Journal Article
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    Common and divergent gene regulatory networks control injury-induced and developmental neurogenesis in zebrafish retina by Lyu, Pin, Iribarne, Maria, Serjanov, Dmitri, Zhai, Yijie, Hoang, Thanh, Campbell, Leah J., Boyd, Patrick, Palazzo, Isabella, Nagashima, Mikiko, Silva, Nicholas J., Hitchcock, Peter F., Qian, Jiang, Hyde, David R., Blackshaw, Seth

    Published in Nature communications (20-12-2023)
    “…Following acute retinal damage, zebrafish possess the ability to regenerate all neuronal subtypes through Müller glia (MG) reprogramming and asymmetric cell…”
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    Journal Article
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    mTor signaling is required for the formation of proliferating Müller glia-derived progenitor cells in the chick retina by Zelinka, Christopher P, Volkov, Leo, Goodman, Zachary A, Todd, Levi, Palazzo, Isabella, Bishop, William A, Fischer, Andy J

    Published in Development (Cambridge) (01-06-2016)
    “…We investigate the roles of mTor signaling in the formation of Müller glia-derived progenitor cells (MGPCs) in the chick retina. During embryonic development,…”
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    Journal Article
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    Patterns of NFkB activation resulting from damage, reactive microglia, cytokines, and growth factors in the mouse retina by Palazzo, Isabella, Kelly, Lisa, Koenig, Lindsay, Fischer, Andy J.

    Published in Experimental neurology (01-01-2023)
    “…Müller glia are a cellular source for neuronal regeneration in vertebrate retinas. However, the capacity for retinal regeneration varies widely across species…”
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    Journal Article
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    NF-κB signaling regulates the formation of proliferating Müller glia-derived progenitor cells in the avian retina by Palazzo, Isabella, Deistler, Kyle, Hoang, Thanh V, Blackshaw, Seth, Fischer, Andy J

    Published in Development (Cambridge) (22-05-2020)
    “…Retinal regeneration is robust in some cold-blooded vertebrates, but this process is ineffective in warm-blooded vertebrates. Understanding the mechanisms that…”
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    Journal Article
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    NF-κB signaling regulates the formation of proliferating Müller glia-derived progenitor cells in the avian retina by Palazzo, Isabella, Deistler, Kyle, Hoang, Thanh V, Blackshaw, Seth, Fischer, Andy J

    Published in Development (Cambridge) (01-05-2020)
    “…Retinal regeneration is robust in some cold-blooded vertebrates, but this process is ineffective in warm-blooded vertebrates. Understanding the mechanisms that…”
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    Journal Article
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    NFkB‐signaling promotes glial reactivity and suppresses Müller glia‐mediated neuron regeneration in the mammalian retina by Palazzo, Isabella, Todd, Levi J., Hoang, Thanh V., Reh, Thomas A., Blackshaw, Seth, Fischer, Andy J.

    Published in Glia (01-07-2022)
    “…Müller glia (MG) in mammalian retinas are incapable of regenerating neurons after damage, whereas the MG in lower vertebrates regenerate functional neurons…”
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    Journal Article
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    BMP‐ and TGFβ‐signaling regulate the formation of Müller glia‐derived progenitor cells in the avian retina by Todd, Levi, Palazzo, Isabella, Squires, Natalie, Mendonca, Ninoshka, Fischer, Andy J.

    Published in Glia (01-10-2017)
    “…Müller glia‐derived progenitor cells (MGPCs) have the capability to regenerate neurons in the retinas of different vertebrate orders. The formation of MGPCs is…”
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    Journal Article
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    Midkine is neuroprotective and influences glial reactivity and the formation of Müller glia‐derived progenitor cells in chick and mouse retinas by Campbell, Warren A., Fritsch‐Kelleher, Amanda, Palazzo, Isabella, Hoang, Thanh, Blackshaw, Seth, Fischer, Andy J.

    Published in Glia (01-06-2021)
    “…Recent studies suggest midkine (MDK) is involved in the development and regeneration of the zebrafish retina. We investigate the expression patterns of MDK and…”
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    Journal Article
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    Regulating the formation of Müller glia-derived progenitor cells in the retina by Taylor, Olivia B, El-Hodiri, Heithem M, Palazzo, Isabella, Todd, Levi, Fischer, Andy J

    Published in Glia (24-10-2024)
    “…We summarize recent findings in different animal models regarding the different cell-signaling pathways and gene networks that influence the reprogramming of…”
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    Journal Article
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    Wnt/β‐catenin‐signaling and the formation of Müller glia‐derived progenitors in the chick retina by Gallina, Donika, Palazzo, Isabella, Steffenson, Lillia, Todd, Levi, Fischer, Andy J.

    Published in Developmental neurobiology (Hoboken, N.J.) (01-09-2016)
    “…ABSTRACT Müller glia can be stimulated to de‐differentiate, proliferate, and form Müller glia‐derived progenitor cells (MGPCs) that are capable of producing…”
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    Journal Article
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    Modulation of Neuroinflammatory Signaling Enhances the Neurogenic Reprogramming Capacity of Müller Glia across Species by Palazzo, Isabella

    Published 01-01-2021
    “…Retinal degeneration is a leading cause of blindness. Progressive death of retinal neurons is irreversible and results in loss of vision. Currently, there are…”
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    Dissertation
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    Robust reprogramming of glia into neurons by inhibition of Notch signaling and nuclear factor I (NFI) factors in adult mammalian retina by Le, Nguyet, Vu, Trieu-Duc, Palazzo, Isabella, Pulya, Ritvik, Kim, Yehna, Blackshaw, Seth, Hoang, Thanh

    Published in Science advances (12-07-2024)
    “…Generation of neurons through direct reprogramming has emerged as a promising therapeutic approach for treating neurodegenerative diseases. In this study, we…”
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    Journal Article
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    IRS2 increases mitochondrial dysfunction and oxidative stress in a mouse model of Huntington disease by Sadagurski, Marianna, Cheng, Zhiyong, Rozzo, Aldo, Palazzolo, Isabella, Kelley, Gregory R, Dong, Xiaocheng, Krainc, Dimitri, White, Morris F

    Published in The Journal of clinical investigation (01-10-2011)
    “…Aging is a major risk factor for the progression of neurodegenerative diseases, including Huntington disease (HD). Reduced neuronal IGF1 or Irs2 signaling have…”
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    Journal Article