Search Results - "Palazzo, Alberta"

The Role of Transglutaminase 2 in Cancer: An Update by Zaltron, Elisabetta, Vianello, Federica, Ruzza, Alessia, Palazzo, Alberta, Brillo, Valentina, Celotti, Ilaria, Scavezzon, Matteo, Rossin, Federica, Leanza, Luigi, Severin, Filippo

“…Transglutaminase type 2 (TG2) is the most ubiquitously expressed and well characterized member of the transglutaminase family. It is a ubiquitous…”
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Germline duplication of ATG2B and GSKIP predisposes to familial myeloid malignancies by Saliba, Joseph, Saint-Martin, Cécile, Di Stefano, Antonio, Lenglet, Gaëlle, Marty, Caroline, Keren, Boris, Pasquier, Florence, Valle, Véronique Della, Secardin, Lise, Leroy, Gwendoline, Mahfoudhi, Emna, Grosjean, Sarah, Droin, Nathalie, Diop, M'boyba, Dessen, Philippe, Charrier, Sabine, Palazzo, Alberta, Merlevede, Jane, Meniane, Jean-Côme, Delaunay-Darivon, Christine, Fuseau, Pascal, Isnard, Françoise, Casadevall, Nicole, Solary, Eric, Debili, Najet, Bernard, Olivier A, Raslova, Hana, Najman, Albert, Vainchenker, William, Bellanné-Chantelot, Christine, Plo, Isabelle

“…Isabelle Plo, Christine Bellanné-Chantelot, William Vainchenker and colleagues report a 700-kb germline duplication including the ATG2B and GSKIP genes in four…”
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Critical role of the HDAC6–cortactin axis in human megakaryocyte maturation leading to a proplatelet-formation defect by Messaoudi, Kahia, Ali, Ashfaq, Ishaq, Rameez, Palazzo, Alberta, Sliwa, Dominika, Bluteau, Olivier, Souquère, Sylvie, Muller, Delphine, Diop, Khadija M., Rameau, Philippe, Lapierre, Valérie, Marolleau, Jean-Pierre, Matthias, Patrick, Godin, Isabelle, Pierron, Gérard, Thomas, Steven G., Watson, Stephen P., Droin, Nathalie, Vainchenker, William, Plo, Isabelle, Raslova, Hana, Debili, Najet

“…Thrombocytopenia is a major side effect of a new class of anticancer agents that target histone deacetylase (HDAC). Their mechanism is poorly understood. Here,…”
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Crucial Role for Endoplasmic Reticulum Stress During Megakaryocyte Maturation by Lopez, Jose J, Palazzo, Alberta, Chaabane, Chiraz, Albarran, Letizia, Polidano, Evelyne, Lebozec, Kristell, Dally, Saoussen, Nurden, Paquita, Enouf, Jocelyne, Debili, Najet, Bobe, Régis

“…OBJECTIVE—Apoptotic-like phase is an essential step for the platelet formation from megakaryocytes. How controlled is this signaling pathway remained poorly…”
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Transglutaminase type 2 modulates melanoma mitochondrial metabolism during phenotype switching by Vianello, Federica, Zaltron, Elisabetta, Ruzza, Alessia, Palazzo, Alberta, Brillo, Valentina, Severin, Filippo, Leanza, Luigi

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Impaired Mitochondrial Metabolism And Er-Mitochondria Contact Sites Affect Signaling In Cancer Cells by Zaltron, Elisabetta, Severin, Filippo, Ruzza, Alessia, Vianello, Federica, Palazzo, Alberta, Brillo, Valentina, Leanza, Luigi

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Transformed cells after senescence give rise to more severe tumor phenotypes than transformed non-senescent cells by Palazzo, Alberta, Hernandez-Vargas, Hector, Goehrig, Delphine, Médard, Jean-Jacques, Vindrieux, David, Flaman, Jean-Michel, Bernard, David

“…Oncogenic stress-induced senescence initially inhibits tumor initiation by blocking proliferation and by attracting immune cells to clear potentially harmful…”
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Benidipine calcium channel blocker promotes the death of cigarette smoke-induced senescent cells and improves lung emphysema by Palazzo, Alberta, Makulyte, Gabriela, Goerhig, Delphine, Médard, Jean-Jacques, Gros, Vincent, Trottein, François, Adnot, Serge, Vindrieux, David, Flaman, Jean-Michel, Bernard, David

“…Smoking is the main risk factor for many lung diseases including chronic obstructive pulmonary disease. Cigarette smoke (CS) contains carcinogenic and reactive…”
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Transformed cells after senescence give rise to more severe tumor phenotypes than transformed non-senescent cells by Palazzo, Alberta, Hernandez-Vargas, Hector, Goehrig, Delphine, Médard, Jean-Jacques, Vindrieux, David, Flaman, Jean-Michel, Bernard, David

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The antioxidant N-acetylcysteine protects from lung emphysema but induces lung adenocarcinoma in mice by Breau, Marielle, Houssaini, Amal, Lipskaia, Larissa, Abid, Shariq, Born, Emmanuelle, Marcos, Elisabeth, Czibik, Gabor, Attwe, Aya, Beaulieu, Delphine, Palazzo, Alberta, Flaman, Jean-Michel, Bourachot, Brigitte, Collin, Guillaume, Tran Van Nhieu, Jeanne, Bernard, David, Mechta-Grigoriou, Fatima, Adnot, Serge

“…Oxidative stress is a major contributor to chronic lung diseases. Antioxidants such as N-acetylcysteine (NAC) are broadly viewed as protective molecules that…”
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Critical role of the HDAC6–cortactin axis in human megakaryocyte maturation leading to a proplatelet-formation defect by Messaoudi, Kahia, Ali, Ashfaq, Ishaq, Rameez, Palazzo, Alberta, Sliwa, Dominika, Bluteau, Olivier, Souquère, Sylvie, Muller, Delphine, Diop, Khadija, Rameau, Philippe, Lapierre, Valérie, Marolleau, Jean-Pierre, Matthias, Patrick, Godin, Isabelle, Pierron, Gérard, Thomas, Steven, Watson, Stephen, Droin, Nathalie, Vainchenker, William, Plo, Isabelle, Raslova, Hana, Debili, Najet

“…Abstract Thrombocytopenia is a major side effect of a new class of anticancer agents that target histone deacetylase (HDAC). Their mechanism is poorly…”
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Abstract 2022: P53-dependent thrombocytopenia induced by the histone deacetylase inhibitor S78454 by Ali, Ashfaq, Bluteau, Olivier, Palazzo, Alberta, Boukour, Siham, Lordier, Larissa, Rameau, Philippe, Leceluse, Yann, Kraus-Berthier, Laurence, Jacquet-Bescond, Anne, Lelièvre, Hélène, Depil, Stéphane, Solary, Eric, Raslova, Hana, Vainchenker, William, Plo, Isabelle, DEBILI, Najet

“…Abstract S78454 (also called PCI-24781) is an orally bioavailable, hydroxamate-based pan-HDACi currently being tested in clinical trials in the US and EU. Like…”
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Abnormal Proplatelet Formation and Myosin Activation Status in Patients with MYH9-Related Syndrome by Chen, Yolande, Boukour, Siham, Nurden, Paquita, Seye, Ababacar, Bluteau, Olivier, Palazzo, Alberta, Chang, Yunhua, Lordier, Larissa, Favier, Remi, Schlegel, Nicole, Galy, Anne, Nurden, Alan T., Raslova, Hana, Vainchenker, William, Debili, Najet

“…Abstract 4826 MYH9-related disorders (MYH9-RD) are characterized by an autosomal-dominant macrothrombocytopenia associated or not with glomerular impairment,…”
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