Search Results - "Palazon‐Riquelme, Pablo"
-
1
The inflammasomes, immune guardians at defence barriers
Published in Immunology (01-11-2018)“…Summary As a result of its strategic location, the epithelium is constantly exposed to a wide variety of pathogen and danger signals. Traditionally, the…”
Get full text
Journal Article -
2
NLRP3 at the crossroads between immune/inflammatory responses and enteric neuroplastic remodelling in a mouse model of diet‐induced obesity
Published in British journal of pharmacology (01-10-2021)“…Background and Purpose Enteric neurogenic/inflammation contributes to bowel dysmotility in obesity. We examined the role of NLRP3 in colonic neuromuscular…”
Get full text
Journal Article -
3
Pathophysiology of NSAID-Associated Intestinal Lesions in the Rat: Luminal Bacteria and Mucosal Inflammation as Targets for Prevention
Published in Frontiers in pharmacology (29-11-2018)“…Non-steroidal anti-inflammatory drugs (NSAIDs) can damage the small intestine, mainly through an involvement of enteric bacteria. This study examined the…”
Get full text
Journal Article -
4
USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation
Published in EMBO reports (01-10-2018)“…The assembly and activation of the inflammasomes are tightly regulated by post‐translational modifications, including ubiquitin. Deubiquitinases (DUBs)…”
Get full text
Journal Article -
5
Prodromal Intestinal Events in Alzheimer's Disease (AD): Colonic Dysmotility and Inflammation Are Associated with Enteric AD-Related Protein Deposition
Published in International journal of molecular sciences (15-05-2020)“…Increasing evidence suggests that intestinal dysfunctions may represent early events in Alzheimer's disease and contribute to brain pathology. This study…”
Get full text
Journal Article -
6
Method to Measure Ubiquitination of NLRs
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2016)“…Posttranslational modifications are crucial in determining the functions of proteins in the cell. Modification of the NLRP3 inflammasome by the ubiquitin…”
Get more information
Journal Article -
7
Method to Measure Ubiquitination of NLRs
Published in Methods in molecular biology (Clifton, N.J.) (2023)“…Posttranslational modifications are crucial in determining the functions of proteins in the cell. Modification of the NLRP3 inflammasome by the ubiquitin…”
Get more information
Journal Article -
8
The three cytokines IL-1β, IL-18, and IL-1α share related but distinct secretory routes
Published in The Journal of biological chemistry (24-05-2019)“…Interleukin (IL)-1 family cytokines potently regulate inflammation, with the majority of the IL-1 family proteins being secreted from immune cells via…”
Get full text
Journal Article -
9
Mechanisms and Consequences of Inflammasome Activation
Published 01-01-2017“…Inflammation is the response of the body to injury or threats. Immune cells such as macrophages have a crucial role in controlling and regulating this process…”
Get full text
Dissertation