Search Results - "Palanisamy, Karthikka"
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Optimization of an in vitro bilayer model for studying the functional interplay between human primary retinal pigment epithelial and choroidal endothelial cells isolated from donor eyes
Published in BMC research notes (30-05-2019)“…The microenvironment of outer retina is largely regulated by retinal pigment epithelium (RPE) and choroid. Damage to either of these layers lead to the…”
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Adiponectin-induced activation of ERK1/2 drives fibrosis in retinal pigment epithelial cells
Published in Human cell : official journal of Human Cell Research Society (26-10-2024)“…Adiponectin (APN), a vasoactive cytokine produced by adipocytes, has emerged as a critical player in retinal diseases. Renowned for its antioxidant,…”
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Anti-angiogenic effect of adiponectin in human primary microvascular and macrovascular endothelial cells
Published in Microvascular research (01-03-2019)“…Neovascularization in retina and choroid involves interplay of many cytokines and growth factors. Vascular endothelial growth factor (VEGF) being a…”
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Adiponectin: A potential candidate for treating fibrosis in posterior segment of the eye
Published in Medical hypotheses (01-02-2019)“…Fibrosis in ocular tissues causes severe visual deterioration and blindness in patients with glaucoma, cataract, age related macular degeneration (AMD) and…”
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Possible role of HIWI2 in modulating tight junction proteins in retinal pigment epithelial cells through Akt signaling pathway
Published in Molecular and cellular biochemistry (01-03-2017)“…PIWI subfamily of proteins is shown to be primarily expressed in germline cells. They maintain the genomic integrity by silencing the transposable elements…”
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