Search Results - "Palanisamy, Arulselvan"
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A review on advanced microencapsulation technology to enhance bioavailability of phenolic compounds: Based on its activity in the treatment of Type 2 Diabetes
Published in Trends in food science & technology (01-03-2019)“…Studies on and the application of polyphenolic compounds, have recently attracted great interest in the functional foods due to their potential health benefits…”
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Role of Antioxidants and Natural Products in Inflammation
Published in Oxidative medicine and cellular longevity (01-01-2016)“…Inflammation is a comprehensive array of physiological response to a foreign organism, including human pathogens, dust particles, and viruses. Inflammations…”
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Fabrication of folic acid-embedded aminated drug encapsulated zeolitic imidazolate framework as promising drug delivery system for lung cancer
Published in Journal of materials research (28-05-2024)“…A novel pH-responsive drug carrier for the delivery of specific Docetaxel (DTX) administration is developed based on a zeolitic imidazolate framework (ZIF-8)…”
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Phytobioactive compound-based nanodelivery systems for the treatment of type 2 diabetes mellitus - current status
Published in International Journal of Nanomedicine (01-01-2017)“…Type 2 diabetes mellitus (T2DM) is a major chronic disease that is prevalent worldwide, and it is characterized by an increase in blood glucose, disturbances…”
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Moringa oleifera Flower Extract Suppresses the Activation of Inflammatory Mediators in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages via NF-κB Pathway
Published in Mediators of inflammation (01-01-2015)“…Aim of Study. Moringa oleifera Lam. (M. oleifera) possess highest concentration of antioxidant bioactive compounds and is anticipated to be used as an…”
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Dual drug co‐encapsulation of bevacizumab and pemetrexed clocked polymeric nanoparticles improves antiproliferative activity and apoptosis induction in liver cancer cells
Published in Journal of applied polymer science (15-12-2024)“…Nanoparticle (NP) enabled approaches have been employed for chemotherapeutic administration due to their capacity to regulate drug release and reduce side…”
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Chlorambucil-Iron Oxide Nanoparticles as a Drug Delivery System for Leukemia Cancer Cells
Published in International journal of nanomedicine (01-01-2021)“…Traditional cancer therapies may have incomplete eradication of cancer or destroy the normal cells. Nanotechnology solves the demerit by a guide in surgical…”
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In Vitro Wound Healing Potential of Stem Extract of Alternanthera sessilis
Published in Evidence-based complementary and alternative medicine (01-01-2018)“…Impaired wound healing is one of the serious problems among the diabetic patients. Currently, available treatments are limited due to side effects and cost…”
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Facile construction of gefitinib‐loaded zeolitic imidazolate framework nanocomposites for the treatment of different lung cancer cells
Published in Biotechnology and applied biochemistry (01-08-2024)“…Gefitinib (GET) is a revolutionary targeted treatment inhibiting the epidermal growth factor receptor's tyrosine kinase action by competitively inhibiting the…”
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Identification of Bioactive Candidate Compounds Responsible for Oxidative Challenge from Hydro-Ethanolic Extract of Moringa oleifera Leaves
Published in Journal of food science (01-09-2013)“…Free radicals trigger chain reaction and inflict damage to the cells and its components, which in turn ultimately interrupts their biological activities. To…”
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Healing Effect of Vicenin-2 (VCN-2) on Human Dermal Fibroblast (HDF) and Development VCN-2 Hydrocolloid Film Based on Alginate as Potential Wound Dressing
Published in BioMed research international (2020)“…Chronic wounds represent serious globally health care and economic issues especially for patients with hyperglycemic condition. Wound dressings have a…”
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Suppression of Proinflammatory Cytokines and Mediators in LPS-Induced RAW 264.7 Macrophages by Stem Extract of Alternanthera sessilis via the Inhibition of the NF-κB Pathway
Published in Journal of immunology research (01-01-2018)“…Alternanthera sessilis, an edible succulent herb, has been widely used as herbal drug in many regions around the globe. Inflammation is a natural process of…”
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The in vitro therapeutic activity of betulinic acid nanocomposite on breast cancer cells (MCF-7) and normal fibroblast cell (3T3)
Published in Journal of materials science (01-12-2014)“…In the present study, magnetic nanoparticles (MNPs) were coated with chitosan (CS) polymer to form CS–MNP nanoparticles. The CS–MNP were loaded with an…”
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Pemetrexed loaded gold nanoparticles as cytotoxic and apoptosis inducers in lung cancer cells through ROS generation and mitochondrial dysfunction pathway
Published in Biotechnology and applied biochemistry (01-08-2024)“…Supramolecular nanoparticles containing peptides and drugs have recently gained recognition as an effective tumor treatment drug delivery system. A multitarget…”
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Anti-Inflammatory Potential of Ethyl Acetate Fraction of Moringa oleifera in Downregulating the NF-κB Signaling Pathway in Lipopolysaccharide-Stimulated Macrophages
Published in Molecules (Basel, Switzerland) (31-10-2016)“…In the present investigation, we prepared four different solvent fractions (chloroform, hexane, butanol, and ethyl acetate) of extract to evaluate its…”
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Comparison of Phytochemicals, Antioxidant and Anti-Inflammatory Properties of Sun-, Oven- and Freeze-Dried Ginger Extracts
Published in Foods (06-10-2019)“…The effects of different drying methods, including sun-, oven-, and freeze-drying on the changes in the antioxidant and anti-inflammatory activities of ginger…”
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In Vitro Wound Healing Potential and Identification of Bioactive Compounds from Moringa oleifera Lam
Published in BioMed research international (01-01-2013)“…Moringa oleifera Lam. (M. oleifera) from the monogeneric family Moringaceae is found in tropical and subtropical countries. The present study was aimed at…”
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Development of a novel anti-tuberculosis nanodelivery formulation using magnesium layered hydroxide as the nanocarrier and pyrazinamide as a model drug
Published in Scientific reports (18-08-2022)“…Designing and synthesizing biodegradable drug delivery systems are key research areas in biomedical nanotechnology. Here, we report the development of…”
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Efficiency of newly formulated camptothecin with β-cyclodextrin-EDTA-Fe3O4 nanoparticle-conjugated nanocarriers as an anti-colon cancer (HT29) drug
Published in Scientific reports (08-09-2017)“…Camptothecin (CPT) is an anti-cancer drug that effectively treats various cancers, including colon cancer. However, poor solubility and other drawbacks have…”
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Arbutin exerts anticancer activity against rat C6 glioma cells by inducing apoptosis and inhibiting the inflammatory markers and P13/Akt/mTOR cascade
Published in Journal of biochemical and molecular toxicology (01-09-2021)“…Gliomas are a type of brain cancer that occurs in the supporting glial cells of the brain. It is highly malignant and accounts for 80% of brain tumors with…”
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