Search Results - "Palanimuthu, Duraippandi"

Structure–Activity Relationships of Di-2-pyridylketone, 2‑Benzoylpyridine, and 2‑Acetylpyridine Thiosemicarbazones for Overcoming Pgp-Mediated Drug Resistance by Stacy, Alexandra E, Palanimuthu, Duraippandi, Bernhardt, Paul V, Kalinowski, Danuta S, Jansson, Patric J, Richardson, Des R

“…Multidrug resistance (MDR) mediated by P-glycoprotein (Pgp) represents a significant impediment to successful cancer treatment. The compound,…”
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Biotin Decorated Gold Nanoparticles for Targeted Delivery of a Smart-Linked Anticancer Active Copper Complex: In Vitro and In Vivo Studies by Pramanik, Anup K, Siddikuzzaman, Palanimuthu, Duraippandi, Somasundaram, Kumaravel, Samuelson, Ashoka G

“…The synthesis and anticancer activity of a copper­(II) diacetyl-bis­(N4-methylthiosemicarbazone) complex and its nanoconjugates are reported. The copper­(II)…”
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Imaging Intracellular Zinc by Using a Glyoxal Bis(4-methyl-4-phenyl-3-thiosemicarbazone) Ligand by Palanimuthu, Duraippandi, Shinde, Sridevi Vijay, Dayal, Disha, Somasundaram, Kumaravel, Samuelson, Ashoka G.

“…The ligand glyoxal bis(4‐methyl‐4‐phenyl‐3‐thiosemicarbazone) (GTSCH2) is shown to be a selective fluorescence “turn‐on” sensor for zinc ions (Zn2+). This…”
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In Vitro and in Vivo Anticancer Activity of Copper Bis(thiosemicarbazone) Complexes by Palanimuthu, Duraippandi, Shinde, Sridevi Vijay, Somasundaram, Kumaravel, Samuelson, Ashoka G

“…Neutral and cationic copper bis(thiosemicarbazone) complexes bearing methyl, phenyl, and hydrogen, on the diketo-backbone of the ligand have been synthesized…”
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Synthesis, Characterization, and in Vitro Anticancer Activity of Copper and Zinc Bis(Thiosemicarbazone) Complexes by Anjum, Rukhsana, Palanimuthu, Duraippandi, Kalinowski, Danuta S, Lewis, William, Park, Kyung Chan, Kovacevic, Zaklina, Khan, Irfan Ullah, Richardson, Des R

“…A series of eight bis­(thiosemicarbazone) ligands and 16 of their respective copper­(II) and zinc­(II) complexes containing a combination of hydrogen, methyl,…”
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Dinuclear zinc bis(thiosemicarbazone) complexes: Synthesis, in vitro anticancer activity, cellular uptake and DNA interaction study by Palanimuthu, Duraippandi, Samuelson, Ashoka G.

“…A series of new dinuclear zinc complexes based on bis(thiosemicarbazone) ligands has been synthesized. Their anticancer activity was screened against five…”
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Zinc(II)–Thiosemicarbazone Complexes Are Localized to the Lysosomal Compartment Where They Transmetallate with Copper Ions to Induce Cytotoxicity by Stacy, Alexandra E, Palanimuthu, Duraippandi, Bernhardt, Paul V, Kalinowski, Danuta S, Jansson, Patric J, Richardson, Des R

“…As the di-2-pyridylketone thiosemicarbazone (DpT) and 2-acetylpyridine thiosemicarbazone (ApT) series show potent antitumor activity in vitro and in vivo, we…”
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Electrocatalytic Oxidation of Hydrazine Using a Cobalt Bis(thiosemicarbazone) Complex by Marichelvam, Thamaraichelvan, Murugan, Ganapathi, Holla, Harish, Naranammalpuram Sundaram, Venkata Narayanan, Palanimuthu, Duraippandi

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Inhibition and kinetic studies of phytochemical constituents of Goniothalamus wynaadensis and their isoxazoline derivatives on α-glucosidase by Bojja, Kavya Sritha, Kumar, Akash, Palanimuthu, Duraippandi, Holla, Harish, Gawli, Kavishankar

“…α-Glucosidase, an enzyme involved in post-prandial hyperglycaemia, was used as a target to study the effect of compound(s) isolated from and its isoxazoline…”
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A novel class of thiosemicarbazones show multi-functional activity for the treatment of Alzheimer's disease by Palanimuthu, Duraippandi, Poon, Rachal, Sahni, Sumit, Anjum, Rukhsana, Hibbs, David, Lin, Hsuan-Yu, Bernhardt, Paul V., Kalinowski, Danuta S., Richardson, Des R.

“…Over 44 million people live with Alzheimer's disease (AD) worldwide. Currently, only symptomatic treatments are available for AD and no cure exists…”
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Copper and conquer: copper complexes of di-2-pyridylketone thiosemicarbazones as novel anti-cancer therapeutics by Park, Kyung Chan, Fouani, Leyla, Jansson, Patric J, Wooi, Danson, Sahni, Sumit, Lane, Darius J. R, Palanimuthu, Duraippandi, Lok, Hiu Chuen, Kova evi, Zaklina, Huang, Michael L. H, Kalinowski, Danuta S, Richardson, Des R

“…Copper is an essential trace metal required by organisms to perform a number of important biological processes. Copper readily cycles between its reduced Cu( i…”
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Novel multifunctional iron chelators of the aroyl nicotinoyl hydrazone class that markedly enhance cellular NAD+/NADH ratios by Wu, Zhixuan, Palanimuthu, Duraippandi, Braidy, Nady, Salikin, Nor Hawani, Egan, Suhelen, Huang, Michael L.H., Richardson, Des R.

“…Background and Purpose Alzheimer's disease (AD) is a multifactorial condition leading to cognitive decline and represents a major global health challenge in…”
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A novel zinc bis(thiosemicarbazone) complex for live cell imaging by Dayal, Disha, Palanimuthu, Duraippandi, Shinde, Sridevi Vijay, Somasundaram, Kumaravel, Samuelson, Ashoka G.

“…Fluorescent zinc complexes have recently attracted a lot of interest owing to their vast applications in cellular imaging. We report the synthesis as well as…”
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The use of iron chelators in biocidal compositions: evaluation of patent, WO2014059417A1 by Sahni, Sumit, Krishan, Sukriti, Palanimuthu, Duraippandi, Richardson, Des R

“…Anti-microbial-potentiating compositions, containing one or more anti-microbial agents and an iron chelator, are claimed in the patent application. Different…”
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