Search Results - "Palacio, José Pérez"

Metabolomic profile of cancer stem cell‐derived exosomes from patients with malignant melanoma by Palacios‐Ferrer, José Luis, García‐Ortega, María Belén, Gallardo‐Gómez, María, García, María Ángel, Díaz, Caridad, Boulaiz, Houria, Valdivia, Javier, Jurado, José Miguel, Almazan‐Fernandez, Francisco M., Arias‐Santiago, Salvador, Amezcua, Víctor, Peinado, Héctor, Vicente, Francisca, Pérez del Palacio, José, Marchal, Juan A.

“…Malignant melanoma (MM) is the most aggressive form of skin cancer, with increasing incidence worldwide. To date, there are no suitable clinical diagnostic,…”
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Untargeted Metabolomics for the Diagnosis of Exocrine Pancreatic Insufficiency in Chronic Pancreatitis by Díaz, Caridad, Jiménez-Luna, Cristina, Diéguez-Castillo, Carmelo, Martín, Ariadna, Prados, José, Martín-Ruíz, José Luis, Genilloud, Olga, Vicente, Francisca, Pérez del Palacio, José Pérez del, Caba, Octavio

“…Background and Objectives: The clinical manifestations and course of chronic pancreatitis (CP) are often nonspecific and variable, hampering diagnosis of the…”
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Discovery of Pancreatic Adenocarcinoma Biomarkers by Untargeted Metabolomics by Martín-Blázquez, Ariadna, Jiménez-Luna, Cristina, Díaz, Caridad, Martínez-Galán, Joaquina, Prados, Jose, Vicente, Francisca, Melguizo, Consolación, Genilloud, Olga, Pérez Del Palacio, José, Caba, Octavio

“…Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and lethal cancers, with a 5-year survival rate of less than 5%. In fact, complete…”
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The antifungal activity and mechanisms of action of quantified extracts from berries, leaves and roots of Phytolacca tetramera by Butassi, Estefanía, Svetaz, Laura A., Zhou, Shuaizhen, Wolfender, Jean-Luc, Cortés, Juan C.G., Ribas, Juan C., Díaz, Caridad, Palacio, José Pérez-del, Vicente, Francisca, Zacchino, Susana A.

“…Phytolacca tetramera is an endemic plant from Argentina that is currently at serious risk because its environment is subjected to a high anthropic impact. A…”
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Human Plasma Metabolomics for Biomarker Discovery: Targeting the Molecular Subtypes in Breast Cancer by Díaz-Beltrán, Leticia, González-Olmedo, Carmen, Luque-Caro, Natalia, Díaz, Caridad, Martín-Blázquez, Ariadna, Fernández-Navarro, Mónica, Ortega-Granados, Ana Laura, Gálvez-Montosa, Fernando, Vicente, Francisca, Pérez Del Palacio, José, Sánchez-Rovira, Pedro

“…The aim of this study is to identify differential metabolomic signatures in plasma samples of distinct subtypes of breast cancer patients that could be used in…”
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Insights into the Pharmacokinetics and In Vitro Cell-Based Studies of the Imidazoline I2 Receptor Ligand B06 by Bagán, Andrea, Morales-García, José A., Griñán-Ferré, Christian, Díaz, Caridad, Pérez del Palacio, José, Ramos, Maria C., Vicente, Francisca, Pérez, Belén, Brea, José, Loza, María Isabel, Pallàs, Mercè, Escolano, Carmen

“…The impact of neurodegenerative diseases (ND) is becoming unbearable for humankind due to their vast prevalence and the lack of efficacious treatments. In this…”
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Identification of Compounds with Potential Therapeutic Uses from Sweet Pepper ( Capsicum annuum L.) Fruits and Their Modulation by Nitric Oxide (NO) by Guevara, Lucía, Domínguez-Anaya, María Ángeles, Ortigosa, Alba, González-Gordo, Salvador, Díaz, Caridad, Vicente, Francisca, Corpas, Francisco J, Pérez Del Palacio, José, Palma, José M

“…Plant species are precursors of a wide variety of secondary metabolites that, besides being useful for themselves, can also be used by humans for their…”
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Preclinical evaluation of strasseriolides A–D, potent antiplasmodial macrolides isolated from Strasseria geniculata CF-247,251 by Annang, Frederick, Pérez-Moreno, Guiomar, Díaz, Caridad, González-Menéndez, Victor, de Pedro Montejo, Nuria, del Palacio, José Pérez, Sánchez, Paula, Tanghe, Scott, Rodriguez, Ana, Pérez-Victoria, Ignacio, Cantizani, Juan, Ruiz-Pérez, Luis M, Genilloud, Olga, Reyes, Fernando, Vicente, Francisca, González-Pacanowska, Dolores

“…Background Malaria is a global health problem for which novel therapeutic compounds are needed. To this end, a recently published novel family of…”
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Untargeted LC-HRMS-based metabolomics to identify novel biomarkers of metastatic colorectal cancer by Martín-Blázquez, Ariadna, Díaz, Caridad, González-Flores, Encarnación, Franco-Rivas, Daniel, Jiménez-Luna, Cristina, Melguizo, Consolación, Prados, José, Genilloud, Olga, Vicente, Francisca, Caba, Octavio, Pérez del Palacio, José

“…Colorectal cancer is one of the main causes of cancer death worldwide, and novel biomarkers are urgently needed for its early diagnosis and treatment. The…”
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The Antioxidant Properties of Lavandula multifida Extract Contribute to Its Beneficial Effects in High-Fat Diet-Induced Obesity in Mice by Molina-Tijeras, Jose Alberto, Ruiz-Malagón, Antonio Jesús, Hidalgo-García, Laura, Diez-Echave, Patricia, Rodríguez-Sojo, María Jesús, Cádiz-Gurrea, María de la Luz, Segura-Carretero, Antonio, Del Palacio, José Pérez, González-Tejero, María Reyes, Rodríguez-Cabezas, María Elena, Gálvez, Julio, Rodríguez-Nogales, Alba, Vezza, Teresa, Algieri, Francesca

“…Obesity is a worldwide public health problem whose prevalence rate has increased steadily over the last few years. Therefore, it is urgent to improve the…”
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Predicting dynamic response to neoadjuvant chemotherapy in breast cancer: a novel metabolomics approach by Díaz, Caridad, González‐Olmedo, Carmen, Díaz‐Beltrán, Leticia, Camacho, José, Mena García, Patricia, Martín‐Blázquez, Ariadna, Fernández‐Navarro, Mónica, Ortega‐Granados, Ana Laura, Gálvez‐Montosa, Fernando, Marchal, Juan Antonio, Vicente, Francisca, Pérez del Palacio, José, Sánchez‐Rovira, Pedro

“…Neoadjuvant chemotherapy (NACT) outcomes vary according to breast cancer (BC) subtype. Since pathologic complete response is one of the most important target…”
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High-Throughput Screening Platform for the Discovery of New Immunomodulator Molecules from Natural Product Extract Libraries by Pérez Del Palacio, José, Díaz, Caridad, de la Cruz, Mercedes, Annang, Frederick, Martín, Jesús, Pérez-Victoria, Ignacio, González-Menéndez, Víctor, de Pedro, Nuria, Tormo, José R, Algieri, Francesca, Rodriguez-Nogales, Alba, Rodríguez-Cabezas, M Elena, Reyes, Fernando, Genilloud, Olga, Vicente, Francisca, Gálvez, Julio

“…It is widely accepted that central nervous system inflammation and systemic inflammation play a significant role in the progression of chronic…”
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Zebrafish-Based Discovery of Antiseizure Compounds from the Red Sea: Pseurotin A2 and Azaspirofuran A by Copmans, Daniëlle, Rateb, Mostafa, Tabudravu, Jioji N, Pérez-Bonilla, Mercedes, Dirkx, Nina, Vallorani, Riccardo, Diaz, Caridad, Pérez del Palacio, José, Smith, Alan J, Ebel, Rainer, Reyes, Fernando, Jaspars, Marcel, de Witte, Peter A. M

“…In search for novel antiseizure drugs (ASDs), the European FP7-funded PharmaSea project used zebrafish embryos and larvae as a drug discovery platform to…”
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Anti-inflammatory activity of hydroalcoholic extracts of Lavandula dentata L. and Lavandula stoechas L by Algieri, Francesca, Rodriguez-Nogales, Alba, Vezza, Teresa, Garrido-Mesa, Jose, Garrido-Mesa, Natividad, Utrilla, M. Pilar, González-Tejero, M. Reyes, Casares-Porcel, Manuel, Molero-Mesa, Joaquin, del Mar Contreras, Maria, Segura-Carretero, Antonio, Pérez-Palacio, José, Diaz, Caridad, Vergara, Noemí, Vicente, Francisca, Rodriguez-Cabezas, M. Elena, Galvez, Julio

“…Plants from genus Lavandula have been used as anti-inflammatory drugs in Mediterranean traditional medicine. Nowadays, there is a growing interest for…”
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Exploring the Role of CYP3A4 Mediated Drug Metabolism in the Pharmacological Modulation of Nitric Oxide Production by Pérez-Del Palacio, José, Díaz, Caridad, Vergara, Noemí, Algieri, Francesca, Rodríguez-Nogales, Alba, de Pedro, Nuria, Rodríguez-Cabezas, M Elena, Genilloud, Olga, Gálvez, Julio, Vicente, Francisca

“…Nitric-oxide synthase, the enzyme responsible for mammalian nitric oxide generation, and cytochrome P450, the major enzymes involved in drug metabolism, share…”
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Comparative Metabolomics between Mycobacterium tuberculosis and the MTBVAC Vaccine Candidate by Díaz, Caridad, Pérez del Palacio, José, Valero-Guillén, Pedro Luis, Mena García, Patricia, Pérez, Irene, Vicente, Francisca, Martín, Carlos, Genilloud, Olga, Sánchez Pozo, Antonio, Gonzalo-Asensio, Jesús

“…MTBVAC is a live attenuated M. tuberculosis vaccine constructed by genetic deletions in the phoP and fadD26 virulence genes. The MTBVAC vaccine is currently in…”
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Untargeted LC-HRMS-Based Metabolomics for Searching New Biomarkers of Pancreatic Ductal Adenocarcinoma: A Pilot Study by Ríos Peces, Sandra, Díaz Navarro, Caridad, Márquez López, Cristina, Caba, Octavio, Jiménez-Luna, Cristina, Melguizo, Consolación, Prados, José Carlos, Genilloud, Olga, Vicente Pérez, Francisca, Pérez Del Palacio, José

“…Pancreatic ductal adenocarcinoma is one of the most lethal tumors since it is usually detected at an advanced stage in which surgery and/or current…”
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O -Alkyl Hydroxamates Display Potent and Selective Antileishmanial Activity by Corpas-López, Victoriano, Tabraue-Chávez, Mavys, Sixto-López, Yudibeth, Panadero-Fajardo, Sonia, Alves de Lima Franco, Fernando, Domínguez-Seglar, José F, Morillas-Márquez, Francisco, Franco-Montalbán, Francisco, Díaz-Gavilán, Mónica, Correa-Basurto, José, López-Viota, Julián, López-Viota, Margarita, Pérez Del Palacio, José, de la Cruz, Mercedes, de Pedro, Nuria, Martín-Sánchez, Joaquina, Gómez-Vidal, José A

“…( ) causes visceral, cutaneous, and mucosal leishmaniasis in humans and canine leishmaniasis in dogs. Herein, we describe that -alkyl hydroxamate derivatives…”
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Systemic blockade of LPA1/3 lysophosphatidic acid receptors by ki16425 modulates the effects of ethanol on the brain and behavior by Sánchez-Marín, Laura, Ladrón de Guevara-Miranda, David, Mañas-Padilla, M. Carmen, Alén, Francisco, Moreno-Fernández, Román D., Díaz-Navarro, Caridad, Pérez-del Palacio, José, García-Fernández, María, Pedraza, Carmen, Pavón, Francisco J., Rodríguez de Fonseca, Fernando, Santín, Luis J., Serrano, Antonia, Castilla-Ortega, Estela

“…The systemic administration of lysophosphatidic acid (LPA) LPA1/3 receptor antagonists is a promising clinical tool for cancer, sclerosis and fibrosis-related…”
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Identification of novel biomarkers in the early diagnosis of malignant melanoma by untargeted liquid chromatography coupled to high-resolution mass spectrometry-based metabolomics: a pilot study by Peña-Martín, Jesús, Belén García-Ortega, María, Palacios-Ferrer, José Luis, Díaz, Caridad, Ángel García, María, Boulaiz, Houria, Valdivia, Javier, Jurado, José Miguel, Almazan-Fernandez, Francisco M, Arias Santiago, Salvador, Vicente, Francisca, Del Val, Coral, Pérez Del Palacio, José, Marchal, Juan Antonio

“…Malignant melanoma (MM) is a highly aggressive form of skin cancer whose incidence continues to rise worldwide. If diagnosed at an early stage, it has an…”
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