Search Results - "Pala Kara, Zeliha"
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The role of pharmacists in the management of autism spectrum disorder: A survey to determine the knowledge and perception of the parents
Published in Istanbul journal of pharmacy (01-12-2019)“…Autism spectrum disorder (ASD) is one of the neuropsychiatric disorders of childhood and has many causes including genetic, neurobiological, environmental, as…”
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Evaluation of the association of SNP in carboxylesterase enzyme (CES1) with pharmacokinetic and adverse effects of capecitabine in breast and colorectal cancer patients
Published in Istanbul journal of pharmacy (01-08-2019)“…Capecitabine is an oral prodrug and converted to 5-fluorouracil using three-step enzymatic pathways which include carboxylesterase (CES). Interindividual…”
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The effects of P-glycoprotein inhibitor zosuquidar on the sex and time-dependent pharmacokinetics of parenterally administered talinolol in mice
Published in European journal of pharmaceutical sciences (01-01-2021)“…P-glycoprotein (P-gp) is an efflux protein that forms a tissue barrier and plays a role in the pharmacokinetics of drugs, limiting the influx of them and other…”
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4
Dosing-time dependent testicular toxicity of everolimus in mice
Published in European journal of pharmaceutical sciences (01-10-2021)“…The circadian timing system controls many biological functions in mammals including drug metabolism and detoxification, cell cycle events, and thus may affect…”
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Dosing‐time, feeding, and sex‐dependent variations of everolimus pharmacokinetics in mice
Published in Fundamental & clinical pharmacology (01-10-2024)“…Background Everolimus is an oral mammalian target of rapamycin (mTOR) inhibitor used as an immunosuppressant and anticancer. Its pharmacokinetics is highly…”
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Diurnal Changes in Capecitabine Clock-Controlled Metabolism Enzymes Are Responsible for Its Pharmacokinetics in Male Mice
Published in Journal of biological rhythms (01-04-2023)“…The circadian timing system controls absorption, distribution, metabolism, and elimination processes of drug pharmacokinetics over a 24-h period. Exposure of…”
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Association between ABCB1, ABCG2 carrier protein and COX-2 enzyme gene polymorphisms and breast cancer risk in a Turkish population
Published in Saudi pharmaceutical journal (01-02-2020)“…Breast cancer is the most common cancer and the second leading cause of cancer-related deaths among women. Several genetic and environmental factors are known…”
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Association Between Human Telomerase Reverse Transcriptase Gene Variations and Risk of Developing Breast Cancer
Published in Genetic testing and molecular biomarkers (01-08-2016)“…Despite a reduction in the number of deaths from cancers made possible by the development of early detection tests, improvements in treatment, changes in the…”
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Chronomodulated oxaliplatin plus Capecitabine (XELOX) as a first line chemotherapy in metastatic colorectal cancer: A Phase II Brunch regimen study
Published in Cancer chemotherapy and pharmacology (01-07-2016)“…Purpose The aim of this study was to evaluate safety and toxicity of chronomodulated capecitabine administered in the morning and at noon according to a…”
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The effect of terpenes on percutaneous absorption of tiaprofenic acid gel
Published in Archives of pharmacal research (01-11-2010)“…Tiaprofenic acid is a potent analgesic and nonsteroidal anti-inflammatory drug (NSAID) and like any other nonsteroidal anti-inflammatory drug, oral…”
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Carbon tetrachloride-induced kidney damage and protective effect of Amaranthus lividus L. in rats
Published in Toxicology and industrial health (01-06-2016)“…This study was designed to evaluate the protective effect of water extract of Amaranthus lividus L. (A. lividus) (Amaranthaceae) on carbon tetrachloride…”
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The immune system as a chronotoxicity target of the anticancer mTOR inhibitor everolimus
Published in Chronobiology international (04-05-2018)“…The circadian timing system controls many biological functions in mammals including xenobiotic metabolism, detoxification, cell proliferation, apoptosis and…”
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Chronomodulated Administration of Oxaliplatin plus Capecitabine (XELOX) as First Line Chemotherapy in Metastatic Colorectal Cancer Patients: Phase II Brunch Regimen Study
Published in Journal of clinical oncology (20-05-2015)“…Abstract only…”
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Protective effect of Amaranthus lividus L. on carbon tetrachloride induced hepatotoxicity in rats / Karbon tetraklorür ile sıçanlarda oluşturulan karaciğer toksisitesi üzerine Amaranthus lividus L. bitkisinin koruyucu etkisi
Published in Turkish Journal of Biochemistry (01-04-2015)“…Objective: Amaranthus lividus is consumed as popular vegetable in West Black Sea Region of Turkey. In this study, we aimed to evaluate the protective and…”
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Protective effect of Amaranthus lividus L. on carbon tetrachloride induced hepatotoxicity in rats
Published in Turkish Journal of Biochemistry (2015)Get full text
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