Search Results - "Pal, Gian D"

Medication only improves limb movements while deep brain stimulation improves eye and limb movements during visually-guided reaching in Parkinson's disease by Munoz, Miranda J, Arora, Rishabh, Rivera, Yessenia M, Drane, Quentin H, Pal, Gian D, Verhagen Metman, Leo, Sani, Sepehr B, Rosenow, Joshua M, Goelz, Lisa C, Corcos, Daniel M, David, Fabian J

“…Antiparkinson medication and subthalamic nucleus deep brain stimulation (STN-DBS), two common treatments of Parkinson's disease (PD), effectively improve…”
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Medication improves velocity, reaction time, and movement time but not amplitude or error during memory‐guided reaching in Parkinson's disease by Trevarrow, Michael P., Munoz, Miranda J., Rivera, Yessenia M., Arora, Rishabh, Drane, Quentin H., Pal, Gian D., Verhagen Metman, Leonard, Goelz, Lisa C., Corcos, Daniel M., David, Fabian J.

“…The motor impairments experienced by people with Parkinson's disease (PD) are exacerbated during memory‐guided movements. Despite this, the effect of…”
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Encoding type, medication, and deep brain stimulation differentially affect memory-guided sequential reaching movements in Parkinson's disease by David, Fabian J, Rivera, Yessenia M, Entezar, Tara K, Arora, Rishabh, Drane, Quentin H, Munoz, Miranda J, Rosenow, Joshua M, Sani, Sepehr B, Pal, Gian D, Verhagen-Metman, Leonard, Corcos, Daniel M

“…Memory-guided movements, vital to daily activities, are especially impaired in Parkinson's disease (PD). However, studies examining the effects of how…”
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Subthalamic Peak Beta Ratio Is Asymmetric in Glucocerebrosidase Mutation Carriers With Parkinson's Disease: A Pilot Study by David, Fabian J, Munoz, Miranda J, Shils, Jay L, Pauciulo, Michael W, Hale, Philip T, Nichols, William C, Afshari, Mitra, Sani, Sepehr, Verhagen Metman, Leo, Corcos, Daniel M, Pal, Gian D

“…Up to 27% of individuals undergoing subthalamic nucleus deep brain stimulation (STN-DBS) have a genetic form of Parkinson's disease (PD). G ( ) mutation…”
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Validating the targets for neurostimulation in essential tremor by Weiss, Daniel, Pal, Gian D

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Cognitive Effects of Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease with GBA1 Pathogenic Variants by Pal, Gian D., Corcos, Daniel M., Metman, Leo Verhagen, Israel, Zvi, Bergman, Hagai, Arkadir, David

“…Genetic subtyping of patients with Parkinson's disease (PD) may assist in predicting the cognitive and motor outcomes of subthalamic deep brain stimulation…”
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Benefits of subthalamic nucleus deep brain stimulation on visually-guided saccades depend on stimulation side and classic paradigm in Parkinson’s disease by Munoz, Miranda J., Reilly, James L., Pal, Gian D., Verhagen Metman, Leo, Sani, Sepehr B., Rosenow, Joshua M., Rivera, Yessenia M., Drane, Quentin H., Goelz, Lisa C., Corcos, Daniel M., David, Fabian J.

“…•Right unilateral STN-DBS is not significantly different from OFF stimulation at impacting rightward saccades.•Left unilateral and bilateral STN-DBS benefit…”
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Medication adversely impacts visually-guided eye movements in Parkinson’s disease by Munoz, Miranda J., Reilly, James L., Pal, Gian D., Verhagen Metman, Leo, Rivera, Yessenia M., Drane, Quentin H., Corcos, Daniel M., David, Fabian J., Goelz, Lisa C.

“…•Saccade latency is prolonged as disease severity increases, irrespective of whether participants were off or on medication.•Medication effects interact with…”
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Subthalamic Physiology in Genetic Subtypes of Parkinson's Disease by Pal, Gian D., David, Fabian J., Shils, Jay L., Munoz, Miranda J., Afshari, Mitra, Sani, Sepehr, Verhagen Metman, Leo, Corcos, Daniel M.

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Comparison of neuropathology in Parkinson's disease subjects with and without deep brain stimulation by Pal, Gian D., Ouyang, Bichun, Serrano, Geidy, Shill, Holly A., Goetz, Christopher, Stebbins, Glenn, Metman, Leo Verhagen, Driver‐Dunckley, Erika, Mehta, Shyamal H., Caviness, John N., Sabbagh, Marwan N., Adler, Charles H., Beach, Thomas G.

“…ABSTRACT Background: The aim of this postmortem study was to compare, in Parkinson's disease subjects with and without bilateral subthalamic nucleus deep brain…”
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Abnormal lipopolysaccharide binding protein as marker of gastrointestinal inflammation in Parkinson disease by Pal, Gian D, Shaikh, Maliha, Forsyth, Christopher B, Ouyang, Bichun, Keshavarzian, Ali, Shannon, Kathleen M

“…An inflammation-driven model of PD has been proposed based on the endotoxin lipopolysaccaride (LPS), a potential source of inflammation in the gastrointestinal…”
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The Effects of Subthalamic Nucleus Deep Brain Stimulation and Retention Delay on Memory-Guided Reaching Performance in People with Parkinson’s Disease by Trevarrow, Michael P., Munoz, Miranda J., Rivera, Yessenia M., Arora, Rishabh, Drane, Quentin H., Rosenow, Joshua M., Sani, Sepehr B., Pal, Gian D., Verhagen Metman, Leonard, Goelz, Lisa C., Corcos, Daniel M., David, Fabian J.

“…Background: Subthalamic nucleus deep brain stimulation (STN-DBS) improves intensive aspects of movement (velocity) in people with Parkinson’s disease (PD) but…”
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Motor Evoked Potential Recordings During Segmented Deep Brain Stimulation—A Feasibility Study by Shils, Jay, Kochanski, Ryan B, Borghei, Alireza, Candocia, Alexander, Pal, Gian D, Afshari, Mitra, Verhagen, Leonard Metman, Sani, Sepehr

“…Abstract BACKGROUND Segmented deep brain stimulation (DBS) leads, which are capable of steering current in the direction of any 1 of 3 segments, can result in…”
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Muscle Contraction as a False Localizing Sign During Intraoperative Macrostimulation of Subthalamic Nucleus by Pal, Gian D., Sani, Sepehr, Verhagen, Leo

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Genetic and Clinical Predictors of Deep Brain Stimulation in Young-Onset Parkinson's Disease by Pal, Gian D., Hall, Deborah, Ouyang, Bichun, Phelps, Jessica, Alcalay, Roy, Pauciulo, Michael W., Nichols, William C., Clark, Lorraine, Mejia-Santana, Helen, Blasucci, Lucia, Goetz, Christopher G., Comella, Cynthia, Colcher, Amy, Gan-Or, Ziv, Rouleau, Guy A., Marder, Karen

“…Objective In a cohort of patients with young‐onset Parkinson's disease (PD), the authors assessed (1) the prevalence of genetic mutations in those who enrolled…”
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The Core Assessment Program for Surgical Interventional Therapies in Parkinson's Disease (CAPSIT‐PD): Tolerability of Preoperative Neuropsychological Testing for Deep Brain Stimulation in Parkinson's Disease by Pal, Gian D., Persinger, Virginia, Bernard, Bryan, Ouyang, Bichun, Goetz, Christopher G., Verhagen Metman, Leo

“…Objective We examined tolerability of preoperative neuropsychological testing (the Core Assessment Program for Surgical Interventional Therapies in Parkinson's…”
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Subthalamic physiology in genetic subtypes of Parkinson disease by Pal, Gian D., David, Fabian J., Shils, Jay L., Munoz, Miranda J., Afshari, Mitra, Sani, Sepehr, Metman, Leo Verhagen, Corcos, Daniel M.

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The commercial genetic testing landscape for Parkinson's disease by Cook, Lola, Schulze, Jeanine, Verbrugge, Jennifer, Beck, James C., Marder, Karen S., Saunders-Pullman, Rachel, Klein, Christine, Naito, Anna, Alcalay, Roy N., Brice, Alexis, Kumeh, Amasi, West, Andrew B., Singleton, Andrew, Naito, Anna, Schüle, Birgitt, Fiske, Brian, Gabbert, Carolin, Marras, Connie, Blauwendraat, Cornelis, Thaxton, Courtney, Alessi, Dario, Craig, David, Fon, Edward A., Forbes, Emily, Valente, Enza Maria, Sammler, Esther, Chao, Gill, Riboldi, Giulietta, Elloumi, Houda Zghal, Mata, Ignacio, Beck, James C., Fong, Jamie C., Corvol, Jean-Christophe, Schulze, Jeanine, Verbrugge, Jennifer, Shulman, Joshua, Peterschmitt, Judith, Marder, Karen, Lohmann, Katja, Nudelman, Kelly, Lange, Lara, Cook, Lola, Cookson, Mark R., Nance, Martha, Farrer, Matthew, Grigorian, Melina, Schwarzschild, Michael A., Mencacci, Niccolo, Ross, Owen, Mistry, Pramod, Hodges, Priscila, Blake, Rachel, Saunders-Pullman, Rachel, Alcalay, Roy N., Sardi, S. Pablo, Farhan, Sali, Strom, Samuel, Padmanabhan, Shalini, Mohan, Shruthi, Longerich, Simonne, Schneider, Susanne, Lesage, Suzanne, Bardakjian, Tanya, Foroud, Tatiana, Courtin, Thomas, Tropea, Thomas, Liu, Yunlong, Gan-Or, Ziv, Shalash, Ali S., Hall, Anne, Thaler, Avner, Sue, Carolyn M., Mascalzoni, Deborah, Raymond, Deborah, Gatto, Emilia Mabel, Pal, Gian D., König, Inke, Novakovic, Ivana, Merello, Marcelo, Salari, Mehri, Mencacci, Niccolo Emanuele, Hattori, Nobutaka, Suchowersky, Oksana, Bardien, Soraya, Chung, Sun Ju, Simuni, Tatyana, Lynch, Timothy, Bonifati, Vincenzo

“…There have been no specific guidelines regarding which genes should be tested in the clinical setting for Parkinson's disease (PD) or parkinsonism. We…”
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Comparison of neuropathology in Parkinson's disease subjects with and without deep brain stimulation: Neuropathology In Pd With and Without DBS by Pal, Gian D., Ouyang, Bichun, Serrano, Geidy, Shill, Holly A., Goetz, Christopher, Stebbins, Glenn, Metman, Leo Verhagen, Driver-Dunckley, Erika, Mehta, Shyamal H., Caviness, John N., Sabbagh, Marwan N., Adler, Charles H., Beach, Thomas G.

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Optimization of Microelectrode Recording in DBS Surgery Using Intraoperative CT by Kochanski, Ryan B., MD, Bus, Sander, MD, Pal, Gian, MD, Metman, Leo Verhagen, MD, PhD, Sani, Sepehr, MD

“…Abstract Background Microelectrode recording (MER) is used to confirm targeting accuracy during deep brain stimulation (DBS) surgery. We describe a technique…”
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