Search Results - "Pal, Gian"

Validating the targets for neurostimulation in essential tremor by Weiss, Daniel, Pal, Gian D

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Cognitive Effects of Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease with GBA1 Pathogenic Variants by Pal, Gian D., Corcos, Daniel M., Metman, Leo Verhagen, Israel, Zvi, Bergman, Hagai, Arkadir, David

“…Genetic subtyping of patients with Parkinson's disease (PD) may assist in predicting the cognitive and motor outcomes of subthalamic deep brain stimulation…”
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Reliability, feasibility and satisfaction of telemedicine evaluations for cervical dystonia by Fraint, Avram, Stebbins, Glenn T, Pal, Gian, Comella, Cynthia L

“…Telemedicine is used successfully for evaluating patients with neurologic diseases, but has not been tested in cervical dystonia (CD). CD is uniquely suited…”
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Impact of a 2-week flipped classroom virtual neurology clerkship versus a traditional 4-week rotation on NBME shelf exam scores by Rybinnik, Igor, Pal, Gian, Farrukh, Humza, Deverett, Ben, Przydzial, Paulina, Mani, Ram

“…Objective There is conflicting evidence whether decreased clerkship duration is associated with reduced NBME shelf examination performance. We hypothesized…”
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Benefits of subthalamic nucleus deep brain stimulation on visually-guided saccades depend on stimulation side and classic paradigm in Parkinson’s disease by Munoz, Miranda J., Reilly, James L., Pal, Gian D., Verhagen Metman, Leo, Sani, Sepehr B., Rosenow, Joshua M., Rivera, Yessenia M., Drane, Quentin H., Goelz, Lisa C., Corcos, Daniel M., David, Fabian J.

“…•Right unilateral STN-DBS is not significantly different from OFF stimulation at impacting rightward saccades.•Left unilateral and bilateral STN-DBS benefit…”
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Medication adversely impacts visually-guided eye movements in Parkinson’s disease by Munoz, Miranda J., Reilly, James L., Pal, Gian D., Verhagen Metman, Leo, Rivera, Yessenia M., Drane, Quentin H., Corcos, Daniel M., David, Fabian J., Goelz, Lisa C.

“…•Saccade latency is prolonged as disease severity increases, irrespective of whether participants were off or on medication.•Medication effects interact with…”
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Subthalamic Physiology in Genetic Subtypes of Parkinson's Disease by Pal, Gian D., David, Fabian J., Shils, Jay L., Munoz, Miranda J., Afshari, Mitra, Sani, Sepehr, Verhagen Metman, Leo, Corcos, Daniel M.

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Medication only improves limb movements while deep brain stimulation improves eye and limb movements during visually-guided reaching in Parkinson's disease by Munoz, Miranda J, Arora, Rishabh, Rivera, Yessenia M, Drane, Quentin H, Pal, Gian D, Verhagen Metman, Leo, Sani, Sepehr B, Rosenow, Joshua M, Goelz, Lisa C, Corcos, Daniel M, David, Fabian J

“…Antiparkinson medication and subthalamic nucleus deep brain stimulation (STN-DBS), two common treatments of Parkinson's disease (PD), effectively improve…”
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Abnormal lipopolysaccharide binding protein as marker of gastrointestinal inflammation in Parkinson disease by Pal, Gian D, Shaikh, Maliha, Forsyth, Christopher B, Ouyang, Bichun, Keshavarzian, Ali, Shannon, Kathleen M

“…An inflammation-driven model of PD has been proposed based on the endotoxin lipopolysaccaride (LPS), a potential source of inflammation in the gastrointestinal…”
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Gait asymmetry in glucocerebrosidase mutation carriers with Parkinson's disease by Gera, Anjali, O'Keefe, Joan A, Ouyang, Bichun, Liu, Yuanqing, Ruehl, Samantha, Buder, Mark, Joyce, Jessica, Purcell, Nicolette, Pal, Gian

“…GBA mutation carriers with PD (PD-GBA) are at higher risk of cognitive decline, but there is limited data regarding whether there are differences in gait…”
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Comparison of neuropathology in Parkinson's disease subjects with and without deep brain stimulation by Pal, Gian D., Ouyang, Bichun, Serrano, Geidy, Shill, Holly A., Goetz, Christopher, Stebbins, Glenn, Metman, Leo Verhagen, Driver‐Dunckley, Erika, Mehta, Shyamal H., Caviness, John N., Sabbagh, Marwan N., Adler, Charles H., Beach, Thomas G.

“…ABSTRACT Background: The aim of this postmortem study was to compare, in Parkinson's disease subjects with and without bilateral subthalamic nucleus deep brain…”
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Deep nasal sinus cavity microbiota dysbiosis in Parkinson’s disease by Pal, Gian, Ramirez, Vivian, Engen, Phillip A., Naqib, Ankur, Forsyth, Christopher B., Green, Stefan J., Mahdavinia, Mahboobeh, Batra, Pete S., Tajudeen, Bobby A., Keshavarzian, Ali

“…Olfactory dysfunction is a pre-motor symptom of Parkinson’s disease (PD) that appears years prior to diagnosis and can affect quality of life in PD. Changes in…”
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Medication improves velocity, reaction time, and movement time but not amplitude or error during memory‐guided reaching in Parkinson's disease by Trevarrow, Michael P., Munoz, Miranda J., Rivera, Yessenia M., Arora, Rishabh, Drane, Quentin H., Pal, Gian D., Verhagen Metman, Leonard, Goelz, Lisa C., Corcos, Daniel M., David, Fabian J.

“…The motor impairments experienced by people with Parkinson's disease (PD) are exacerbated during memory‐guided movements. Despite this, the effect of…”
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Encoding type, medication, and deep brain stimulation differentially affect memory-guided sequential reaching movements in Parkinson's disease by David, Fabian J, Rivera, Yessenia M, Entezar, Tara K, Arora, Rishabh, Drane, Quentin H, Munoz, Miranda J, Rosenow, Joshua M, Sani, Sepehr B, Pal, Gian D, Verhagen-Metman, Leonard, Corcos, Daniel M

“…Memory-guided movements, vital to daily activities, are especially impaired in Parkinson's disease (PD). However, studies examining the effects of how…”
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Subthalamic Peak Beta Ratio Is Asymmetric in Glucocerebrosidase Mutation Carriers With Parkinson's Disease: A Pilot Study by David, Fabian J, Munoz, Miranda J, Shils, Jay L, Pauciulo, Michael W, Hale, Philip T, Nichols, William C, Afshari, Mitra, Sani, Sepehr, Verhagen Metman, Leo, Corcos, Daniel M, Pal, Gian D

“…Up to 27% of individuals undergoing subthalamic nucleus deep brain stimulation (STN-DBS) have a genetic form of Parkinson's disease (PD). G ( ) mutation…”
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Digital gait markers to potentially distinguish fragile X-associated tremor/ataxia syndrome, Parkinson's disease, and essential tremor by Robertson-Dick, Erin E, Timm, Emily C, Pal, Gian, Ouyang, Bichun, Liu, Yuanqing, Berry-Kravis, Elizabeth, Hall, Deborah A, O'Keefe, Joan A

“…Fragile X-associated tremor/ataxia syndrome (FXTAS), a neurodegenerative disease that affects carriers of a 55-200 CGG repeat expansion in the ( ) gene, may be…”
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The effect of subthalamic nucleus deep brain stimulation volume of tissue activated on visually-guided reaching by Munoz, Miranda, Rivera, Yessenia, Drane, Quentin, Arora, Rishabh, Entezar, Tara, Pal, Gian, Metman, Leo Verhagen, Sani, Sepehr, Rosenow, Joshua, Kurani, Ajay

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The Effects of Subthalamic Nucleus Deep Brain Stimulation and Retention Delay on Memory-Guided Reaching Performance in People with Parkinson’s Disease by Trevarrow, Michael P., Munoz, Miranda J., Rivera, Yessenia M., Arora, Rishabh, Drane, Quentin H., Rosenow, Joshua M., Sani, Sepehr B., Pal, Gian D., Verhagen Metman, Leonard, Goelz, Lisa C., Corcos, Daniel M., David, Fabian J.

“…Background: Subthalamic nucleus deep brain stimulation (STN-DBS) improves intensive aspects of movement (velocity) in people with Parkinson’s disease (PD) but…”
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NIH Toolbox performance of persons with Parkinson's disease according to GBA1 and STN‐DBS status by Almelegy, Ahmad, Gunda, Srujanesh, Buyske, Steven, Rosenbaum, Marc, Sani, Sepehr, Afshari, Mitra, Metman, Leo V., Goetz, Christopher G., Hall, Deborah, Mouradian, M. Maral, Pal, Gian

“…Objective Mutations in the glucocerebrosidase (GBA1) gene and subthalamic nucleus deep brain stimulation (STN‐DBS) are independently associated with cognitive…”
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Neither alpha-synuclein fibril strain nor host murine genotype influences seeding efficacy by Walton, Sara, Fenyi, Alexis, Tittle, Tyler, Sidransky, Ellen, Pal, Gian, Choi, Solji, Melki, Ronald, Killinger, Bryan A., Kordower, Jeffrey H.

“…Parkinson’s disease (PD) is a neurodegenerative disease characterized by progressive motor symptoms and alpha-synuclein (αsyn) aggregation in the nervous…”
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