Search Results - "Pakravan, Katayoon"
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Cancer-associated fibroblasts drive colorectal cancer cell progression through exosomal miR-20a-5p-mediated targeting of PTEN and stimulating interleukin-6 production
Published in BMC cancer (01-04-2024)“…This study evaluated the clinical relevance of a set of five serum-derived circulating microRNAs (miRNAs) in colorectal cancer (CRC). Additionally, we…”
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Monocytes educated by cancer-associated fibroblasts secrete exosomal miR-181a to activate AKT signaling in breast cancer cells
Published in Journal of translational medicine (03-12-2022)“…Cancer-associated fibroblasts (CAFs), one of the major components of the tumor stroma, contribute to an immunosuppressive tumor microenvironment (TME) through…”
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Docosahexaenoic acid reverses the promoting effects of breast tumor cell-derived exosomes on endothelial cell migration and angiogenesis
Published in Life sciences (1973) (01-01-2021)“…As a natural compound, docosahexaenoic acid (DHA) exerts anti-cancer and anti-angiogenesis functions through exosomes; however, little is known about the…”
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4
Exosomal circ_0084043 derived from colorectal cancer-associated fibroblasts promotes in vitro endothelial cell angiogenesis by regulating the miR-140–3p/HIF-1α/VEGF signaling axis
Published in Heliyon (15-06-2024)“…Circular RNAs (circRNAs) hold potential as diagnostic markers for colorectal cancer (CRC); however, their functional mechanisms remain incompletely elucidated…”
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A panel of six-circulating miRNA signature in serum and its potential diagnostic value in colorectal cancer
Published in Life sciences (1973) (01-10-2020)“…Colorectal carcinoma (CRC) is one of the most prevalent cancers throughout the world. Circulating serum-derived microRNAs (miRNAs, miRs) can be used as…”
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MicroRNA-100 shuttled by mesenchymal stem cell-derived exosomes suppresses in vitro angiogenesis through modulating the mTOR/HIF-1α/VEGF signaling axis in breast cancer cells
Published in Cellular oncology (Dordrecht) (01-10-2017)“…Background Human mesenchymal stem cells (MSCs) have been shown to be involved in the formation and modulation of tumor stroma and in interacting with tumor…”
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TET1 regulates stem cell properties and cell cycle of Cancer stem cells in triple-negative breast cancer via DNA demethylation
Published in Biochemical pharmacology (01-01-2024)“…The role of cancer stem cells in metastasis, recurrence, and resistance to conventional therapies is significant. Addressing these cells could potentially…”
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Colorectal cancer-secreted exosomal circ_001422 plays a role in regulating KDR expression and activating mTOR signaling in endothelial cells by targeting miR-195-5p
Published in Journal of cancer research and clinical oncology (01-10-2023)“…Background As non-coding RNAs, exosomal circular RNAs (circRNAs) regulate colorectal cancer (CRC) progression, although the functional mechanisms by which such…”
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9
Colorectal cancer cell-derived extracellular vesicles transfer miR-221-3p to promote endothelial cell angiogenesis via targeting suppressor of cytokine signaling 3
Published in Life sciences (1973) (15-11-2021)“…Secreted microRNAs (miRNAs) can serve as promising diagnostic markers for colorectal cancer (CRC). Herein, we evaluated the potential clinical significance of…”
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Exosomes released by oxidative stress-induced mesenchymal stem cells promote murine mammary tumor progression through activating the STAT3 signaling pathway
Published in Molecular and cellular biochemistry (01-12-2024)“…Mesenchymal stem cells (MSCs) may play a pivotal role in shaping the tumor microenvironment (TME), influencing tumor growth. Nonetheless, conflicting evidence…”
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SMAD4 contributes to chondrocyte and osteocyte development
Published in Journal of cellular and molecular medicine (01-01-2022)“…Different cellular and molecular mechanisms contribute to chondrocyte and osteocyte development. Although vital roles of the mothers against decapentaplegic…”
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12
Prostate cancer stem cells: from theory to practice
Published in Scandinavian journal of urology (01-04-2017)“…None of the generally accepted theories on prostate cancer development can fully explain many distinguishing features of the disease, such as intratumoral…”
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Upregulation of the long noncoding RNAs DSCAM‐AS1 and MANCR is a potential diagnostic marker for breast carcinoma
Published in Biotechnology and applied biochemistry (01-12-2021)“…Breast cancer (BC) is one of the most common malignancies among women in the world. There is a global attempt to diagnose BC as early as possible. Long…”
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Novel strategies for targeting leukemia stem cells: sounding the death knell for blood cancer
Published in Cellular oncology (Dordrecht) (01-02-2017)“…Background Cancer stem cells (CSCs), also known as tumor-initiating cells (TICs), are characterized by high self-renewal and multi-lineage differentiation…”
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