Search Results - "Pakker, Nadine"

Hepatitis B and C virus co-infection and the risk for hepatotoxicity of highly active antiretroviral therapy in HIV-1 infection by BRINKER, Marieke Den, WIT, Ferdinand W. N. M, LANGE, Joep M. A, WERTHEIM-VAN DILLEN, Pauline M. E, JURRIAANS, Suzanne, WEEL, Jan, VAN LEEUWEN, Remko, PAKKER, Nadine G, REISS, Peter, DANNER, Sven A, WEVERLING, Gerrit Jan

“…To investigate the risk of hepatotoxicity after initiation of protease inhibitor-containing highly active antiretroviral therapy (HAART) for HIV-1 infected…”
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Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: A composite of redistribution and proliferation by Pakker, Nadine G, Notermans, Daan W, De Boer, Rob J, Roos, Marijke T.L, Wolf, Frank De, Hill, Andrew, Leonard, John M, Danner, Sven A, Miedema, Frank, Schellekens, Peter T.A

“…The origin of CD4+ T cells reappearing in the blood following antiretroviral therapy in human immunodeficiency virus type-1 (HIV-1) infection is still…”
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Pharmacokinetics and pharmacodynamics of intravenous artesunate during severe malaria treatment in Ugandan adults by Byakika-Kibwika, Pauline, Lamorde, Mohammed, Mayito, Jonathan, Nabukeera, Lillian, Mayanja-Kizza, Harriet, Katabira, Elly, Hanpithakpong, Warunee, Obua, Celestino, Pakker, Nadine, Lindegardh, Niklas, Tarning, Joel, de Vries, Peter J, Merry, Concepta

“…Severe malaria is a medical emergency with high mortality. Prompt achievement of therapeutic concentrations of highly effective anti-malarial drugs reduces the…”
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Immune Reconstitution after 2 Years of Successful Potent Antiretroviral Therapy in Previously Untreated Human Immunodeficiency Virus Type 1-Infected Adults by Notermans, Daan W., Pakker, Nadine G., Hamann, Dörte, Foudraine, Norbert A., Kauffmann, Robert H., Meenhorst, Pieter L., Goudsmit, Jaap, Roos, Marijke T. L., Schellekens, Peter T. A., Miedema, Frank, Danner, Sven A.

“…Today's antiretroviral combination regimens can induce significant and sustained decreases in human immunodeficiency virus (HIV)-RNA levels, allowing the…”
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Temporal Relationship between Human Immunodeficiency Virus Type 1 RNA Levels in Serum and Cellular Infectious Load in Peripheral Blood by Blaak, Hetty, Wolf, Frank de, van 't Wout, Angelique B., Pakker, Nadine G., Bakker, Margreet, Goudsmit, Jaap, Schuitemaker, Hanneke

“…Cross-sectional analysis of 252 paired serum and peripheral blood mononuclear cell (PBMC) samples derived from 54 human immunodeficiency virus type 1…”
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Lack of elevated pre-ART elastase-ANCA levels in patients developing TB-IRIS by Goovaerts, Odin, Massinga-Loembé, Marguerite, Ondoa, Pascale, Ceulemans, Ann, Worodria, William, Mayanja-Kizza, Harriet, Colebunders, Robert, Kestens, Luc

“…Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) in HIV-TB co-infected patients receiving antiretroviral therapy (ART) has been…”
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Significant pharmacokinetic interactions between artemether/lumefantrine and efavirenz or nevirapine in HIV-infected Ugandan adults by Byakika-Kibwika, Pauline, Lamorde, Mohammed, Mayito, Jonathan, Nabukeera, Lillian, Namakula, Rhoda, Mayanja-Kizza, Harriet, Katabira, Elly, Ntale, Muhammad, Pakker, Nadine, Ryan, Mairin, Hanpithakpong, Warunee, Tarning, Joel, Lindegardh, Niklas, de Vries, Peter J, Khoo, Saye, Back, David, Merry, Concepta

“…Co-administration of artemether/lumefantrine with antiretroviral therapy has potential for pharmacokinetic drug interactions. We investigated drug-drug…”
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Increased KLRG1 and PD-1 expression on CD8 T lymphocytes in TB-IRIS by Goovaerts, Odin, Massinga-Loembé, Marguerite, Ondoa, Pascale, Ceulemans, Ann, Worodria, William, Mayanja-Kizza, Harriet, Colebunders, Robert, Kestens, Luc

“…Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) is an inflammatory complication in HIV-TB co-infected patients receiving…”
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Prevention of Early Mortality by Presumptive Tuberculosis Therapy Study: An Open Label, Randomized Controlled Trial by Manabe, Yukari C, Worodria, William, van Leth, Frank, Mayanja-Kizza, Harriet, Traore, Afsatou Ndama, Ferro, Josefo, Pakker, Nadine, Frank, Matthias, Grobusch, Martin P, Colebunders, Robert, Cobelens, Frank

“…Early mortality after initiation of antiretroviral therapy (ART) occurs in 9-39% of patients in sub-Saharan Africa. A significant proportion of deaths are…”
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Clinically relevant thresholds for ultrasensitive HIV drug resistance testing: a multi-country nested case-control study by Inzaule, Seth C, Hamers, Raph L, Noguera-Julian, Marc, Casadellà, Maria, Parera, Mariona, Kityo, Cissy, Steegen, Kim, Naniche, Denise, Clotet, Bonaventura, Rinke de Wit, Tobias F, Paredes, Roger, Osibogun, Akin, Wallis, Carole L., Nalubwama, Cathy, Letsoalo, Esrom, Senono, Fred, Adelabu, Hameed, Kakooza, Hanipha, Namata, Harriet, Sanne, Ian, Nankya, Immaculate, Menke, Jack, Lange, Joep M.A., Sigaloff, Kim C.E., Mandaliya, Kishor, Hardman, Margaret, Siwale, Margaret, de Jager, Marleen, Dolan, Marian, Botes, Mariette E., O'Mello, Martin, Wellington, Maureen, Mutebi, Miiro, Nakitto, Miriam, Labib, Moheb, Pakker, Nadine, Ondoa, Pascale, Mugyenyi, Peter, Ive, Prudence, Nakanjako, Ritah, Schuurman, Rob, Lüthy, Ruedi, Balinda, Sheila N., Akanmu, Sulaimon, Boender, T. Sonia, Adeyemo, Titilope A., Rodoye, Tope, Stevens, Wendy S., Namala, Winnie

“…Implementation of ultrasensitive HIV drug resistance tests for routine clinical use is hampered by uncertainty about the clinical relevance of drug-resistant…”
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Integration of antenatal syphilis screening in an urban HIV clinic: a feasibility study by Manabe, Yukari C, Namale, Gertrude, Nalintya, Elizabeth, Sempa, Joseph, Ratanshi, Rosalind Parkes, Pakker, Nadine, Katabira, Elly

“…Syphilis infection during pregnancy leads to avoidable morbidity and mortality and remains a significant problem in sub-Saharan Africa. Despite global…”
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LPS-binding protein and IL-6 mark paradoxical tuberculosis immune reconstitution inflammatory syndrome in HIV patients by Goovaerts, Odin, Jennes, Wim, Massinga-Loembé, Marguerite, Ceulemans, Ann, Worodria, William, Mayanja-Kizza, Harriet, Colebunders, Robert, Kestens, Luc

“…Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) remains a poorly understood complication in HIV-TB co-infected patients…”
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Kinetics of immune functions and virus replication during HIV-1 infection by Pontesilli, Oscar, Klein, Michèl R, Kerkhof-Garde, Susana R, Pakker, Nadine G, de Wolf, Frank, Schuitemaker, Hanneke, Miedema, Frank

“…Introduction: Kinetics of human immunodeficiency virus type 1 (HIV-1) cytotoxic T lymphocyte (CTL) responses and viral load were evaluated in HIV-1 infected…”
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Lopinavir/ritonavir significantly influences pharmacokinetic exposure of artemether/lumefantrine in HIV-infected Ugandan adults by BYAKIKA-KIBWIKA, Pauline, LAMORDE, Mohammed, DE VRIES, Peter J, BACK, David, KHOO, Saye, MERRY, Concepta, OKABA-KAYOM, Violet, MAYANJA-KIZZA, Harriet, KATABIRA, Elly, HANPITHAKPONG, Warunee, PAKKER, Nadine, DORLO, Thomas P. C, TARNING, Joel, LINDEGARDH, Niklas

“…Treatment of HIV/malaria-coinfected patients with antiretroviral therapy (ART) and artemisinin-based combination therapy has potential for drug interactions…”
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Effect of changing antiretroviral treatment eligibility criteria on patient load in Kampala, Uganda by Konde-Lule, Joseph, Makumbi, Fred, Pakker, Nadine, Muyinda, Asad, Mubiru, Mesach, Cobelens, Frank G.J.

“…In many resource-poor countries, CD4 count thresholds of eligibility for antiretroviral treatment (ART) were initially low (<200 cells/mm 3 ) but are now being…”
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SAFETY AND IMMUNOGENICITY OF CO-ADMINISTERED HOOKWORM VACCINE CANDIDATES NA-GST-1 AND NA-APR-1 WITH ALHYDROGEL® AND GLUCOPYRANOSYL-LIPID A IN GABONESE ADULTS: INTERIM RESULTS by Adegnika, Ayola, Vries, Sophie De, Zinsou, Frejus Jeannot, Honkpehedji, J, Dejon, Jean Claude, Loembe, Marguerite Massinga, Bache, Bache, Pakker, Nadine, Leeuwen, Remko Van, Hounkpatin, Aurore Bouyoukou, Kremsner, Peter, Yazdanbakhsh, Maria, Lell, Bertrand, Bethony, Jeffrey, Hotez, Peter, Diemert, David, Grobusch, Martin

“…BackgroundHookworm disease is one of the most prevalent of the neglected tropical diseases. To date, the control of hookworm infection has been limited to…”
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Evidence That both HIV and HIV-Induced Immunodeficiency Enhance HCV Replication among HCV Seroconverters by Beld, Marcel, Penning, Maarten, Lukashov, Vladimir, McMorrow, Martin, Roos, Marijke, Pakker, Nadine, van den Hoek, Anneke, Goudsmit, Jaap

“…The objective of this retrospective cohort study is to assess the mechanism by which human immunodeficiency virus type 1 (HIV) influences hepatitis C virus…”
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Longitudinal Analysis of Human Immunodeficiency Virus Type 1—Specific Cytotoxic T Lymphocyte Responses: A Predominant Gag-Specific Response Is Associated with Nonprogressive Infection by Pontesilli, Oscar, Klein, Michèl R., Kerkhof-Garde, Susana R., Pakker, Nadine G., de Wolf, Frank, Schuitemaker, Hanneke, Miedema, Frank

“…To establish correlates of protective immunity during human immunodeficiency virus type 1 (HIV-1) infection, the frequencies of circulating cytotoxic T…”
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Effects of Nevirapine, Compared with Lamivudine, on Lipids and Lipoproteins in HIV-1—Uninfected Newborns: The Stopping Infection from Mother-to-Child via Breast-Feeding in Africa Lipid Substudy by Sankatsing, Raaj R., Wit, Ferdinand W., Pakker, Nadine, Vyankandondera, Joseph, Mmiro, Francis, Okong, Pius, Kastelein, John J., Lange, Joep M., Stroes, Erik S., Reiss, Peter

“…Background. The objective of the present study was to assess whether the high-density lipoprotein cholesterol (HDL-c)-increasing effect of nevirapine (NVP), as…”
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Immune restoration does not invariably occur following long-term HIV-1 suppression during antiretroviral therapy by PAKKER, N. G, KROON, E. D. M. B, KOOPMANS, P. P, KROON, F. P, TEN NAPEL, C. H. H, SPRENGER, H. G, WEIGEL, H. M, MONTANER, J. S. G, LANGE, J. M. A, REISS, P, SCHELLEKENS, P. T. A, MIEDEMA, F, ROOS, M. T. L, OTTO, S. A, HALLS, D, WIT, F. W. N. M, HAMANN, D, VAN DER ENDE, M. E, CLAESSEN, F. A. P, KAUFFMANN, R. H

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