Search Results - "Pakkenberg, B."

Neocortical glial cell numbers in human brains by Pelvig, D.P, Pakkenberg, H, Stark, A.K, Pakkenberg, B

“…Abstract Stereological cell counting was applied to post-mortem neocortices of human brains from 31 normal individuals, age 18–93 years, 18 females (average…”
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Neuronal loss, demyelination and volume change in the multiple sclerosis neocortex by Carassiti, D., Altmann, D. R., Petrova, N., Pakkenberg, B., Scaravilli, F., Schmierer, K.

“…Aims Indices of brain volume [grey matter, white matter (WM), lesions] are being used as outcomes in clinical trials of patients with multiple sclerosis (MS)…”
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A stereological study of the mediodorsal thalamic nucleus in Down syndrome by Karlsen, A.S, Korbo, S, Uylings, H.B.M, Pakkenberg, B

“…Highlights • The mediodorsal thalamus was investigated in aged patients with Down syndrome (DS). • Compared to controls, the DS brains had 40% fewer neurons. •…”
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Hidradenitis suppurativa: a disease of the absent sebaceous gland? Sebaceous gland number and volume are significantly reduced in uninvolved hair follicles from patients with hidradenitis suppurativa by Kamp, S., Fiehn, A.M., Stenderup, K., Rosada, C., Pakkenberg, B., Kemp, K., Dam, T.N., Jemec, G.B.

“…Summary Background  The pathogenesis of hidradenitis suppurativa (HS) is not clearly understood. The nomenclature suggests an important role for the apocrine…”
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A neural cell adhesion molecule–derived peptide reduces neuropathological signs and cognitive impairment induced by Aβ25-35 by Klementiev, B, Novikova, T, Novitskaya, V, Walmod, P.S, Dmytriyeva, O, Pakkenberg, B, Berezin, V, Bock, E

“…Abstract By means of i.c.v. administration of preaggregated oligomeric β-amyloid (Aβ)25-35 peptide it was possible in rats to generate neuropathological signs…”
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Growth factor and proteinase profile of Vivostat® platelet-rich fibrin linked to tissue repair by Ågren, M. S., Rasmussen, K., Pakkenberg, B., Jørgensen, B.

“…Background and Objectives Autologous platelet‐rich fibrin (PRF®) is prepared by the automatic Vivostat® system. Conflicting results with Vivostat PRF in acute…”
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Histological changes of the dopaminergic nigrostriatal system in aging by Stark, A K, Pakkenberg, B

“…Although the maximum human lifespan has not increased in recent history, average life expectancy has risen dramatically since the beginning of the last…”
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Total nerve cell number in neocortex in chronic schizophrenics and controls estimated using optical disectors by Pakkenberg, B

“…The total number of neurons was estimated in eight brains from chronic schizophrenic men and compared with 16 gender- and age-matched controls. The average…”
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The temporal pattern of postnatal neurogenesis found in the neocortex of the Göttingen minipig brain by Hou, J, Eriksen, N, Pakkenberg, B

“…Abstract The Göttingen minipig (G-mini) is increasingly used as a non-primate model for human neurological diseases. We applied design-based stereology on five…”
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Schizophrenia; from structure to function with special focus on the mediodorsal thalamic prefrontal loop by Pakkenberg, B., Scheel-Krüger, J., Kristiansen, L. V.

“…Objective:  To describe structural and biochemical evidence from postmortem brains that implicates the reciprocal connections between the mediodorsal thalamic…”
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Unaltered neuronal and glial counts in animal models of magnetic seizure therapy and electroconvulsive therapy by Dwork, A.J, Christensen, J.R, Larsen, K.B, Scalia, J, Underwood, M.D, Arango, V, Pakkenberg, B, Lisanby, S.H

“…Abstract Anatomical evidence of brain damage from electroconvulsive therapy (ECT) is lacking; but there are no modern stereological studies in primates…”
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Age-Induced White Matter Changes in the Human Brain: A Stereological Investigation by Tang, Y, Nyengaard, J.R, Pakkenberg, B, Gundersen, H.J.G

“…In the present pilot study, age-related white matter changes were investigated by the use of design-based stereological methods. In the brains of elderly…”
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The volume of the mediodorsal thalamic nucleus in treated and untreated schizophrenics by Pakkenberg, B

“…Reductions of 40% in total cell number and 25% in volume of the mediodorsal thalamic nucleus were recently reported in an unbiased neurostereological study of…”
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Hippocampal neuron and glial cell numbers in Parkinson's disease-A stereological study by Joelving, F.C., Billeskov, R., Christensen, J.R., West, M., Pakkenberg, B.

“…Hippocampal atrophy and neuron loss are early and reproducible findings in Alzheimer's disease, and recent magnetic resonance imaging studies indicate that…”
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The effect of age and gender on the volume and size distribution of neocortical neurons by Stark, A.K, Toft, M.H, Pakkenberg, H, Fabricius, K, Eriksen, N, Pelvig, D.P, Møller, M, Pakkenberg, B

“…Abstract Since the turn of the last century, the average life expectancy has risen considerably. Lengthening of life span has little merit if the quality of…”
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The postnatal growth of the beta-cell mass in pigs by Bock, T, Kyhnel, A, Pakkenberg, B, Buschard, K

“…Studies of the postnatal growth of the beta-cell mass in rats have revealed some unexpected and apparently paradoxical results, the most prominent being a…”
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Ageing of substantia nigra in humans: cell loss may be compensated by hypertrophy by Cabello, C. R., Thune, J. J., Pakkenberg, H., Pakkenberg, B.

“…In a stereological study of the human substantia nigra (SN), the total number of melanin‐positive and melanin‐negative neurones from 28 male subjects aged…”
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No changes in neocortical cell volumes or glial cell numbers in chronic alcoholic subjects compared to control subjects by Fabricius, Katrine, Pakkenberg, Henning, Pakkenberg, Bente

“…Aims: To study if the total glial cell population in the neocortex is intact in subjects with a history of severe alcohol abuse compared to control subjects…”
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The saucor, a new stereological tool for analysing the spatial distributions of cells, exemplified by human neocortical neurons and glial cells by STARK, A.K., GUNDERSEN, H.J.G., GARDI, J.E., PAKKENBERG, B., HAHN, U.

“…Summary The 3D spatial arrangement of particles or cells, for example glial cells, with respect to other particles or cells, for example neurons, can be…”
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No change in total length of white matter fibers in Alzheimer's disease by Jørgensen, A.-M.B, Marner, L, Pakkenberg, B

“…Abstract White matter changes have been reported as part of Alzheimer dementia. To investigate this, the total subcortical myelinated nerve fiber length was…”
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