Search Results - "Paki, Katharina"
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The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant
Published in Nature communications (04-12-2019)“…Pandemic influenza A virus (IAV) outbreaks occur when strains from animal reservoirs acquire the ability to infect and spread among humans. The molecular basis…”
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The RNA Helicase DDX6 Associates with RIG-I to Augment Induction of Antiviral Signaling
Published in International journal of molecular sciences (26-06-2018)“…Virus infections induce sensitive antiviral responses within the host cell. The RNA helicase retinoic acid-inducible gene I (RIG-I) is a key sensor of…”
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Quantitative Proteomic Approach Identifies Vpr Binding Protein as Novel Host Factor Supporting Influenza A Virus Infections in Human Cells
Published in Molecular & cellular proteomics (01-05-2017)“…Influenza A virus (IAV) infections are a major cause for respiratory disease in humans, which affects all age groups and contributes substantially to global…”
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Disruption of Src homology 3-binding motif within non-structural protein 1 of influenza B virus unexpectedly enhances viral replication in human cells
Published in Journal of general virology (01-11-2016)“…The influenza virus non-structural protein 1 (NS1) is a multifunctional virulence factor that plays a crucial role during infection by blocking the innate…”
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Annexin V incorporated into influenza virus particles inhibits gamma interferon signaling and promotes viral replication
Published in Journal of virology (01-10-2014)“…During the budding process, influenza A viruses (IAVs) incorporate multiple host cell membrane proteins. However, for most of them, their significance in viral…”
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