Search Results - "Pakharukova, Natalia"

Structural Insight into Archaic and Alternative Chaperone-Usher Pathways Reveals a Novel Mechanism of Pilus Biogenesis by Pakharukova, Natalia, Garnett, James A, Tuittila, Minna, Paavilainen, Sari, Diallo, Mamou, Xu, Yingqi, Matthews, Steve J, Zavialov, Anton V

“…Gram-negative pathogens express fibrous adhesive organelles that mediate targeting to sites of infection. The major class of these organelles is assembled via…”
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Methylation, crystallization and SAD phasing of the Csu pilus CsuC–CsuE chaperone–adhesin subunit pre‐assembly complex from Acinetobacter baumannii by Pakharukova, Natalia, Tuittila, Minna, Paavilainen, Sari, Zavialov, Anton

“…Acinetobacter baumannii is one of the most difficult Gram‐negative bacteria to control and treat. This pathogen forms biofilms on hospital surfaces and medical…”
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Structural insight into host recognition by aggregative adherence fimbriae of enteroaggregative Escherichia coli by Berry, Andrea A, Yang, Yi, Pakharukova, Natalia, Garnett, James A, Lee, Wei-chao, Cota, Ernesto, Marchant, Jan, Roy, Saumendra, Tuittila, Minna, Liu, Bing, Inman, Keith G, Ruiz-Perez, Fernando, Mandomando, Inacio, Nataro, James P, Zavialov, Anton V, Matthews, Steve

“…Enteroaggregative Escherichia coli (EAEC) is a leading cause of acute and persistent diarrhea worldwide. A recently emerged Shiga-toxin-producing strain of…”
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Structural basis for Acinetobacter baumannii biofilm formation by Pakharukova, Natalia, Tuittila, Minna, Paavilainen, Sari, Malmi, Henri, Parilova, Olena, Teneberg, Susann, Knight, Stefan D., Zavialov, Anton V.

“…Acinetobacter baumannii—a leading cause of nosocomial infections—has a remarkable capacity to persist in hospital environments and medical devices due to its…”
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Allosteric activation of proto-oncogene kinase Src by GPCR–beta-arrestin complexes by Pakharukova, Natalia, Masoudi, Ali, Pani, Biswaranjan, Staus, Dean P., Lefkowitz, Robert J.

“…G protein–coupled receptors (GPCRs) initiate signaling cascades via G-proteins and beta-arrestins (βarr). βarr-dependent actions begin with recruitment of βarr…”
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The GPCR–β-arrestin complex allosterically activates C-Raf by binding its amino terminus by Zang, Yunxiang, Kahsai, Alem W., Pakharukova, Natalia, Huang, Li-yin, Lefkowitz, Robert J.

“…G protein–coupled receptors (GPCRs) convert external stimuli into cellular signals through heterotrimeric guanine nucleotide-binding proteins (G-proteins) and…”
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Archaic chaperone–usher pili self-secrete into superelastic zigzag springs by Pakharukova, Natalia, Malmi, Henri, Tuittila, Minna, Dahlberg, Tobias, Ghosal, Debnath, Chang, Yi-Wei, Myint, Si Lhyam, Paavilainen, Sari, Knight, Stefan David, Lamminmäki, Urpo, Uhlin, Bernt Eric, Andersson, Magnus, Jensen, Grant, Zavialov, Anton V.

“…Adhesive pili assembled through the chaperone–usher pathway are hair-like appendages that mediate host tissue colonization and biofilm formation of…”
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Archaic and alternative chaperones preserve pilin folding energy by providing incomplete structural information by Pakharukova, Natalia, McKenna, Sophie, Tuittila, Minna, Paavilainen, Sari, Malmi, Henri, Xu, Yingqi, Parilova, Olena, Matthews, Steve, Zavialov, Anton V.

“…Adhesive pili are external component of fibrous adhesive organelles and help bacteria attach to biotic or abiotic surfaces. The biogenesis of adhesive pili via…”
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Allosteric activation of proto-oncogene kinase Src by GPCR-beta-arrestin complexes by Pakharukova, Natalia, Masoudi, Ali, Pani, Biswaranjan, Staus, Dean P, Lefkowitz, Robert J

“…G protein-coupled receptors (GPCRs) initiate signaling cascades via G-proteins and beta-arrestins (βarr). βarr-dependent actions begin with recruitment of βarr…”
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Structural basis for Myf and Psa fimbriae‐mediated tropism of pathogenic strains of Yersinia for host tissues by Pakharukova, Natalia, Roy, Saumendra, Tuittila, Minna, Rahman, Mohammad M., Paavilainen, Sari, Ingars, Anna‐Karin, Skaldin, Maksym, Lamminmäki, Urpo, Härd, Torleif, Teneberg, Susann, Zavialov, Anton V.

“…Summary Three pathogenic species of the genus Yersinia assemble adhesive fimbriae via the FGL‐chaperone/usher pathway. Closely related Y. pestis and Y…”
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Crystallization and preliminary X-ray diffraction analysis of the Csu pili CsuC-CsuA/B chaperone-major subunit pre-assembly complex from Acinetobacter baumannii by Pakharukova, Natalia, Tuittila, Minna, Paavilainen, Sari, Zavialov, Anton

“…The attachment of many Gram‐negative pathogens to biotic and abiotic surfaces is mediated by fimbrial adhesins, which are assembled via the classical,…”
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Structural Insight into Archaic and Alternative Chaperone-Usher Pathways Reveals a Novel Mechanism of Pilus Biogenesis: e1005269 by Pakharukova, Natalia, Garnett, James A, Tuittila, Minna, Paavilainen, Sari, Diallo, Mamou, Xu, Yingqi, Matthews, Steve J, Zavialov, Anton V

“…Gram-negative pathogens express fibrous adhesive organelles that mediate targeting to sites of infection. The major class of these organelles is assembled via…”
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Crystallization and sulfur SAD phasing of AggA, the major subunit of aggregative adherence fimbriae type I from the Escherichia coli strain that caused an outbreak of haemolytic-uraemic syndrome in Germany by Pakharukova, Natalia, Tuittila, Minna, Zavialov, Anton

“…The outbreak of Shiga toxin‐producing Escherichia coli O104:H4 infection in Germany in 2011 was associated with significant mortality and morbidity owing to…”
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Structural Insight into Host Recognition by Aggregative Adherence Fimbriae of Enteroaggregative Escherichia coli: e1004404 by Berry, Andrea A, Yang, Yi, Pakharukova, Natalia, Garnett, James A, Lee, Wei-chao, Cota, Ernesto, Marchant, Jan, Roy, Saumendra, Tuittila, Minna, Liu, Bing, Inman, Keith G, Ruiz-Perez, Fernando, Mandomando, Inacio, Nataro, James P, Zavialov, Anton V, Matthews, Steve

“…Enteroaggregative Escherichia coli (EAEC) is a leading cause of acute and persistent diarrhea worldwide. A recently emerged Shiga-toxin-producing strain of…”
Get full text