Search Results - "Pakarinen, P."
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ERNICA guidelines for the management of rectosigmoid Hirschsprung's disease
Published in Orphanet journal of rare diseases (25-06-2020)“…Hirschsprung's disease (HSCR) is a serious congenital bowel disorder with a prevalence of 1/5000. Currently, there is a lack of systematically developed…”
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Bacterial translocation markers and toll‐like receptors in biliary atresia following successful portoenterostomy
Published in Acta Paediatrica (01-10-2023)“…Aim The gut–liver axis may contribute to pathophysiology of cholestatic liver disorders like biliary atresia (BA) by bacterial translocation (BT). Toll‐like…”
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Long-term outcomes and quality of life in patients with Hirschsprung disease
Published in World Journal of Pediatric Surgery (09-10-2024)“…Although patients with Hirschsprung disease are mostly affected by imperfect bowel function and fecal control in the long term, they are also predisposed to…”
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Persistent abnormal liver fibrosis after weaning off parenteral nutrition in pediatric intestinal failure
Published in Hepatology (Baltimore, Md.) (01-08-2013)“…The aim of this study was to evaluate the long‐term effects of pediatric intestinal failure (IF) on liver histology. Altogether, 38 IF patients (median age:…”
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Intestinal Commitment and Maturation of Human Pluripotent Stem Cells Is Independent of Exogenous FGF4 and R-spondin1
Published in PloS one (31-07-2015)“…Wnt/beta-catenin signaling plays a central role in guiding the differentiation of the posterior parts of the primitive gut tube into intestinal structures in…”
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Efficient achievement of enteral autonomy facilitates resolution of liver injury in necrotizing enterocolitis induced short bowel syndrome
Published in Scientific reports (20-10-2022)“…Children with short bowel syndrome (SBS) are at high risk for intestinal failure associated liver disease (IFALD). The aim of this retrospective follow-up…”
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Infection Prevention and Management in Pediatric Short Bowel Syndrome
Published in Frontiers in pediatrics (30-06-2022)“…Short bowel syndrome (SBS) is a rare disease with potentially life-threatening consequences. In addition to intestinal failure-associated liver disease,…”
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Loss of ileum decreases serum fibroblast growth factor 19 in relation to liver inflammation and fibrosis in pediatric onset intestinal failure
Published in Journal of hepatology (01-06-2015)“…Background & Aims The pathogenesis of intestinal failure (IF) associated liver disease (IFALD) is uncertain, we therefore investigated the role of FGF19 and…”
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Outcomes of biliary atresia in the Nordic countries – a multicenter study of 158 patients during 2005–2016
Published in Journal of pediatric surgery (01-08-2018)“…Biliary atresia is the most common reason for newborn cholestasis and pediatric liver transplantation. Even after normalization of serum bilirubin after…”
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132. Robot assisted surgery – Gynaecology
Published in European journal of surgical oncology (01-09-2012)Get full text
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Intestinal Microbiota in Hirschsprung Disease
Published in Journal of pediatric gastroenterology and nutrition (01-11-2018)“…ABSTRACT Objectives: The aim of the study was to characterize the microbiota profiles of patients with Hirschsprung disease (HD) and to evaluate this in…”
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Systematic molecular and clinical analysis of uterine leiomyomas from fertile-aged women undergoing myomectomy
Published in Human reproduction (Oxford) (01-10-2020)“…What are the distributions and associated clinical characteristics of mediator complex subunit 12 (MED12), high mobility group AT-hook 2 (HMGA2) and fumarate…”
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Risk factors and outcomes of tapering surgery for small intestinal dilatation in pediatric short bowel syndrome
Published in Journal of pediatric surgery (01-07-2017)“…Abstract Background In remains unclear why in some short bowel syndrome (SBS) patients, the remaining small bowel (SB) dilates excessively leading to…”
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Featuring molecular regulation of bile acid homeostasis in pediatric short bowel syndrome
Published in Clinics and research in hepatology and gastroenterology (01-11-2023)“…•In SBS, enterohepatic circulation is interrupted due massive intestinal resection which associated with transcriptional evidence of increased hepatic…”
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Lower Urinary Tract Symptoms and Sexual Functions after Endorectal Pull-Through for Hirschsprung Disease: Controlled Long-Term Outcomes
Published in Journal of pediatric surgery (01-08-2017)“…Abstract Background/Purpose To define the prevalence of lower urinary tract symptoms (LUTS) and outcomes for sexual function after endorectal pull-through…”
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A population-based, complete follow-up of 146 consecutive patients after transanal mucosectomy for Hirschsprung disease
Published in Journal of pediatric surgery (01-10-2015)“…Abstract Objective The objective of the study is to define the population-based bowel functional outcomes and enterocolitis following transanal endorectal…”
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Development of an international core outcome set for treatment trials in necrotizing enterocolitis-a study protocol
Published in Current controlled trials in cardiovascular medicine (31-05-2023)“…Necrotizing enterocolitis (NEC) is the most lethal disease of the gastrointestinal tract of preterm infants. New and existing management strategies need…”
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Liver secretin receptor predicts portoenterostomy outcomes and liver injury in biliary atresia
Published in Scientific reports (04-05-2022)“…Biliary atresia (BA) is a chronic neonatal cholangiopathy characterized by fibroinflammatory bile duct damage. Reliable biomarkers for predicting native liver…”
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Postoperative outcome and survival in relation to small intestinal involvement of total colonic aganglionosis
Published in Journal of pediatric surgery (01-11-2015)“…Abstract Background The prognosis and treatment of total colonic aganglionosis (TCA) vary according to the presence and extent of small bowel involvement…”
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Risk of metabolic bone disease is increased both during and after weaning off parenteral nutrition in pediatric intestinal failure
Published in Hormone research in paediatrics (01-01-2013)“…To assess bone health in pediatric intestinal failure (IF). A population-based cohort of 41 IF patients (age 9.9 years) underwent evaluation of bone mineral…”
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