Search Results - "Pakarinen, P."

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    Bacterial translocation markers and toll‐like receptors in biliary atresia following successful portoenterostomy by Godbole, Nimish, Kyrönlahti, Antti, Hukkinen, Maria, Pihlajoki, Marjut, Heikinheimo, Markku, Pakarinen, Mikko P.

    Published in Acta Paediatrica (01-10-2023)
    “…Aim The gut–liver axis may contribute to pathophysiology of cholestatic liver disorders like biliary atresia (BA) by bacterial translocation (BT). Toll‐like…”
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    Journal Article
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    Long-term outcomes and quality of life in patients with Hirschsprung disease by Pakarinen, Mikko P, Mutanen, Annika

    Published in World Journal of Pediatric Surgery (09-10-2024)
    “…Although patients with Hirschsprung disease are mostly affected by imperfect bowel function and fecal control in the long term, they are also predisposed to…”
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    Journal Article Book Review
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    Persistent abnormal liver fibrosis after weaning off parenteral nutrition in pediatric intestinal failure by Mutanen, Annika, Lohi, Jouko, Heikkilä, Päivi, Koivusalo, Antti I., Rintala, Risto J., Pakarinen, Mikko P.

    Published in Hepatology (Baltimore, Md.) (01-08-2013)
    “…The aim of this study was to evaluate the long‐term effects of pediatric intestinal failure (IF) on liver histology. Altogether, 38 IF patients (median age:…”
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    Journal Article
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    Intestinal Commitment and Maturation of Human Pluripotent Stem Cells Is Independent of Exogenous FGF4 and R-spondin1 by Tamminen, Kaisa, Balboa, Diego, Toivonen, Sanna, Pakarinen, Mikko P, Wiener, Zoltan, Alitalo, Kari, Otonkoski, Timo

    Published in PloS one (31-07-2015)
    “…Wnt/beta-catenin signaling plays a central role in guiding the differentiation of the posterior parts of the primitive gut tube into intestinal structures in…”
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    Journal Article
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    Efficient achievement of enteral autonomy facilitates resolution of liver injury in necrotizing enterocolitis induced short bowel syndrome by Mutanen, Annika, Pöntinen, Ville, Gunnar, Riikka, Merras-Salmio, Laura, Pakarinen, Mikko P.

    Published in Scientific reports (20-10-2022)
    “…Children with short bowel syndrome (SBS) are at high risk for intestinal failure associated liver disease (IFALD). The aim of this retrospective follow-up…”
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    Journal Article
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    Infection Prevention and Management in Pediatric Short Bowel Syndrome by Merras-Salmio, Laura, Pakarinen, Mikko P.

    Published in Frontiers in pediatrics (30-06-2022)
    “…Short bowel syndrome (SBS) is a rare disease with potentially life-threatening consequences. In addition to intestinal failure-associated liver disease,…”
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    Journal Article
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    Loss of ileum decreases serum fibroblast growth factor 19 in relation to liver inflammation and fibrosis in pediatric onset intestinal failure by Mutanen, Annika, Lohi, Jouko, Heikkilä, Päivi, Jalanko, Hannu, Pakarinen, Mikko P

    Published in Journal of hepatology (01-06-2015)
    “…Background & Aims The pathogenesis of intestinal failure (IF) associated liver disease (IFALD) is uncertain, we therefore investigated the role of FGF19 and…”
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    Journal Article
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    Intestinal Microbiota in Hirschsprung Disease by Neuvonen, Malla I., Korpela, Katri, Kyrklund, Kristiina, Salonen, Anne, Vos, Willem, Rintala, Risto J., Pakarinen, Mikko P.

    “…ABSTRACT Objectives: The aim of the study was to characterize the microbiota profiles of patients with Hirschsprung disease (HD) and to evaluate this in…”
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    Journal Article
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    Systematic molecular and clinical analysis of uterine leiomyomas from fertile-aged women undergoing myomectomy by Äyräväinen, A, Pasanen, A, Ahvenainen, T, Heikkinen, T, Pakarinen, P, Härkki, P, Vahteristo, P

    Published in Human reproduction (Oxford) (01-10-2020)
    “…What are the distributions and associated clinical characteristics of mediator complex subunit 12 (MED12), high mobility group AT-hook 2 (HMGA2) and fumarate…”
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    Journal Article
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    Risk factors and outcomes of tapering surgery for small intestinal dilatation in pediatric short bowel syndrome by Hukkinen, Maria, Kivisaari, Reetta, Koivusalo, Antti, Pakarinen, Mikko P

    Published in Journal of pediatric surgery (01-07-2017)
    “…Abstract Background In remains unclear why in some short bowel syndrome (SBS) patients, the remaining small bowel (SB) dilates excessively leading to…”
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    Journal Article
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    Featuring molecular regulation of bile acid homeostasis in pediatric short bowel syndrome by Mutanen, Annika, Pakarinen, Mikko P

    “…•In SBS, enterohepatic circulation is interrupted due massive intestinal resection which associated with transcriptional evidence of increased hepatic…”
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    Journal Article
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    Lower Urinary Tract Symptoms and Sexual Functions after Endorectal Pull-Through for Hirschsprung Disease: Controlled Long-Term Outcomes by Neuvonen, Malla, Kyrklund, Kristiina, Taskinen, Seppo, Koivusalo, Antti, Rintala, Risto J, Pakarinen, Mikko P

    Published in Journal of pediatric surgery (01-08-2017)
    “…Abstract Background/Purpose To define the prevalence of lower urinary tract symptoms (LUTS) and outcomes for sexual function after endorectal pull-through…”
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    Journal Article
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    A population-based, complete follow-up of 146 consecutive patients after transanal mucosectomy for Hirschsprung disease by Neuvonen, Malla I, Kyrklund, Kristiina, Lindahl, Harry G, Koivusalo, Antti I, Rintala, Risto J, Pakarinen, Mikko P

    Published in Journal of pediatric surgery (01-10-2015)
    “…Abstract Objective The objective of the study is to define the population-based bowel functional outcomes and enterocolitis following transanal endorectal…”
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    Journal Article
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    Liver secretin receptor predicts portoenterostomy outcomes and liver injury in biliary atresia by Godbole, Nimish, Nyholm, Iiris, Hukkinen, Maria, Davidson, Joseph R., Tyraskis, Athanasios, Lohi, Jouko, Heikkilä, Päivi, Eloranta, Katja, Pihlajoki, Marjut, Davenport, Mark, Heikinheimo, Markku, Kyrönlahti, Antti, Pakarinen, Mikko P.

    Published in Scientific reports (04-05-2022)
    “…Biliary atresia (BA) is a chronic neonatal cholangiopathy characterized by fibroinflammatory bile duct damage. Reliable biomarkers for predicting native liver…”
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    Journal Article
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    Postoperative outcome and survival in relation to small intestinal involvement of total colonic aganglionosis by Hukkinen, Maria, Koivusalo, Antti, Merras-Salmio, Laura, Rintala, Risto J, Pakarinen, Mikko P

    Published in Journal of pediatric surgery (01-11-2015)
    “…Abstract Background The prognosis and treatment of total colonic aganglionosis (TCA) vary according to the presence and extent of small bowel involvement…”
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    Journal Article
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    Risk of metabolic bone disease is increased both during and after weaning off parenteral nutrition in pediatric intestinal failure by Mutanen, Annika, Mäkitie, Outi, Pakarinen, Mikko P

    Published in Hormone research in paediatrics (01-01-2013)
    “…To assess bone health in pediatric intestinal failure (IF). A population-based cohort of 41 IF patients (age 9.9 years) underwent evaluation of bone mineral…”
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    Journal Article