Search Results - "Pakarinen, Emmi"

CDNF and MANF regulate ER stress in a tissue-specific manner by Pakarinen, Emmi, Lindholm, Päivi, Saarma, Mart, Lindahl, Maria

“…Cerebral dopamine neurotrophic factor (CDNF) and mesencephalic astrocyte-derived neurotrophic factor (MANF) display cytoprotective effects in animal models of…”
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CDNF and MANF in the brain dopamine system and their potential as treatment for Parkinson's disease by Pakarinen, Emmi, Lindholm, Päivi

“…Parkinson's disease (PD) is a progressive neurodegenerative disease characterized by gradual loss of midbrain dopamine neurons, leading to impaired motor…”
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Deficiency of the ER-stress-regulator MANF triggers progressive outer hair cell death and hearing loss by Herranen, Anni, Ikäheimo, Kuu, Lankinen, Tuuli, Pakarinen, Emmi, Fritzsch, Bernd, Saarma, Mart, Lindahl, Maria, Pirvola, Ulla

“…The non-conventional neurotrophic factor mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER)-resident protein that…”
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CDNF Interacts with ER Chaperones and Requires UPR Sensors to Promote Neuronal Survival by Eesmaa, Ave, Yu, Li-Ying, Göös, Helka, Danilova, Tatiana, Nõges, Kristofer, Pakarinen, Emmi, Varjosalo, Markku, Lindahl, Maria, Lindholm, Päivi, Saarma, Mart

“…Cerebral dopamine neurotrophic factor (CDNF) is a neurotrophic factor that has beneficial effects on dopamine neurons in both in vitro and in vivo models of…”
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Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Is Highly Expressed in Mouse Tissues With Metabolic Function by Danilova, Tatiana, Galli, Emilia, Pakarinen, Emmi, Palm, Erik, Lindholm, Päivi, Saarma, Mart, Lindahl, Maria

“…Mesencephalic astrocyte-derived neurotrophic factor (MANF) and cerebral dopamine neurotrophic factor (CDNF) form a family of atypical growth factors discovered…”
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Cerebral dopamine neurotrophic factor–deficiency leads to degeneration of enteric neurons and altered brain dopamine neuronal function in mice by Lindahl, Maria, Chalazonitis, Alcmène, Palm, Erik, Pakarinen, Emmi, Danilova, Tatiana, Pham, Tuan D., Setlik, Wanda, Rao, Meenakshi, Võikar, Vootele, Huotari, Jatta, Kopra, Jaakko, Andressoo, Jaan-Olle, Piepponen, Petteri T., Airavaara, Mikko, Panhelainen, Anne, Gershon, Michael D., Saarma, Mart

“…Cerebral dopamine neurotrophic factor (CDNF) is neuroprotective for nigrostriatal dopamine neurons and restores dopaminergic function in animal models of…”
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Live-cell monitoring of protein localization to membrane rafts using protein-fragment complementation by Merezhko, Maria, Pakarinen, Emmi, Uronen, Riikka-Liisa, Huttunen, Henri J

“…The plasma membrane consists of a variety of discrete domains differing from the surrounding membrane in composition and properties. Selective partitioning of…”
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MANF Ablation Causes Prolonged Activation of the UPR without Neurodegeneration in the Mouse Midbrain Dopamine System by Pakarinen, Emmi, Danilova, Tatiana, Võikar, Vootele, Chmielarz, Piotr, Piepponen, Petteri, Airavaara, Mikko, Saarma, Mart, Lindahl, Maria

“…Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER) localized protein that regulates ER homeostasis and unfolded…”
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Poststroke delivery of MANF promotes functional recovery in rats by Mätlik, Kert, Anttila, Jenni E, Kuan-Yin, Tseng, Smolander, Olli-Pekka, Pakarinen, Emmi, Lehtonen, Leevi, Abo-Ramadan, Usama, Lindholm, Päivi, Zheng, Congjun, Harvey, Brandon, Arumäe, Urmas, Lindahl, Maria, Airavaara, Mikko

“…Stroke is the most common cause of adult disability in developed countries, largely because spontaneous recovery is often incomplete, and no pharmacological…”
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