Search Results - "Pak, Chwang Siek"

Identification of 3-Acetyl-2-aminoquinolin-4-one as a Novel, Nonpeptidic Scaffold for Specific Calpain Inhibitory Activity by Kang, Da-Hye, Jun, Kyu-Yeon, Lee, Jin Pyo, Pak, Chwang Siek, Na, Younghwa, Kwon, Youngjoo

“…A series of 3-acetyl-2-aminoquinolin-4-one derivatives selected from the Korean Chemical Bank were screened for calpain inhibitory activity by using a…”
Get full text

Efficient synthesis of arylsulfamides by reaction of amines with arylsulfamoyl imidazolium triflate by Lee, Hyeon Kyu, Bang, Miyeon, Pak, Chwang Siek

“…Arylsulfamoyl imidazolium triflates, readily prepared from the corresponding chlorides, react with amines under neutral conditions to form arylsulfamides in…”
Get full text

Facile Transformation of 2-Azetidinones to 2-Piperidones:  Application to the Synthesis of the Indolizidine Skeleton and (8S,8aS)-Perhydro-8-indolizinol by Lee, Hyeon Kyu, Chun, Jong Soo, Pak, Chwang Siek

“…The highly functionalized bicyclic lactam 7 was prepared from diolefinic-2-piperidone 18 by the use of ruthenium-catalyzed RCM, and in turn, 18 was derived via…”
Get full text

Facile transformation of 3,4-disubstituted 2-azetidinones to chiral 5,6-dihydro-2-pyridones by Lee, Hyeon Kyu, Chun, Jong Soo, Pak, Chwang Siek

“…Chiral 5,6-disubstituted-5,6-dihydro-2(1 H)-pyridones were prepared efficiently from readily accessible 3,4-disubstituted-2-azetidinones having preadjusted…”
Get full text

PTP-1B inhibitors: Cyclopenta[ d][1,2]-oxazine derivatives by Cho, Sung Yun, Baek, Ji Yoen, Han, Sang Sub, Kang, Seung Kyu, Ha, Jae Du, Ahn, Jin Hee, Lee, Jae Don, Kim, Kwang Rok, Cheon, Hyae Gyeong, Rhee, Sang Dal, Yang, Sung Don, Yon, Gyu Hwan, Pak, Chwang Siek, Choi, Joong-Kwon

“…A series of novel cyclopenta[ d][1,2]-oxazine derivatives was prepared and evaluated for their inhibitory activity toward protein tyrosine phosphatase 1B…”
Get full text

DEPROTECTION OF 2-PYRIDYL SULFONYL GROUP FROM PYRIDINE-2-SULFONAMIDES BY MAGNESIUM IN METHANOL by Pak, Chwang Siek, Lim, Dong Sung

“…Convenient deprotection of various pyridine-2-sulfonamides prepared by sulfonylation of primary and secondary amines with pyridine-2-sulfonylchloride was…”
Get full text

Reductive cleavage reaction of .gamma.-functionalized .alpha.,.beta.-unsaturated esters and halomethyls mediated with magnesium in methanol by Pak, Chwang Siek, Lee, Eun, Lee, Ge Hyeong

Get full text

Reductive Cyclization of Ketones Tethered to Activated Olefins Mediated by Magnesium in Methanol by Lee, Ge Hyeong, Choi, Eun Bok, Lee, Eun, Pak, Chwang Siek

Get full text

Total synthesis of (+)-preussin, a novel antifungal agent by Pak, Chwang Siek, Lee, Ge Hyeong

Get full text

The current status and future perspectives of studies of cannabinoid receptor 1 antagonists as anti-obesity agents by Lee, Hyeon-Kyu, Choi, Eun Bok, Pak, Chwang Siek

“…Since the discovery of rimonabant (Acomplia: 1), a large effort has been directed at the discovery of new, potent and selective CB(1)R antagonists that serve…”
Get more information

Total synthesis of (.+-.)-clavukerin A: a new trinorguaiane sesquiterpene. Biomimetic synthesis of (.+-.)-clavularin A from (.+-.)-clavukerin A by Kim, Sung Kee, Pak, Chwang Siek

Get full text

A convenient regioselective synthesis of substituted cycloheptenones by Pak, Chwang Siek, Kim, Sung Kee

Get full text

A methodology for the synthesis of highly functionalized 2- and 4-aminoquinoline derivatives by Hwang, Bo Hyun, Park, Sung Hee, Choi, Eun Bok, Pak, Chwang Siek, Lee, Hyeon Kyu

“…A methodology for the synthesis of 2- and 4-aminoquinoline derivatives, which takes advantage of selective activation of 2- or 4-substituent of…”
Get full text

Reactions of 1-Substituted 2,2-Difluorostyrenes with Dianions of 1,3-Diketones: Novel Synthesis of 4H-Pyran-4-one Derivatives by Tae Kim, Bum, Kyun Park, No, Siek Pak, Chwang, Sang Kim, Myong, Howa Jeong, In

Get full text

Facile conversion of 2-azetidinones to 2-piperidones: application to a formal synthesis of Prosopis and Cassia alkaloids by Lee, Hyeon Kyu, Chun, Jong Soo, Pak, Chwang Siek

“…Nonracemic 5,6-disubstituted 2-piperidones were prepared from readily accessible 3,4-disubstituted-2-azetidinones having pre-installed substituents by…”
Get full text

Facile transformation of 2-azetidinones to unsaturated ketones: application to the formal synthesis of sphingosine and phytosphingosine by Lee, Hyeon Kyu, Kim, Eun-Kyung, Pak, Chwang Siek

“…2-Azetidinones were smoothly transformed to unsaturated ketones through the ring opening of activated 2-azetidinone by phosphonate stabilized carbanion and…”
Get full text

Tandem in situ Generation of Azomethine Ylides and Base Sensitive Nitroethylene Dipolarophiles by Fejes, Imre, Tőke, László, Nyerges, Miklós, Pak, Chwang Siek

Get full text

Dye-sensitized photooxygenation of tert-butylpyrroles by Lightner, David A, Pak, Chwang-Siek

Get full text

A New Synthesis of 3,5-Diaryl-pyrrole-2-carboxylic Acids and Esters by Fejes, Imre, Tőke, László, Blaskó, Gábor, Nyerges, Miklós, Siek Pak, Chwang

“…A new two-step synthesis of pyrrole-2-carboxylic acids, steps via 1,3 dipolar cycloaddition of azomethine ylides to nitro-styrenes and oxidation of the…”
Get full text

Optical rotary dispersion studies. 129. Conformational isotope effects and octant contributions of methyl-d3 and methyl (carbon-13) groups in cyclohexanone by Lee, Shy-Fuh, Edgar, Mark, Pak, Chwang Siek, Barth, Guenter, Djerassi, Carl

Get full text