Treatment of facial lipoatrophy with polymethylmethacrylate among patients with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS): impact on the quality of life

Background The lipodystrophy syndrome is characterized by selective loss of subcutaneous fat on the face and extremities (lipoatrophy) and/or accumulation of fat around the neck, abdomen, and thorax (lipohypertrophy). The aim of this study has been to assess the impact of polymethylmethacrylate faci...

Full description

Saved in:

Bibliographic Details
Published in:	International journal of dermatology Vol. 53; no. 4; pp. 497 - 502
Main Authors:	Quintas, Rodrigo C. S., de França, Emmanuel R., de Petribú, Kátia C. L., Ximenes, Ricardo A. A., Quintas, Lóren F. F. M., Cavalcanti, Ernando L. F., Kitamura, Marco A. P., Magalhães, Kássia A. A., Paiva, Késsia C. F., Filho, Demócrito B. Miranda
Format:	Journal Article
Language:	English
Published:	England Blackwell Publishing Ltd 01-04-2014
Subjects:	Acquired Immunodeficiency Syndrome - complications Acquired Immunodeficiency Syndrome - drug therapy Adult Aged Anti-HIV Agents - therapeutic use Depression - psychology Dermatologic Agents - administration & dosage Dermatologic Agents - adverse effects Ecchymosis - chemically induced Edema - chemically induced Face Female HIV-Associated Lipodystrophy Syndrome - psychology HIV-Associated Lipodystrophy Syndrome - therapy Human immunodeficiency virus Humans Male Middle Aged Polymethyl Methacrylate - administration & dosage Polymethyl Methacrylate - adverse effects Psychiatric Status Rating Scales Quality of Life Skin Diseases - chemically induced Surveys and Questionnaires Young Adult
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Background The lipodystrophy syndrome is characterized by selective loss of subcutaneous fat on the face and extremities (lipoatrophy) and/or accumulation of fat around the neck, abdomen, and thorax (lipohypertrophy). The aim of this study has been to assess the impact of polymethylmethacrylate facial treatment on quality of life, self‐perceived facial image, and the severity of depressive symptoms in patients living with HIV/AIDS. Methods A non‐randomized before and after interventional study was developed. Fifty‐one patients underwent facial filling. The self‐perceived quality of life, facial image, and degree of depressive symptoms were measured by the Short‐Form 36 and HIV/AIDS – Targeted quality of life questionnaires, by a visual analogue scale and by the Beck depression inventory, respectively, before and three months after treatment. Results Six of the eight domains of Short‐Form 36 and eight of the nine dimensions of the HIV/AIDS – Targeted quality of life questionnaires, together with the visual analogue scale and by the Beck depression inventory scores, revealed a statistically significant improvement. The only adverse effects registered were edema and ecchymosis. Conclusion The treatment of facial lipoatrophy improved the self‐perceived quality of life and facial image as well as any depressive symptoms among patients with HIV/AIDS.
Bibliography:	istex:C72C4E7CDC0C490B9AA000FE4C24B38B8F0BFFCA ArticleID:IJD12400 ark:/67375/WNG-FVWMLQ3K-7 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23
ISSN:	0011-9059 1365-4632
DOI:	10.1111/ijd.12400