Search Results - "Paiva, Igor M."

Design and evaluation of albumin nanoparticles for the delivery of a novel β-tubulin polymerization inhibitor by Spada, Alessandra, Emami, Jaber, Sanaee, Foroughalsadat, Aminpour, Maral, Paiva, Igor M, Tuszynski, Jack, Lavasanifar, Afsaneh

“…The ultimate goal of this study is to develop a novel delivery system for a new potent cytotoxic compound, CCI-001, with anti-b tubulin activity, so that the…”
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Development of Self-Associating SN-38-Conjugated Poly(ethylene oxide)-Poly(ester) Micelles for Colorectal Cancer Therapy by Sadat, Sams M. A., Vakili, Mohammad Reza, Paiva, Igor M., Weinfeld, Michael, Lavasanifar, Afsaneh

“…The clinical use of 7-ethyl-10-hydroxy-camptothecin (SN-38), which is the active metabolite of irinotecan, has been hampered because of its practical…”
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Nano-Delivery of a Novel Inhibitor of Polynucleotide Kinase/Phosphatase (PNKP) for Targeted Sensitization of Colorectal Cancer to Radiation-Induced DNA Damage by Sadat, Sams M A, Wuest, Melinda, Paiva, Igor M, Munira, Sirazum, Sarrami, Nasim, Sanaee, Forughalsadat, Yang, Xiaoyan, Paladino, Marco, Binkhathlan, Ziyad, Karimi-Busheri, Feridoun, Martin, Gary R, Jirik, Frank R, Murray, David, Gamper, Armin M, Hall, Dennis G, Weinfeld, Michael, Lavasanifar, Afsaneh

“…Inhibition of the DNA repair enzyme polynucleotide kinase/phosphatase (PNKP) increases the sensitivity of cancer cells to DNA damage by ionizing radiation…”
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Traceable PEO-poly(ester) micelles for breast cancer targeting: The effect of core structure and targeting peptide on micellar tumor accumulation by Garg, Shyam M., Paiva, Igor M., Vakili, Mohammad R., Soudy, Rania, Agopsowicz, Kate, Soleimani, Amir H., Hitt, Mary, Kaur, Kamaljit, Lavasanifar, Afsaneh

“…Traceable poly(ethylene oxide)-poly(ester) micelles were developed through chemical conjugation of a near-infrared (NIR) dye to the poly(ester) end by click…”
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A synthetically lethal nanomedicine delivering novel inhibitors of polynucleotide kinase 3′-phosphatase (PNKP) for targeted therapy of PTEN-deficient colorectal cancer by Sadat, Sams M.A., Paiva, Igor M., Shire, Zahra, Sanaee, Forughalsadat, Morgan, Timothy D.R., Paladino, Marco, Karimi-Busheri, Feridoun, Mani, Rajam S., Martin, Gary R., Jirik, Frank R., Hall, Dennis G., Weinfeld, Michael, Lavasanifar, Afsaneh

“…Phosphatase and TENsin homolog deleted on chromosome 10 (PTEN) is a major tumor-suppressor protein that is lost in up to 75% of aggressive colorectal cancers…”
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Micellar nano-carriers for the delivery of STAT3 dimerization inhibitors to melanoma by Soleimani, Amir H., Garg, Shyam M., Paiva, Igor M., Vakili, Mohammad R., Alshareef, Abdulraheem, Huang, Yung-Hsing, Molavi, Ommoleila, Lai, Raymond, Lavasanifar, Afsaneh

“…The objective of this research was to develop polymeric micellar formulations of inhibitors of signal transducer and activator of transcription 3 (STAT3)…”
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NANOPARTICLES FOR USE IN CARDIOMYOPATHY: MAKING OLD DRUGS DO NEW TRICKS by Youker, Keith, Paiva, Igor M., Lavasanifar, Afsaneh, Bolton, Anthony, Torre-Amione, Guillermo

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