Search Results - "Paiva, Claudia N"

Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice by Monnerat, Gustavo, Alarcón, Micaela L., Vasconcellos, Luiz R., Hochman-Mendez, Camila, Brasil, Guilherme, Bassani, Rosana A., Casis, Oscar, Malan, Daniela, Travassos, Leonardo H., Sepúlveda, Marisa, Burgos, Juan Ignacio, Vila-Petroff, Martin, Dutra, Fabiano F., Bozza, Marcelo T., Paiva, Claudia N., Carvalho, Adriana Bastos, Bonomo, Adriana, Fleischmann, Bernd K., de Carvalho, Antonio Carlos Campos, Medei, Emiliano

“…Diabetes mellitus (DM) encompasses a multitude of secondary disorders, including heart disease. One of the most frequent and potentially life threatening…”
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Heme oxygenase-1 in protozoan infections: A tale of resistance and disease tolerance by Silva, Rafael C. M. C, Travassos, Leonardo H, Paiva, Claudia N, Bozza, Marcelo T

“…Heme oxygenase (HO-1) mediates the enzymatic cleavage of heme, a molecule with proinflammatory and prooxidant properties. HO-1 activity deeply impacts host…”
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ROS and Trypanosoma cruzi: Fuel to infection, poison to the heart by Paiva, Claudia N, Medei, Emiliano, Bozza, Marcelo T

“…The activation of macrophage respiratory burst in response to infection with Trypanosoma cruzi inflicts oxidative damage to the host's tissues. For decades,…”
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Resveratrol Reverses Functional Chagas Heart Disease in Mice by Vilar-Pereira, Glaucia, Carneiro, Vitor C, Mata-Santos, Hilton, Vicentino, Amanda R R, Ramos, Isalira P, Giarola, Naira L L, Feijó, Daniel F, Meyer-Fernandes, José R, Paula-Neto, Heitor A, Medei, Emiliano, Bozza, Marcelo T, Lannes-Vieira, Joseli, Paiva, Claudia N

“…Chronic chagasic cardiomyopathy (CCC) develops years after acute infection by Trypanosoma cruzi and does not improve after trypanocidal therapy, despite…”
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Author Correction: Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice by Monnerat, Gustavo, Alarcón, Micaela L., Vasconcellos, Luiz R., Hochman-Mendez, Camila, Brasil, Guilherme, Bassani, Rosana A., Casis, Oscar, Malan, Daniela, Travassos, Leonardo H., Sepúlveda, Marisa, Burgos, Juan Ignacio, Vila-Petroff, Martin, Dutra, Fabiano F., Bozza, Marcelo T., Paiva, Claudia N., Carvalho, Adriana Bastos, Bonomo, Adriana, Fleischmann, Bernd K., de Carvalho, Antonio Carlos Campos, Medei, Emiliano

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Are reactive oxygen species always detrimental to pathogens? by Paiva, Claudia N, Bozza, Marcelo T

“…Reactive oxygen species (ROS) are deadly weapons used by phagocytes and other cell types, such as lung epithelial cells, against pathogens. ROS can kill…”
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The Paradoxical Leishmanicidal Effects of Superoxide Dismutase (SOD)-Mimetic Tempol in Leishmania braziliensis Infection in vitro by Oliveira, Laíse B, Celes, Fabiana S, Paiva, Claudia N, de Oliveira, Camila I

“…Leishmaniasis is an infectious disease caused by protozoans of the genus . The macrophage is the resident cell in which the parasite replicates and it is…”
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Hydroxychloroquine in Nonhospitalized Adults With Early COVID-19 by Paiva, Claudia N, Tausk, Daniel V

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Unraveling the lethal synergism between Trypanosoma cruzi infection and LPS: A role for increased macrophage reactivity by Paiva, Cláudia N., Arras, Rosa H., Lessa, Luiz P., Gibaldi, Daniel, Alves, Letícia, Metz, Christine N., Gazzinelli, Ricardo, Pyrrho, Alexandre S., Lannes‐Vieira, Joseli, Bozza, Marcelo T.

“…Various infections sensitize to lethal shock by promoting hyperactivation of macrophages to LPS stimulation. Although macrophages are thought to be deactivated…”
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Macrophage Migration Inhibitory Factor in Protozoan Infections by Bozza, Marcelo T., Martins, Yuri C., Carneiro, Letícia A. M., Paiva, Claudia N.

“…Macrophage migration inhibitory factor (MIF) is a cytokine that plays a central role in immune and inflammatory responses. In the present paper, we discussed…”
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Migration inhibitory factor (MIF) released by macrophages upon recognition of immune complexes is critical to inflammation in Arthus reaction by Paiva, Claudia N, Arras, Rosa H, Magalhães, Elisabeth S, Alves, Letícia S, Lessa, Luiz Paulo, Silva, Maria Helena, Ejzemberg, Regina, Canetti, Cláudio, Bozza, Marcelo T

“…Deposition of immune complexes (IC) triggers FcγR‐dependent inflammation, leading to tissue damage in rheumatoid arthritis, systemic lupus erythematous, immune…”
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The Role of MIF on Eosinophil Biology and Eosinophilic Inflammation by Bozza, Marcelo T., Lintomen, Leticia, Kitoko, Jamil Z., Paiva, Cláudia N., Olsen, Priscilla C.

“…Macrophage migration inhibitory factor (MIF) is an inflammatory cytokine that participates in innate and adaptive immune responses. MIF contributes to the…”
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Mitochondrial Reactive Oxygen Species Participate in Signaling Triggered by Heme in Macrophages and upon Hemolysis by Prestes, Elisa B, Alves, Letícia S, Rodrigues, Danielle A S, Dutra, Fabianno F, Fernandez, Patricia L, Paiva, Claudia N, Kagan, Jonathan C, Bozza, Marcelo T

“…Hemolysis causes an increase of intravascular heme, oxidative damage, and inflammation in which macrophages play a critical role. In these cells, heme can act…”
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Heart function enhancement with Nrf2-activating antioxidant in acute Y-strain Chagas disease, not in chronic Colombian or Y-strain by Mata-Santos, Hilton Antônio, Sousa Oliveira, Camila Victória, Feijo, Daniel F., Vanzan, Daniel Figueiredo, Villar-Pereira, Glaucia, Ramos, Isalira P., Carneiro, Vitor Coutinho, Moreno-Loaiza, Oscar, Silverio, Jaline Coutinho, Lannes-Vieira, Joseli, Medei, Emiliano, Bozza, Marcelo T., Paiva, Claudia N.

“…Oxidative stress promotes T . cruzi growth and development of chronic Chagas heart dysfunction. However, the literature contains gaps that must be fulfilled,…”
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Cardiac arrhythmias after renal I/R depend on IL-1β by Alarcon, Maria Micaela Lopez, Trentin-Sonoda, Mayra, Panico, Karine, Schleier, Ygor, Duque, Thabata, Moreno-Loaiza, Oscar, de Yurre, Ainhoa Rodriguez, Ferreira, Fabianno, Caio-Silva, Wellington, Coury, Pedrosa Roberto, Paiva, Claudia N., Medei, Emiliano, Carneiro-Ramos, Marcela Sorelli

“…Cardiac arrhythmias are one of the most important remote complications after kidney injury. Renal ischemia reperfusion (I/R) is a major cause of acute renal…”
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Oxidative stress fuels Trypanosoma cruzi infection in mice by Paiva, Claudia N, Feijó, Daniel F, Dutra, Fabianno F, Carneiro, Vitor C, Freitas, Guilherme B, Alves, Letícia S, Mesquita, Jacilene, Fortes, Guilherme B, Figueiredo, Rodrigo T, Souza, Heitor S P, Fantappié, Marcelo R, Lannes-Vieira, Joseli, Bozza, Marcelo T

“…Oxidative damage contributes to microbe elimination during macrophage respiratory burst. Nuclear factor, erythroid-derived 2, like 2 (NRF2) orchestrates…”
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Toll-Like Receptor 4 and NLRP3 Caspase 1- Interleukin-1β-Axis are Not Involved in Colon Ascendens Stent Peritonitis-Associated Heart Disease by Alarcón, Maria Micaela Lopez, Ruocco, Julieta Fernández, Ferreira, Fabiano, Paula-Neto, Heitor A, Sepúlveda, Marisa, Vila Petroff, Martín, Carvalho, Adriana Bastos, Ramos, Isalira Peroba, Branda, Hugo Justino, Paiva, Claudia N, Medei, Emiliano

“…ABSTRACTHemodynamic collapse and myocardial dysfunction are among the major causes of death in severe sepsis. The purpose of this study was to assess the role…”
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Silymarin Reduces Profibrogenic Cytokines and Reverses Hepatic Fibrosis in Chronic Murine Schistosomiasis by MATA-SANTOS, Hílton Antônio, DUTRA, Fabianno Ferreira, DOS SANTOS PYRRHO, Alexandre, ROCHA, Carolina Carneiro, LINO, Fabiana Gonçalves, XAVIER, Fabiola Ramos, CHINALIA, Leandro Andrade, HOSSY, Bryan Hudson, CASTELO-BRANCO, Morgana Teixeira Lima, TEODORO, Anderson Junger, PAIVA, Claudia N

“…In chronic schistosomiasis, hepatic fibrosis is linked to the portal hypertension that causes morbidity in Schistosoma mansoni infection. Silymarin (SIL) is a…”
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Heme Amplifies the Innate Immune Response to Microbial Molecules through Spleen Tyrosine Kinase (Syk)-dependent Reactive Oxygen Species Generation by Fernandez, Patricia L., Dutra, Fabianno F., Alves, Letícia, Figueiredo, Rodrigo T., Mourão-Sa, Diego, Fortes, Guilherme B., Bergstrand, Sophie, Lönn, David, Cevallos, Ricardo R., Pereira, Renata M.S., Lopes, Ulisses G., Travassos, Leonardo H., Paiva, Claudia N., Bozza, Marcelo T.

“…Infectious diseases that cause hemolysis are among the most threatening human diseases, because of severity and/or global distribution. In these conditions,…”
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Autoantibodies with beta-adrenergic activity from chronic chagasic patients induce cardiac arrhythmias and early afterdepolarization in a drug-induced LQT2 rabbit hearts by Jiménez, Marco Antonio Vidal, Nascimento, José H.M, Monnerat, Gustavo, Maciel, Leonardo, Paiva, Claudia N, Pedrosa, Roberto Coury, Campos de Carvalho, Antonio C, Medei, Emiliano

“…Abstract Background Cardiac arrhythmias are one of the main causes of death in ChCP and other dilated cardiomyopathies. Previous studies demonstrated that…”
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