Search Results - "Pais, Pedro"

Saccharomyces boulardii: What Makes It Tick as Successful Probiotic? by Pais, Pedro, Almeida, Vanda, Yilmaz, Melike, Teixeira, Miguel C

“…Saccharomyces boulardii is a probiotic yeast often used for the treatment of GI tract disorders such as diarrhea symptoms. It is genetically close to the model…”
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YEASTRACT+: a portal for cross-species comparative genomics of transcription regulation in yeasts by Monteiro, Pedro T, Oliveira, Jorge, Pais, Pedro, Antunes, Miguel, Palma, Margarida, Cavalheiro, Mafalda, Galocha, Mónica, Godinho, Cláudia P, Martins, Luís C, Bourbon, Nuno, Mota, Marta N, Ribeiro, Ricardo A, Viana, Romeu, Sá-Correia, Isabel, Teixeira, Miguel C

“…Abstract The YEASTRACT+ information system (http://YEASTRACT-PLUS.org/) is a wide-scope tool for the analysis and prediction of transcription regulatory…”
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YEASTRACT: an upgraded database for the analysis of transcription regulatory networks in Saccharomyces cerevisiae by Teixeira, Miguel C, Monteiro, Pedro T, Palma, Margarida, Costa, Catarina, Godinho, Cláudia P, Pais, Pedro, Cavalheiro, Mafalda, Antunes, Miguel, Lemos, Alexandre, Pedreira, Tiago, Sá-Correia, Isabel

“…Abstract The YEAst Search for Transcriptional Regulators And Consensus Tracking (YEASTRACT-www.yeastract.com) information system has been, for 11 years, a key…”
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Divergent Approaches to Virulence in C. albicans and C. glabrata : Two Sides of the Same Coin by Galocha, Mónica, Pais, Pedro, Cavalheiro, Mafalda, Pereira, Diana, Viana, Romeu, Teixeira, Miguel C

“…and are the two most prevalent etiologic agents of candidiasis worldwide. Although both are recognized as pathogenic, their choice of virulence traits is…”
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Evaluating optimizations that reduce global memory accesses of stencil computations in GPGPUs by Carrijo Nasciutti, Thiago, Panetta, Jairo, Pais Lopes, Pedro

“…Summary This work compares the performance of optimizations that transform replicated global memory accesses into local memory accesses on 3D stencil…”
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Candida glabrata Transcription Factor Rpn4 Mediates Fluconazole Resistance through Regulation of Ergosterol Biosynthesis and Plasma Membrane Permeability by Pais, Pedro, Califórnia, Raquel, Galocha, Mónica, Viana, Romeu, Ola, Mihaela, Cavalheiro, Mafalda, Takahashi-Nakaguchi, Azusa, Chibana, Hiroji, Butler, Geraldine, Teixeira, Miguel C

“…The ability to acquire azole resistance is an emblematic trait of the fungal pathogen Understanding the molecular basis of azole resistance in this pathogen is…”
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The PathoYeastract database: an information system for the analysis of gene and genomic transcription regulation in pathogenic yeasts by Monteiro, Pedro Tiago, Pais, Pedro, Costa, Catarina, Manna, Sauvagya, Sá-Correia, Isabel, Teixeira, Miguel Cacho

“…We present the PATHOgenic YEAst Search for Transcriptional Regulators And Consensus Tracking (PathoYeastract - http://pathoyeastract.org) database, a tool for…”
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Membrane Proteome-Wide Response to the Antifungal Drug Clotrimazole in Candida glabrata: Role of the Transcription Factor CgPdr1 and the Drug:H+ Antiporters CgTpo1_1 and CgTpo1_2 by Pais, Pedro, Costa, Catarina, Pires, Carla, Shimizu, Kiminori, Chibana, Hiroji, Teixeira, Miguel C.

“…Azoles are widely used antifungal drugs. This family of compounds includes triazoles, mostly used in the treatment of systemic infections, and imidazoles, such…”
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Chronic nasopharyngeal and otitis media tuberculosis: diagnosis and management difficulties by Pais, José Pedro, Caçador, Maria, Mourato, Teresa, Paço, João

“…Nasopharyngeal and otitis media tuberculosis are rare extrapulmonary manifestations of infection. We present a case of a middle-aged woman with manifestations…”
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New Mechanisms of Flucytosine Resistance in C. glabrata Unveiled by a Chemogenomics Analysis in S. cerevisiae by Costa, Catarina, Ponte, Andreia, Pais, Pedro, Santos, Rui, Cavalheiro, Mafalda, Yaguchi, Takashi, Chibana, Hiroji, Teixeira, Miguel Cacho

“…5-Flucytosine is currently used as an antifungal drug in combination therapy, but fungal pathogens are rapidly able to develop resistance against this drug,…”
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Microevolution of the pathogenic yeasts Candida albicans and Candida glabrata during antifungal therapy and host infection by Pais, Pedro, Galocha, Mónica, Viana, Romeu, Cavalheiro, Mafalda, Pereira, Diana, Teixeira, Miguel Cacho

“…Infections by the pathogenic yeasts and are among the most common fungal diseases. The success of these species as human pathogens is contingent on their…”
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Fluoroquinolone Derivatives in the Treatment of Mycobacterium tuberculosis Infection by Pais, João Pedro, Policarpo, Margarida, Pires, David, Francisco, Ana Paula, Madureira, Ana Margarida, Testa, Bernard, Anes, Elsa, Constantino, Luís

“…Tuberculosis (TB) is currently one of the leading causes of death due to infective agents, and the growing rate of multidrug-resistant tuberculosis (MDR TB)…”
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Membrane Proteomics Analysis of the Candida glabrata Response to 5-Flucytosine: Unveiling the Role and Regulation of the Drug Efflux Transporters CgFlr1 and CgFlr2 by Pais, Pedro, Pires, Carla, Costa, Catarina, Okamoto, Michiyo, Chibana, Hiroji, Teixeira, Miguel C

“…Resistance to 5-flucytosine (5-FC), used as an antifungal drug in combination therapy, compromises its therapeutic action. In this work, the response of the…”
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Role of CgTpo4 in Polyamine and Antimicrobial Peptide Resistance: Determining Virulence in Candida glabrata by Cavalheiro, Mafalda, Romão, Daniela, Santos, Rui, Mil-Homens, Dalila, Pais, Pedro, Costa, Catarina, Galocha, Mónica, Pereira, Diana, Takahashi-Nakaguchi, Azusa, Chibana, Hiroji, Fialho, Arsénio M, Teixeira, Miguel C

“…is an emerging fungal pathogen whose success depends on its ability to resist antifungal drugs but also to thrive against host defenses. In this study, the…”
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Multiple genome analysis of Candida glabrata clinical isolates renders new insights into genetic diversity and drug resistance determinants by Pais, Pedro, Galocha, Mónica, Takahashi-Nakaguchi, Azusa, Chibana, Hiroji, Teixeira, Miguel C.

“…The emergence of drug resistance significantly hampers the treatment of human infections, including those caused by fungal pathogens such as Candida species…”
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A new regulator in the crossroads of oxidative stress resistance and virulence in Candida glabrata: The transcription factor CgTog1 by Pais, Pedro, Vagueiro, Susana, Mil-Homens, Dalila, Pimenta, Andreia I., Viana, Romeu, Okamoto, Michiyo, Chibana, Hiroji, Fialho, Arsénio M., Teixeira, Miguel C.

“…Candida glabrata is a prominent pathogenic yeast which exhibits a unique ability to survive the harsh environment of host immune cells. In this study, we…”
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Transcriptional Control of Drug Resistance, Virulence and Immune System Evasion in Pathogenic Fungi: A Cross-Species Comparison by Pais, Pedro, Costa, Catarina, Cavalheiro, Mafalda, Romão, Daniela, Teixeira, Miguel C

“…Transcription factors are key players in the control of the activation or repression of gene expression programs in response to environmental stimuli. The…”
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A New Determinant of Candida glabrata Virulence: The Acetate Exporter CgDtr1 by Romão, Daniela, Cavalheiro, Mafalda, Mil-Homens, Dalila, Santos, Rui, Pais, Pedro, Costa, Catarina, Takahashi-Nakaguchi, Azusa, Fialho, Arsénio M, Chibana, Hiroji, Teixeira, Miguel C

“…Persistence and virulence of infections are multifactorial phenomena, whose understanding is crucial to design more suitable therapeutic strategies. In this…”
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Genomic evolution towards azole resistance in Candida glabrata clinical isolates unveils the importance of CgHxt4/6/7 in azole accumulation by Galocha, Mónica, Viana, Romeu, Pais, Pedro, Silva-Dias, Ana, Cavalheiro, Mafalda, Miranda, Isabel M., Van Ende, Mieke, Souza, Caio S., Costa, Catarina, Branco, Joana, Soares, Cláudio M., Van Dijck, Patrick, Rodrigues, Acácio G., Teixeira, Miguel C.

“…The increasing prevalence of candidosis caused by Candida glabrata is related to its ability to acquire azole resistance. Although azole resistance mechanisms…”
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Characterization of the Candida glabrata Transcription Factor CgMar1: Role in Azole Susceptibility by Pais, Pedro, Galocha, Mónica, Califórnia, Raquel, Viana, Romeu, Ola, Mihaela, Okamoto, Michiyo, Chibana, Hiroji, Butler, Geraldine, Teixeira, Miguel C

“…The prevalence of antifungal resistance in , especially against azole drugs, results in difficult-to-treat and potentially life-threatening infections…”
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