Search Results - "Pais, A."

Pseudomonas aeruginosa infection in cystic fibrosis lung disease and new perspectives of treatment: a review by Gaspar, M. C., Couet, W., Olivier, J.-C., Pais, A. A. C. C., Sousa, J. J. S.

“…Cystic fibrosis (CF) is a complex inherited disease which affects many organs, including the pancreas and liver, gastrointestinal tract and reproductive…”
Get full text

Skin cancer and new treatment perspectives: A review by Simões, M.C.F, Sousa, J.J.S, Pais, A.A.C.C

“…Highlights • State of the art: technologies that may fit in the clinical practice are overviewed. • New treatment options, prompted by the growing incidence of…”
Get full text

DNA-based nanoscaffolds as vehicles for 5-fluoro-2'-deoxyuridine oligomers in colorectal cancer therapy by Jorge, A F, Aviñó, A, Pais, A A C C, Eritja, R, Fàbrega, C

“…Fluoropyrimidines, such as 5-fluorouracil (5-FU) and related prodrugs, are considered one of the most successful agents in the treatment of colorectal cancer,…”
Get more information

Advances in Computational Techniques for Bio-Inspired Cellular Materials in the Field of Biomechanics: Current Trends and Prospects by Pais, A I, Belinha, J, Alves, J L

“…Cellular materials have a wide range of applications, including structural optimization and biomedical applications. Due to their porous topology, which…”
Get full text

Co-encapsulating nanostructured lipid carriers for transdermal application: From experimental design to the molecular detail by Vitorino, C., Almeida, J., Gonçalves, L.M., Almeida, A.J., Sousa, J.J., Pais, A.A.C.C.

“…Co-encapsulation of drugs directed at commonly associated diseases provides a convenient means for administration, especially if transdermally delivered. In…”
Get full text

Expanding Transdermal Delivery with Lipid Nanoparticles: A New Drug-in-NLC-in-Adhesive Design by Mendes, M, Nunes, S. C. C, Sousa, J. J, Pais, A. A. C. C, Vitorino, C

“…A monolithic drug-in-NLC-in-adhesive transdermal patch, with a novel design, was developed for codelivery of olanzapine (OL) and simvastatin (SV)…”
Get full text

Comparing behavior following binge ethanol in adolescent and adult DBA/2 J mice by Bent, Maria Alexis M., Pais, A. Christian, Wolstenholme, Jennifer T.

“…The adolescent brain undergoes maturation in areas critically involved in reward, addiction, and memory. Adolescents consume alcohol more than any other drug,…”
Get full text

Fluorescence Enhancement of a Cationic Fluorene–Phenylene Conjugated Polyelectrolyte Induced by Nonionic n‑Alkyl Polyoxyethylene Surfactants by Monteserín, María, Burrows, Hugh D, Valente, Artur J. M, Pais, A. A. C. C, Di Paolo, Roberto E, Maçanita, Antonio L, Tapia, María J

“…The modulation of conjugated polyelectrolyte fluorescence response by nonionic surfactants is dependent on the structures of the surfactant and polymer,…”
Get full text

A bio-inspired remodelling algorithm combined with a natural neighbour meshless method to obtain optimized functionally graded materials by Pais, A.I., Alves, J.L., Belinha, J.

“…Recent developments suggest the use of triply periodic minimal surfaces (such as the gyroid) as a possibility for bone tissue scaffold. Moreover, through…”
Get full text

Diving into Batch-to-Batch Variability of Topical Products-a Regulatory Bottleneck by Miranda, Margarida, Cova, Tânia, Augusto, Cátia, Pais, Alberto A. C. C., Cardoso, Catarina, Vitorino, Carla

“…Purpose Following the recent European Medicine Agency (EMA) draft guideline on quality and equivalence of topical products, a modular framework for…”
Get full text

Removal of Pharmaceuticals from Water by Free and Imobilised Microalgae by Encarnação, Telma, Palito, Cátia, Pais, Alberto A C C, Valente, Artur J M, Burrows, Hugh D

“…Pharmaceuticals and their metabolites are released into the environment by domestic, hospital, and pharmaceutical industry wastewaters. Conventional wastewater…”
Get full text

Machine Learning-Based Prediction of Reduction Potentials for Pt IV Complexes by Vigna, V, Cova, T F G G, Nunes, S C C, Pais, A A C C, Sicilia, E

“…Some of the well-known drawbacks of clinically approved Pt complexes can be overcome using six-coordinate Pt complexes as inert prodrugs, which release the…”
Get full text

Machine Learning-Based Prediction of Reduction Potentials for PtIV Complexes by Vigna, V., Cova, T. F. G. G., Nunes, S. C. C., Pais, A. A. C. C., Sicilia, E.

“…Some of the well-known drawbacks of clinically approved PtII complexes can be overcome using six-coordinate PtIV complexes as inert prodrugs, which release the…”
Get full text

Starch-based Pickering emulsions for topical drug delivery: A QbD approach by Marto, J., Gouveia, L., Jorge, I.M., Duarte, A., Gonçalves, L.M., Silva, S.M.C., Antunes, F., Pais, A.A.C.C., Oliveira, E., Almeida, A.J., Ribeiro, H.M.

“…•A QbD approach was successfully applied to obtain Starch Pickering emulsions.•Formulation and process parameters allowed modulating droplet size.•Starch…”
Get full text

Short Timescale Core Dynamics: Theory and Observations by Finlay, C. C., Dumberry, M., Chulliat, A., Pais, M. A.

“…Fluid motions in the Earth’s core produce changes in the geomagnetic field (secular variation) and are also an important ingredient in the planet’s rotational…”
Get full text

Quasi-geostrophic flows responsible for the secular variation of the Earth's magnetic field by Pais, M. A., Jault, D.

“…We present core flows constructed from high resolution secular variation (SV) models for the epochs 2001, 2002.5 and 2004, assuming that these flows are…”
Get full text

DNA adsorption on like-charged surfaces mediated by polycations by Nunes, Sandra C.C., Pais, A.A.C.C.

“…[Display omitted] •Electrostatic interactions govern polyplex adsorption to the cell membrane surface;•Polyanion/surface like-charge attraction increases with…”
Get full text

Deep Learning for Deep Chemistry: Optimizing the Prediction of Chemical Patterns by Cova, Tânia F G G, Pais, Alberto A C C

“…Computational Chemistry is currently a synergistic assembly between calculations, simulation, machine learning (ML) and optimization strategies for describing,…”
Get full text

Can lipid nanoparticles improve intestinal absorption? by Mendes, M., Soares, H.T, Arnaut, L.G, Sousa, J.J, Pais, A.A.C.C., Vitorino, C.

“…[Display omitted] Lipid nanoparticles and their multiple designs have been considered appealing nanocarrier systems. Bringing the benefits of these nanosystems…”
Get full text

Cardiac papillary fibroelastoma – different locations, the same suspect by Pais, João A., Sampaio, Francisco, Ribeiro, José, Fontes-Carvalho, Ricardo

Get full text