Search Results - "Pairet, M"

Distinct isoforms (COX-1 and COX-2) of cyclooxygenase: possible physiological and therapeutic implications by Pairet, M, Engelhardt, G

“…The discovery of an inducible isoform of cyclooxygenase (COX-2) requires a refinement of the theory that inhibition of cyclooxygenase activity explains both…”
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Experimental models used to investigate the differential inhibition of cyclooxygenase-1 and cyclooxygenase-2 by non-steroidal anti-inflammatory drugs by Pairet, M, van Ryn, J

“…Numerous in vitro assays have been developed for testing and comparing the relative inhibitory activities of non-steroidal anti-inflammatory drugs against…”
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Effects of caffeine and paracetamol alone or in combination with acetylsalicylic acid on prostaglandin E2 synthesis in rat microglial cells by FIEBICH, B. L, LIEB, K, HÜLL, M, AICHER, B, VAN RYN, J, PAIRET, M, ENGELHARDT, G

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Differential inhibition of cyclooxygenases-1 and -2 by meloxicam and its 4'-isomer by Pairet, M, van Ryn, J, Schierok, H, Mauz, A, Trummlitz, G, Engelhardt, G

“…Two structurally related compounds, meloxicam (Mel) and its structural 4'-isomer (4'-Mel), were compared to examine the role of a slightly different chemical…”
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Effects of caffeine and paracetamol alone or in combination with acetylsalicylic acid on prostaglandin E 2 synthesis in rat microglial cells by Fiebich, B.L., Lieb, K., Hüll, M., Aicher, B., van Ryn, J., Pairet, M., Engelhardt, G.

“…Paracetamol has mild analgesic and antipyretic properties and is, along with acetylsalicylic acid, one of the most popular “over the counter” analgesic agents…”
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Clinical experience with cyclooxygenase-2 inhibitors by van Ryn, J, Pairet, M

“…Increasing amounts of experimental and clinical data support the role of selective cyclooxygenase (COX)-2 inhibition in anti-inflammatory processes and the…”
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Effects of Telmisartan on Renal Excretory Function in Conscious Dogs by Schierok, H, Pairet, M, Hauel, N, Wienen, W

“…The present study investigated the effects of telmisartan, a selective AT1 receptor antagonist, on renal function in dogs. Conscious female dogs were treated…”
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Inhibition of Cyclooxygenase-1 and Cyclooxygenase-2 Analysis of In Vitro Test Systems and Their Clinical Relevance by Pairet, Michel

“…Numerous in vitro assay systems have been developed for testing and comparing the relative inhibitory activities of nonsteroidal anti-inflammatory drugs…”
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Differential inhibition of cyclooxygenase-1 (COX-1) and-2 (COX-2) by NSAIDS: Consequences on anti-inflammatory activity versus gastric and renal safety by Pairet, M., Churchill, L., Trummlitz, G., Engelhardt, G.

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Opioid receptor agonists in the rabbit colon: comparison of in vivo and in vitro studies by Pairet, M, Ruckebusch, Y

“…Myoelectrical activity was recorded in the proximal and distal colon of rabbits using chronically implanted electrodes. The motility in both the proximal and…”
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Opioid control of the ruminant stomach motility: functional importance of mu, kappa and delta receptors by Ruckebusch, Y, Bardon, T, Pairet, M

“…In sheep, the subcutaneous (SC) or intracerebroventricular (ICV) administration of the mu-type opioid agonists, fentanyl and morphine, evokes a blockade of the…”
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Colonic formation of soft feces in rabbits: a role for endogenous prostaglandins by Pairet, M, Bouyssou, T, Ruckebusch, Y

“…Rabbits produce hard and soft feces in a circadian rhythm. The motor activity of the haustrated proximal colon is inhibited during the formation of soft feces,…”
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Effects of intraluminal nutrients on intestinal myoelectric activity in rabbits by Bouyssou, T, Pairet, M, Candau, M, Ruckebusch, Y

“…In the unanesthetized rabbit, intraluminal infusions of D- and L-methionine, L-tryptophan, D-glucose, D-xylose, and lactulose had a biphasic effect on small…”
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COX-2 selectivity and inflammatory processes by van Ryn, J, Trummlitz, G, Pairet, M

“…Increasing amounts of experimental and clinical data support the role of selective cyclooxygenase (COX)-2 inhibition in anti-inflammatory processes and the…”
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Cholinergic modulation of the release of serotonin in the gastric interstitial fluid. An in vivo study in rabbits by Pairet, M, Meirieu, O, Bardon, T, Ruckebusch, Y

“…Dialysis fibers chronically implanted into the gastric submucosa of rabbits allowed us to simultaneously (a) collect an interstitial fluid dialysate in which…”
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Measurement of differential inhibition of COX-1 and COX-2 and the pharmacology of selective inhibitors by Pairet, M, van Ryn, J

“…Since the discovery of a second isoenzyme of cyclooxygenase (COX)-2, it has been hypothesized that the antiinflammatory effects of non-steroidal…”
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Local release of monoamines in the gastrointestinal tract: an in vivo study in rabbits by Meirieu, O, Pairet, M, Sutra, J F, Ruckebusch, M

“…Dialysis fibers chronically implanted into the gastric submucosa of rabbits allowed us to collect an interstitial fluid (I.S.F.) dialysate in which biogenic…”
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Meloxicam inhibits the growth of colorectal cancer cells by GOLDMAN, A. P, WILLIAMS, C. S, HONGMIAO SHENG, LAMPS, L. W, WILLIAMS, V. P, PAIRET, M, MORROW, J. D, DUBOIS, R. N

“…Cyclooxygenase-2 has been reported to play an important role in colorectal carcinogenesis. The effects of meloxicam (a COX-2 inhibitor) on the growth of two…”
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Duodenal bulb motor activity in sheep by Ruckebusch, Y, Pairet, M

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Pharmacologic Characterization of Meloxicam by Pairet, Michel

“…Meloxicam provides a case study in the evolution of the cyclooxygenase (COX) hypothesis. Meloxicam was initially characterized in standard animal models of…”
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