Search Results - "Paioni, Paolo"
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Swiss consensus recommendations on urinary tract infections in children
Published in European journal of pediatrics (01-03-2021)“…The kidneys and the urinary tract are a common source of infection in children of all ages, especially infants and young children. The main risk factors for…”
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Is breastfeeding an equipoise option in effectively treated HIV-infected mothers in a high-income setting?
Published in Swiss medical weekly (24-07-2018)“…Combined antiretroviral treatment (cART) has reduced mother-to-child transmission (MTCT) of the human immunodeficiency virus (HIV) to virtually zero in…”
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Pharmacometric in silico studies used to facilitate a national dose standardisation process in neonatology - application to amikacin
Published in Swiss medical weekly (08-04-2024)“…Pharmacometric in silico approaches are frequently applied to guide decisions concerning dosage regimes during the development of new medicines. We aimed to…”
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Impact of rapid enterovirus polymerase chain reaction testing on management of febrile young infants < 90 days of age with aseptic meningitis
Published in BMC pediatrics (16-04-2020)“…Diagnostic evaluation of febrile young infants is challenging. Empirical antimicrobial treatment is therefore common practice in this setting despite high…”
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Discordant Impact of HLA on Viral Replicative Capacity and Disease Progression in Pediatric and Adult HIV Infection
Published in PLoS pathogens (01-06-2015)“…HLA class I polymorphism has a major influence on adult HIV disease progression. An important mechanism mediating this effect is the impact on viral…”
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The influence of human genetic variation on Epstein–Barr virus sequence diversity
Published in Scientific reports (25-02-2021)“…Epstein–Barr virus (EBV) is one of the most common viruses latently infecting humans. Little is known about the impact of human genetic variation on the large…”
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Cohort profile: the Swiss Mother and Child HIV Cohort Study (MoCHiV)
Published in BMJ open (23-09-2024)“…Prospective, multicentric observational cohort study in Switzerland investigating measures to prevent mother-to-child transmission in pregnant women with HIV…”
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Pharmacogenetic Analysis of Voriconazole Treatment in Children
Published in Pharmaceutics (17-06-2022)“…Voriconazole is among the first-line antifungal drugs to treat invasive fungal infections in children and known for its pronounced inter- and intraindividual…”
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Swiss recommendations on perioperative antimicrobial prophylaxis in children
Published in Swiss medical weekly (28-09-2022)“…Infection following surgical procedures leads to significant morbidity and mortality in all age groups. Sterile techniques, antibiotic prophylaxis and improved…”
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Author Correction: The influence of human genetic variation on Epstein–Barr virus sequence diversity
Published in Scientific reports (20-04-2021)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Correction to: Swiss consensus recommendations on urinary tract infections in children
Published in European journal of pediatrics (01-03-2021)“…The article “Swiss consensus recommendations on urinary tract infections in children”…”
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12
Sex Differences in Antiretroviral Therapy Initiation in Pediatric HIV Infection
Published in PloS one (07-07-2015)“…The incidence and severity of infections in childhood is typically greater in males. The basis for these observed sex differences is not well understood, and…”
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SwissPedData: Standardising hospital records for the benefit of paediatric research
Published in Swiss medical weekly (20-12-2021)“…Improvement of paediatric healthcare is hampered by inefficient processes for generating new evidence. Clinical research often requires extra encounters with…”
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14
Nef-specific CD8+ T cell responses contribute to HIV-1 immune control
Published in PloS one (02-09-2013)“…Recent studies in the SIV-macaque model of HIV infection suggest that Nef-specific CD8+ T-cell responses may mediate highly effective immune control of…”
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Migrating a Well-Established Longitudinal Cohort Database From Oracle SQL to Research Electronic Data Entry (REDCap): Data Management Research and Design Study
Published in JMIR formative research (31-05-2023)“…Providing user-friendly electronic data collection tools for large multicenter studies is key for obtaining high-quality research data. Research Electronic…”
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SwissPKcdw – A clinical data warehouse for the optimization of pediatric dosing regimens
Published in CPT: pharmacometrics and systems pharmacology (01-12-2021)“…Clinical trials have been performed mainly in adults and accordingly the necessary information is lacking for pediatric patients, especially regarding dosage…”
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The rate of mother-to-child transmission of antiretroviral drug-resistant HIV strains is low in the Swiss Mother and Child HIV Cohort Study
Published in Swiss medical weekly (04-04-2019)“…Combination antiretroviral therapy (cART) has reduced mother-to-child transmissions (MTCT) and improved the prognosis of HIV-infected newborns. However, drug…”
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Gentamicin Population Pharmacokinetics in Pediatric Patients-A Prospective Study with Data Analysis Using the saemix Package in R
Published in Pharmaceutics (01-10-2021)“…The aminoglycoside gentamicin is used for the empirical treatment of pediatric infections. It has a narrow therapeutic window. In this prospective study at…”
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19
Co-operative additive effects between HLA alleles in control of HIV-1
Published in PloS one (19-10-2012)“…HLA class I genotype is a major determinant of the outcome of HIV infection, and the impact of certain alleles on HIV disease outcome is well studied. Recent…”
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Risk factors for central line–associated bloodstream infections in children with tunneled central venous catheters
Published in American journal of infection control (01-01-2020)“…•Gastrointestinal disease and 2 to 5 years of age are independent risk factors for central line–associated bloodstream infections (CLABSIs).•CLABSI risk…”
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