Search Results - "Paioni, P."

Trends in HCV treatment uptake, efficacy and impact on liver fibrosis in the Swiss HIV Cohort Study by Béguelin, Charles, Suter, Annatina, Bernasconi, Enos, Fehr, Jan, Kovari, Helen, Bucher, Heiner C., Stoeckle, Marcel, Cavassini, Mathias, Rougemont, Mathieu, Schmid, Patrick, Wandeler, Gilles, Rauch, Andri, Aubert, V, Battegay, M, Böni, J, Braun, DL, Calmy, A, Ciuffi, A, Dollenmaier, G, Egger, M, Elzi, L, Fellay, J, Furrer, H, Fux, CA, Günthard, HF, Haerry, D, Hasse, B, Hirsch, HH, Hoffmann, M, Hösli, I, Kahlert, C, Kaiser, L, Keiser, O, Klimkait, T, Kouyos, RD, Ledergerber, B, Martinetti, G, Tejada, B, Marzolini, C, Metzner, KJ, Müller, N, Nicca, D, Pantaleo, G, Paioni, P, Rudin, C, Scherrer, AU, Speck, R, Stöckle, M, Tarr, P, Trkola, A, Vernazza, P, Weber, R, Yerly, S

“…Background & Aims Hepatitis C virus (HCV) therapies with interferon‐free second‐generation direct‐acting antivirals (DAAs) are highly effective and well…”
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Weight and Metabolic Changes After Switching From Tenofovir Disoproxil Fumarate to Tenofovir Alafenamide in People Living With HIV : A Cohort Study by Surial, Bernard, Mugglin, Catrina, Calmy, Alexandra, Cavassini, Matthias, Günthard, Huldrych F, Stöckle, Marcel, Bernasconi, Enos, Schmid, Patrick, Tarr, Philip E, Furrer, Hansjakob, Ledergerber, Bruno, Wandeler, Gilles, Rauch, Andri

“…Tenofovir-based antiretroviral therapy (ART) has become first-line in all major HIV treatment guidelines. Compared with tenofovir disoproxil fumarate (TDF),…”
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Cohort Profile Update: The Swiss HIV Cohort Study (SHCS) by Scherrer, Alexandra U, Traytel, Anna, Braun, Dominique L, Calmy, Alexandra, Battegay, Manuel, Cavassini, Matthias, Furrer, Hansjakob, Schmid, Patrick, Bernasconi, Enos, Stoeckle, Marcel, Kahlert, Christian, Trkola, Alexandra, Kouyos, Roger D, Tarr, Philip, Marzolini, Catia, Wandeler, Gilles, Fellay, Jacques, Bucher, Heiner, Yerly, Sabine, Suter, Franziska, Hirsch, Hans, Huber, Michael, Dollenmaier, Günter, Perreau, Matthieu, Martinetti, Gladys, Rauch, Andri, Günthard, Huldrych F

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Adverse events of raltegravir and dolutegravir by Elzi, Luigia, Erb, Stefan, Furrer, Hansjakob, Cavassini, Matthias, Calmy, Alexandra, Vernazza, Pietro, Günthard, Huldrych, Bernasconi, Enos, Battegay, Manuel

“…To compare the frequency and risk factors of toxicity-related treatment discontinuations between raltegravir and dolutegravir. Prospective cohort study. All…”
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P73 Paediatric population pharmacokinetic modeling for gentamicin – is the current dose recommendation justified? by Paioni, P, Berger, C, Krämer, SD

“…BackgroundMonitoring of gentamicin serum trough level (Cmin) is standard practice in children to prevent toxicity by accumulation1. Cmin < 2 mg/L are…”
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Impact of Integrase Inhibitors on Cardiovascular Disease Events in People With Human Immunodeficiency Virus Starting Antiretroviral Therapy by Surial, Bernard, Chammartin, Frédérique, Damas, José, Calmy, Alexandra, Haerry, David, Stöckle, Marcel, Schmid, Patrick, Bernasconi, Enos, Fux, Christoph A, Tarr, Philip E, Günthard, Huldrych F, Wandeler, Gilles, Rauch, Andri

“…Abstract Background Integrase strand transfer inhibitors (INSTIs) have been associated with an increased risk for cardiovascular disease (CVD) events. We…”
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Time Trends in Causes of Death in People With HIV: Insights From the Swiss HIV Cohort Study by Weber, M S R, Duran Ramirez, J J, Hentzien, M, Cavassini, M, Bernasconi, E, Hofmann, E, Furrer, H, Kovari, H, Stöckle, M, Schmid, P, Haerry, D, Braun, D L, Günthard, H F, Kusejko, K

“…Abstract Background Advancements in access to antiretroviral therapy (ART) and human immunodeficiency virus (HIV) care have led to a decline in AIDS-related…”
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Sustained Effect on Hepatitis C Elimination Among Men Who Have Sex With Men in the Swiss HIV Cohort Study: A Systematic Re-Screening for Hepatitis C RNA Two Years Following a Nation-Wide Elimination Program by Kusejko, Katharina, Salazar-Vizcaya, Luisa, Shah, Cyril, Stöckle, Marcel, Béguelin, Charles, Schmid, Patrick, Ongaro, Marie, Darling, Katherine, Bernasconi, Enos, Rauch, Andri, Kouyos, Roger D, Günthard, Huldrych F, Böni, Jürg, Fehr, Jan S, Braun, Dominique L

“…Abstract Background The Swiss HCVree Trial (NCT 02785666) was conducted in 2015–2017 with the goal of implementing a population-based systematic hepatitis C…”
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Prevalence of HIV-1 drug resistance mutations in proviral DNA in the Swiss HIV Cohort Study, a retrospective study from 1995 to 2018 by Jaha, Bashkim, Schenkel, Corinne D, Jörimann, Lisa, Huber, Michael, Zaheri, Maryam, Neumann, Kathrin, Leemann, Christine, Calmy, Alexandra, Cavassini, Matthias, Kouyos, Roger D, Günthard, Huldrych F, Metzner, Karin J

“…Abstract Background Genotypic resistance testing (GRT) is routinely performed upon diagnosis of HIV-1 infection or during virological failure using plasma…”
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Transfer of antiretroviral drugs into breastmilk: a prospective study from the Swiss Mother and Child HIV Cohort Study by Aebi-Popp, Karoline, Kahlert, Christian R, Crisinel, Pierre-Alex, Decosterd, Laurent, Saldanha, Susana Alves, Hoesli, Irene, Martinez De Tejada, Begona, Duppenthaler, Andrea, Rauch, Andri, Marzolini, Catia

“…In 2018, Switzerland changed its guidelines to support women living with HIV wishing to breastfeed. The exposure of antiretroviral drugs (ARVs) in breastmilk…”
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Weight, Anthropometric and Metabolic Changes After Discontinuing Antiretroviral Therapy Containing Tenofovir Alafenamide (TAF) in People With Human Immunodeficiency Virus (HIV) by Damas, José, Munting, Aline, Fellay, Jacques, Haerry, David, Marzolini, Catia, Tarr, Philip E, Steffen, Ana, Braun, Dominique L, Stoeckle, Marcel, Bernasconi, Enos, Tshikung, Olivier Nawej, Fux, Christoph A, Darling, Katharine E A, Béguelin, Charles, Wandeler, Gilles, Cavassini, Matthias, Surial, Bernard, Abela, I, Aebi-Popp, K, Anagnostopoulos, A, Battegay, M, Bernasconi, E, Braun, D L, Bucher, H C, Calmy, A, Cavassini, M, Ciuffi, A, Dollenmaier, G, Egger, M, Elzi, L, Fehr, J, Fellay, J, Furrer, H, Fux, C A, Günthard, H F, Hachfeld, A, Haerry, D, Hasse, B, Hirsch, H H, Hoffmann, M, Hösli, I, Huber, M, Jackson-Perry, D, Kahlert, C R, Kaiser, L, Keiser, O, Klimkait, T, Kouyos, R D, Kovari, H, Kusejko, K, Labhardt, N, Leuzinger, K, Martinez de Tejada, B, Marzolini, C, Metzner, K J, Müller, N, Nemeth, J, Nicca, D, Notter, J, Paioni, P, Pantaleo, G, Perreau, M, Rauch, A, Salazar-Vizcaya, L, Schmid, P, Speck, R, Stöckle, M, Tarr, P, Trkola, A, Wandeler, G, Weisser, M, Yerly, S

“…Abstract Background Antiretroviral therapy (ART)-related weight gain is of particular concern in people with HIV (PWH). Although weight gain was observed among…”
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Chemsex drugs on the rise: a longitudinal analysis of the Swiss HIV Cohort Study from 2007 to 2017 by Hampel, B, Kusejko, K, Kouyos, RD, Böni, J, Flepp, M, Stöckle, M, Conen, A, Béguelin, C, Künzler‐Heule, P, Nicca, D, Schmidt, AJ, Nguyen, H, Delaloye, J, Rougemont, M, Bernasconi, E, Rauch, A, Günthard, HF, Braun, DL, Fehr, J, Anagnostopoulos, A., Battegay, M., Bucher, H. C., Calmy, A., Cavassini, M., Ciuffi, A., Dollenmaier, G., Egger, M., Elzi, L., Fellay, J., Furrer, H., Fux, C. A., Haerry, D., Hasse, B., Hirsch, H. H., Hoffmann, M., Hösli, I., Huber, M., Kahlert, C., Kaiser, L., Keiser, O., Klimkait, T., Kovari, H., Ledergerber, B., Martinetti, G., Martinez de Tejada, B., Marzolini, C., Metzner, K. J., Müller, N., Paioni, P., Pantaleo, G., Perreau, M., Rudin, C., Scherrer, A. U., Schmid, P., Speck, R., Tarr, P., Trkola, A., Vernazza, P., Wandeler, G., Weber, R., Yerly, S.

“…Objectives Chemsex refers to the use of sex‐enhancing drugs among men who have sex with men (MSM) in combination with specific sexual and social behaviours…”
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Circulating HBV RNA and Hepatitis B Core-Related Antigen Trajectories in Persons With HIV/HBV Coinfection and Hepatitis B Surface Antigen Loss During Tenofovir Therapy by Begré, Lorin, Boyd, Anders, Plissonnier, Marie-Laure, Testoni, Barbara, Salazar-Vizcaya, Luisa, Suter-Riniker, Franziska, Scholtès, Caroline, Béguelin, Charles, Rockstroh, Jürgen K, Günthard, Huldrych F, Calmy, Alexandra, Cavassini, Matthias, Hirsch, Hans H, Schmid, Patrick, Bernasconi, Enos, Levrero, Massimo, Wandeler, Gilles, Zoulim, Fabien, Rauch, Andri

“…We evaluated long-term trajectories of circulating hepatitis B virus (HBV) RNA and hepatitis B core-related antigen (HBcrAg) in persons with and without…”
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Population pharmacokinetics of unbound and total dolutegravir concentrations in children aged 12 years and older: a PK substudy of the SMILE trial by Abdalla, Seef, Compagnucci, Alexandra, Zheng, Yi, Tréluyer, Jean-Marc, Saidi, Yacine, Ramos, José T, Coelho, Alexandra, Riault, Yoann, Cressey, Tim R, Hirt, Déborah

“…SMILE, a multicentre randomized trial, compared the efficacy and safety of switching virologically suppressed children and adolescents with HIV to a once-daily…”
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Deciphering Factors Linked With Reduced Severe Acute Respiratory Syndrome Coronavirus 2 Susceptibility in the Swiss HIV Cohort Study by Abela, Irene A, Hauser, Anthony, Schwarzmüller, Magdalena, Pasin, Chloé, Kusejko, Katharina, Epp, Selina, Cavassini, Matthias, Battegay, Manuel, Rauch, Andri, Calmy, Alexandra, Notter, Julia, Bernasconi, Enos, Fux, Christoph A, Leuzinger, Karoline, Perreau, Matthieu, Ramette, Alban, Gottschalk, Jochen, Schindler, Eméry, Wepf, Alexander, Marconato, Maddalena, Manz, Markus G, Frey, Beat M, Braun, Dominique L, Huber, Michael, Günthard, Huldrych F, Trkola, Alexandra, Kouyos, Roger D

“…Abstract Background Factors influencing susceptibility to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remain to be resolved. Using data from…”
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Polygenic Risk Scores for Prediction of Subclinical Coronary Artery Disease in Persons With Human Immunodeficiency Virus (HIV): The Swiss HIV Cohort Study by Schoepf, Isabella C, Thorball, Christian W, Kovari, Helen, Ledergerber, Bruno, Buechel, Ronny R, Calmy, Alexandra, Weber, Rainer, Kaufmann, Philipp A, Nkoulou, René, Schwenke, Johannes M, Braun, Dominique L, Fellay, Jacques, Tarr, Philip E

“…In people with human immunodeficiency virus (HIV) (PWH), individual polygenic risk scores (PRSs) are associated with coronary artery disease (CAD) events…”
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Population Pharmacokinetics of Cabotegravir Following Oral Administration and Long‐Acting Intramuscular Injection in Real‐World People with HIV by Thoueille, Paul, Saldanha, Susana Alves, Schaller, Fabian, Choong, Eva, Veuve, François, Munting, Aline, Cavassini, Matthias, Braun, Dominique, Günthard, Huldrych F., Duran Ramirez, Jessy J., Surial, Bernard, Furrer, Hansjakob, Rauch, Andri, Ustero, Pilar, Calmy, Alexandra, Stöckle, Marcel, Di Benedetto, Caroline, Bernasconi, Enos, Schmid, Patrick, Marzolini, Catia, Girardin, François R., Buclin, Thierry, Decosterd, Laurent A., Guidi, Monia, Abela, I, Aebi‐Popp, K, Anagnostopoulos, A, Battegay, M, Bernasconi, E, Braun, DL, Bucher, HC, Calmy, A, Cavassini, M, Ciuffi, A, Dollenmaier, G, Egger, M, Elzi, L, Fehr, J, Fellay, J, Furrer, H, Fux, CA, Günthard, HF, Hachfeld, A, Haerry, D, Hasse, B, Hirsch, HH, Hoffmann, M, Hösli, I, Huber, M, Jackson‐Perry, D, Kahlert, CR, Kaiser, L, Keiser, O, Klimkait, T, Kouyos, RD, Kovari, H, Kusejko, K, Labhardt, N, Leuzinger, K, Martinez de Tejada, B, Marzolini, C, Metzner, KJ, Müller, N, Nemeth, J, Nicca, D, Notter, J, Paioni, P, Pantaleo, G, Perreau, M, Rauch, A, Salazar‐Vizcaya, L, Schmid, P, Speck, R, Stöckle, M, Tarr, P, Trkola, A, Wandeler, G, Weisser, M, Yerly, S.

“…Long‐acting cabotegravir has been studied mainly in the stringent framework of clinical trials, which does not necessarily reflect the situation of people with…”
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Phylogenetic Cluster Analysis Identifies Virological and Behavioral Drivers of Human Immunodeficiency Virus Transmission in Men Who Have Sex With Men by Bachmann, Nadine, Kusejko, Katharina, Nguyen, Huyen, Chaudron, Sandra E, Kadelka, Claus, Turk, Teja, Böni, Jürg, Perreau, Matthieu, Klimkait, Thomas, Yerly, Sabine, Battegay, Manuel, Rauch, Andri, Ramette, Alban, Vernazza, Pietro, Bernasconi, Enos, Cavassini, Matthias, Günthard, Huldrych F, Kouyos, Roger D, Anagnostopoulos, A, Battegay, M, Bernasconi, E, Böni, J, Braun, D L, Bucher, H C, Calmy, A, Cavassini, M, Ciuffi, A, Dollenmaier, G, Egger, M, Elzi, L, Fehr, J, Fellay, J, Furrer, H, Fux, C A, Günthard, H F, Haerry, D, Hasse, B, Hirsch, H H, Hoffmann, M, Hösli, I, Huber, M, Kahlert, C R, Kaiser, L, Keiser, O, Klimkait, T, Kouyos, R D, Kovari, H, Ledergerber, B, Martinetti, G, Martinez de Tejada, B, Marzolini, C, Metzner, K J, Müller, N, Nicca, D, Paioni, P, Pantaleo, G, Perreau, M, Rauch, A, Rudin, C, Scherrer, A U, Schmid, P, Speck, R, Stöckle, M, Tarr, P, Trkola, A, Vernazza, P, Wandeler, G, Weber, R, Yerly, S

“…Abstract Background Identifying local outbreaks and their drivers is a key step toward curbing human immunodeficiency virus (HIV) transmission and potentially…”
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Impact of Latent Tuberculosis on Diabetes by Tepekule, Burcu, Kusejko, Katharina, Zeeb, Marius, Tarr, Philip E, Calmy, Alexandra, Battegay, Manuel, Furrer, Hansjakob, Cavassini, Matthias, Bernasconi, Enos, Notter, Julia, Günthard, Huldrych F, Nemeth, Johannes, Kouyos, Roger D

“…While an increased risk of active and latent tuberculosis infection (LTBI) in people with type-2 diabetes (DM) has been demonstrated, it is less well…”
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High Rates of Subsequent Asymptomatic Sexually Transmitted Infections and Risky Sexual Behavior in Patients Initially Presenting With Primary Human Immunodeficiency Virus-1 Infection by Braun, Dominique L, Marzel, Alex, Steffens, Daniela, Schreiber, Peter W, Grube, Christina, Scherrer, Alexandra U, Kouyos, Roger D, Günthard, Huldrych F

“…Knowledge of the risk factors of individuals with an asymptomatic sexually transmitted infection (STI) is essential for implementation of targeted STI…”
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