Search Results - "Painter, Meghan M."

Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) by Atagi, Yuka, Liu, Chia-Chen, Painter, Meghan M., Chen, Xiao-Fen, Verbeeck, Christophe, Zheng, Honghua, Li, Xia, Rademakers, Rosa, Kang, Silvia S., Xu, Huaxi, Younkin, Steven, Das, Pritam, Fryer, John D., Bu, Guojun

“…Several heterozygous missense mutations in the triggering receptor expressed on myeloid cells 2 (TREM2) have recently been linked to risk for a number of…”
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Apolipoprotein E4 Impairs Neuronal Insulin Signaling by Trapping Insulin Receptor in the Endosomes by Zhao, Na, Liu, Chia-Chen, Van Ingelgom, Alexandra J., Martens, Yuka A., Linares, Cynthia, Knight, Joshua A., Painter, Meghan M., Sullivan, Patrick M., Bu, Guojun

“…Diabetes and impaired brain insulin signaling are linked to the pathogenesis of Alzheimer’s disease (AD). The association between diabetes and AD-associated…”
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Apolipoprotein E as a Therapeutic Target in Alzheimer’s Disease: A Review of Basic Research and Clinical Evidence by Yamazaki, Yu, Painter, Meghan M., Bu, Guojun, Kanekiyo, Takahisa

“…Alzheimer’s disease (AD) is a devastating neurodegenerative disorder that causes progressive cognitive decline. The majority of AD cases are sporadic and…”
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TREM2 in CNS homeostasis and neurodegenerative disease by Painter, Meghan M, Atagi, Yuka, Liu, Chia-Chen, Rademakers, Rosa, Xu, Huaxi, Fryer, John D, Bu, Guojun

“…Myeloid-lineage cells accomplish a myriad of homeostatic tasks including the recognition of pathogens, regulation of the inflammatory milieu, and mediation of…”
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Antidepressants at environmentally relevant concentrations affect predator avoidance behavior of larval fathead minnows (Pimephales promelas) by Painter, Meghan M, Buerkley, Megan A, Julius, Matthew L, Vajda, Alan M, Norris, David O, Barber, Larry B, Furlong, Edward T, Schultz, Melissa M, Schoenfuss, Heiko L

“…The effects of embryonic and larval exposure to environmentally relevant (ng/L) concentrations of common antidepressants, fluoxetine, sertraline, venlafaxine,…”
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Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer’s disease by Shinohara, Mitsuru, Murray, Melissa E., Frank, Ryan D., Shinohara, Motoko, DeTure, Michael, Yamazaki, Yu, Tachibana, Masaya, Atagi, Yuka, Davis, Mary D., Liu, Chia-Chen, Zhao, Na, Painter, Meghan M., Petersen, Ronald C., Fryer, John D., Crook, Julia E., Dickson, Dennis W., Bu, Guojun, Kanekiyo, Takahisa

“…Cerebral amyloid angiopathy (CAA) often coexists with Alzheimer’s disease (AD). APOE4 is a strong genetic risk factor for both AD and CAA. Sex-dependent…”
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Antiviral Protection via RdRP-Mediated Stable Activation of Innate Immunity by Painter, Meghan M, Morrison, James H, Zoecklein, Laurie J, Rinkoski, Tommy A, Watzlawik, Jens O, Papke, Louisa M, Warrington, Arthur E, Bieber, Allan J, Matchett, William E, Turkowski, Kari L, Poeschla, Eric M, Rodriguez, Moses

“…For many emerging and re-emerging infectious diseases, definitive solutions via sterilizing adaptive immunity may require years or decades to develop, if they…”
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Abbreviated exposure to hypoxia is sufficient to induce CNS dysmyelination, modulate spinal motor neuron composition, and impair motor development in neonatal mice by Watzlawik, Jens O, Kahoud, Robert J, O'Toole, Ryan J, White, Katherine A M, Ogden, Alyssa R, Painter, Meghan M, Wootla, Bharath, Papke, Louisa M, Denic, Aleksandar, Weimer, Jill M, Carey, William A, Rodriguez, Moses

“…Neonatal white matter injury (nWMI) is an increasingly common cause of cerebral palsy that results predominantly from hypoxic injury to progenitor cells…”
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Selective uptake and biological consequences of environmentally relevant antidepressant pharmaceutical exposures on male fathead minnows by Schultz, Melissa M., Painter, Meghan M., Bartell, Stephen E., Logue, Amanda, Furlong, Edward T., Werner, Stephen L., Schoenfuss, Heiko L.

“…Antidepressant pharmaceuticals have been reported in wastewater effluent at the nanogram to low microgram-per-liter range, and include bupropion (BUP),…”
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Polysialic acid as an antigen for monoclonal antibody HIgM12 to treat multiple sclerosis and other neurodegenerative disorders by Watzlawik, Jens O., Kahoud, Robert J., Ng, Shermayne, Painter, Meghan M., Papke, Louisa M., Zoecklein, Laurie, Wootla, Bharath, Warrington, Arthur E., Carey, William A., Rodriguez, Moses

“…CNS regeneration is a desirable goal for diseases of brain and spinal cord. Current therapeutic strategies for the treatment of multiple sclerosis (MS) aim to…”
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Cellular targets and mechanistic strategies of remyelination-promoting IgMs as part of the naturally occurring autoantibody repertoire by Watzlawik, Jens O, Wootla, Bharath, Painter, Meghan M, Warrington, Arthur E, Rodriguez, Moses

“…Immunoglobulins with germline sequences occur in invertebrates and vertebrates and are named naturally occurring autoantibodies (NAbs). NAbs may target foreign…”
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Antibody Binding Specificity for Kappa (Vκ) Light Chain-containing Human (IgM) Antibodies: Polysialic Acid (PSA) Attached to NCAM as a Case Study by Watzlawik, Jens O, Kahoud, Robert J, Wootla, Bharath, Painter, Meghan M, Warrington, Arthur E, Carey, William A, Rodriguez, Moses

“…Antibodies of the IgM isotype are often neglected as potential therapeutics in human trials, animal models of human diseases as well as detecting agents in…”
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Polysialic acid as an antigen for monoclonal antibody HI gM12 to treat multiple sclerosis and other neurodegenerative disorders by Watzlawik, Jens O., Kahoud, Robert J., Ng, Shermayne, Painter, Meghan M., Papke, Louisa M., Zoecklein, Laurie, Wootla, Bharath, Warrington, Arthur E., Carey, William A., Rodriguez, Moses

“…Abstract CNS regeneration is a desirable goal for diseases of brain and spinal cord. Current therapeutic strategies for the treatment of multiple sclerosis (…”
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Antiviral Protection via RdRP-Mediated Stable Activation of Innate Immunity: e1005311 by Painter, Meghan M, Morrison, James H, Zoecklein, Laurie J, Rinkoski, Tommy A, Watzlawik, Jens O, Papke, Louisa M, Warrington, Arthur E, Bieber, Allan J, Matchett, William E, Turkowski, Kari L, Poeschla, Eric M, Rodriguez, Moses

“…For many emerging and re-emerging infectious diseases, definitive solutions via sterilizing adaptive immunity may require years or decades to develop, if they…”
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Antibody Binding Specificity for Kappa (Vκ) Light Chain-containing Human (IgM) Antibodies: Polysialic Acid (PSA) Attached to NCAM as a Case Study by Watzlawik, Jens O., Kahoud, Robert J., Wootla, Bharath, Painter, Meghan M., Warrington, Arthur E., Carey, William A., Rodriguez, Moses

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Antiviral Protection via RdRP-Mediatedy Stable Activation of Innate Immunit by Painter, Meghan M

“…All RNA viruses encode RNA-dependent RNA polymerases (RdRPs) which produce viral replication intermediates that trigger acute innate immune activation through…”
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Abbreviated Exposure to Hypoxia Is Sufficient to Induce CNS Dysmyelination, Modulate Spinal Motor Neuron Composition, and Impair Motor Development in Neonatal Mice: e0128007 by Watzlawik, Jens O, Kahoud, Robert J, O'Toole, Ryan J, White, Katherine AM, Ogden, Alyssa R, Painter, Meghan M, Wootla, Bharath, Papke, Louisa M, Denic, Aleksandar, Weimer, Jill M

“…Neonatal white matter injury (nWMI) is an increasingly common cause of cerebral palsy that results predominantly from hypoxic injury to progenitor cells…”
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