Search Results - "Paine McCullough, Michele"
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Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans
Published in Science (American Association for the Advancement of Science) (04-09-2020)“…Coronavirus disease 2019 (COVID-19) represents a global crisis, yet major knowledge gaps remain about human immunity to severe acute respiratory syndrome…”
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Antibiotics-Driven Gut Microbiome Perturbation Alters Immunity to Vaccines in Humans
Published in Cell (05-09-2019)“…Emerging evidence indicates a central role for the microbiome in immunity. However, causal evidence in humans is sparse. Here, we administered broad-spectrum…”
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Immunologic mechanisms of seasonal influenza vaccination administered by microneedle patch from a randomized phase I trial
Published in npj vaccines (14-07-2021)“…In a phase 1 randomized, single-center clinical trial, inactivated influenza virus vaccine delivered through dissolvable microneedle patches (MNPs) was found…”
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Durability of mRNA-1273 vaccine-induced antibodies against SARS-CoV-2 variants
Published in Science (American Association for the Advancement of Science) (17-09-2021)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mutations may diminish vaccine-induced protective immune responses, particularly as antibody…”
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Transcriptomic Biomarkers Associated with Microbiological Etiology and Disease Severity in Childhood Pneumonia
Published in The Journal of infectious diseases (14-10-2024)“…Challenges remain in discerning microbiologic etiology and disease severity in childhood pneumonia. Defining host transcriptomic profiles during illness may…”
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Daily fosfomycin versus levofloxacin for complicated urinary tract infections
Published in mBio (31-10-2023)“…Concerns over resistance and safety have been identified in the current treatment regimen for complicated urinary tract infections. Fosfomycin is a drug that…”
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