Search Results - "Paim, Gisele R."
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Antinociceptive effect of 3-(4-fluorophenyl)-5-trifluoromethyl-1H-1-tosylpyrazole. A Celecoxib structural analog in models of pathological pain
Published in Pharmacology, biochemistry and behavior (01-09-2014)“…Pain is the most common complaint in the medical field and the identification of novel compounds that can effectively treat painful states without causing side…”
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Facile Synthesis and Structural Characterization by NMR, ESI-MS/MS and DFT Calculations of New (E)-6-[2-Ferrocenylalkylidenehydrazino]nicotinic Hydrazides and Their (E)-Ferrocenyl-pyrazolyl-pyridine Heterocyclic System
Published in Journal of heterocyclic chemistry (01-09-2014)“…This paper reports a facile and convenient access by a conventional thermal procedure in ethanol as solvent to a new examples of…”
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Chemoselective fluorination of 2-hydroxy-3,4,7,8-tetrahydro-2H-chromen-5(6H)-ones using DAST
Published in Tetrahedron letters (29-06-2011)“…In this study, diethylaminosulfur trifluoride (DAST) was successfully applied in monofluorination reactions of some trifluoromethyl substituted…”
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General method for dehydration, intramolecular cyclization, and fluorination of trifluoromethyl-1H-pyrazoles using DAST
Published in Tetrahedron letters (21-07-2010)Get full text
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New trifluoromethyl-containing (E)-N′-arylidene-[3-alkyl(aryl/heteroaryl)-4,5-dihydro-1H-pyrazol-1-yl]carbohydrazides: Synthesis, crystal structure and antimicrobial/antioxidant activity
Published in Journal of fluorine chemistry (01-03-2012)“…The regioselective synthesis and structural study via X-ray diffraction of a series of twenty-seven new…”
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DAST promotes the synthesis of new 5-(trifluoromethyl)-3-(1,1-difluoroethan-2-yl)-1H-pyrazoles
Published in Tetrahedron letters (01-04-2009)Get full text
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The first application of 4-alkoxy-1,1,1-trifluoroalk-3-en-2-ones in a three-component condensation protocol for the synthesis of 3-acyl-4-aryl-2-(trifluoromethyl)-2-hydroxy-3,4,7,8-tetrahydro-2H-chromen-5(6H)-ones
Published in Journal of fluorine chemistry (01-03-2011)“…The one-pot three-component condensation protocol for the preparation of a new series of…”
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General method for dehydration, intramolecular cyclization, and fluorination of trifluoromethyl-1 H-pyrazoles using DAST
Published in Tetrahedron letters (2010)“…In this study, the versatile diethylaminosulfur trifluoride (DAST), a well-known fluorinating agent, was applied in the dehydration, intramolecular…”
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DAST promotes the synthesis of new 5-(trifluoromethyl)-3-(1,1-difluoroethan-2-yl)-1 H-pyrazoles
Published in Tetrahedron letters (2009)“…This study describes, firstly, the synthesis of a new precursor, 4,6,6-trimethoxy-1,1,1-trifluorohex-3-en-2-one ( 1), from the trifluoroacetylation reaction of…”
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The first application of 4-alkoxy-1,1,1-trifluoroalk-3-en-2-ones in a three-component condensation protocol for the synthesis of 3-acyl-4-aryl-2-(trifluoromethyl)-2-hydroxy-3,4,7,8-tetrahydro-2H- c hromen-5(6H)-ones
Published in Journal of fluorine chemistry (01-01-2011)“…The one-pot, simple and efficient three-component condensation protocol for the preparation of a series of twenty-five new…”
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6-Hydrazinonicotinic acid hydrazide: an useful precursor for chemo- and regioselective synthesis of new heteroaryl-linked pyridinohydrazones
Published in ARKIVOC (27-07-2012)Get full text
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New succinyl-spaced pyrazoles: Regioselective synthesis of 1,4-bis[5-(trichloromethyl)-1H-pyrazol-1-yl]butane-1,4-diones
Published in Journal of heterocyclic chemistry (01-01-2011)“…The facile and convenient access by a conventional procedure in ethanol as solvent to a new series of succinyl‐spaced pyrazoles including…”
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Synthesis of new trihalomethylated and non-symmetrical substituted 2-(1H-pyrazolyl)-5-(1H-pyrazolylcarbonyl)pyridines
Published in Journal of the Brazilian Chemical Society (2009)“…This paper describes the synthesis of a new series of 2-[3-alkyl(aryl/heteroaryl)-…”
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