Search Results - "Paik, Kumnan"

The Receptor Binding Site of Human Interleukin-3 Defined by Mutagenesis and Molecular Modeling by Klein, Barbara K., Feng, Yiqing, McWherter, Charles A., Hood, William F., Paik, Kumnan, McKearn, John P.

“…Interleukin-3 (IL-3) is a member of the cytokine superfamily that promotes multi-potential hematopoietic cell growth by interacting with a cell surface…”
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Saturation Mutagenesis of Human Interleukin-3 (∗) by Olins, Peter O., Bauer, S. Christopher, Braford-Goldberg, Sarah, Sterbenz, Kris, Polazzi, Joseph O., Caparon, Maire H., Klein, Barbara K., Easton, Alan M., Paik, Kumnan, Klover, Jon A., Thiele, Barrett R., McKearn, John P.

“…A deletion variant of human interleukin-3, hIL-315-125, was produced in the periplasmic space of Escherichia coli and had full activity in an AML193.1.3 cell…”
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Circular Permutation of the Granulocyte Colony-Stimulating Factor Receptor Agonist Domain of Myelopoietin by McWherter, Charles A, Feng, Yiqing, Zurfluh, Linda L, Klein, Barbara K, Baganoff, Mark P, Polazzi, Joseph O, Hood, William F, Paik, Kumnan, Abegg, Ann L, Grabbe, Edith S, Shieh, Jeng-Jong, Donnelly, Ann M, McKearn, John P

“…Myelopoietins (MPOs) are a family of engineered dual interleukin-3 (IL-3) and granulocyte colony-stimulating factor (G-CSF) receptor agonists that are superior…”
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Potent Interleukin 3 Receptor Agonist with Selectively Enhanced Hematopoietic Activity Relative to Recombinant Human Interleukin 3 by Thomas, John W., Baum, Charles M., Hood, William F., Klein, Barbara, Monahan, Joseph B., Paik, Kumnan, Staten, Nicholas, Abrams, Mark, McKearn, John P.

“…A systematic evaluation of structure-activity information led to the construction of genetically engineered interleukin 3 (IL-3) receptor agonists…”
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Use of combinatorial mutagenesis to select for multiply substituted human interleukin-3 variants with improved pharmacologic properties by Klein, Barbara K., Olins, Peter O., Bauer, S.Christopher, Caparon, Maire H., Easton, Alan M., Braford, Sarah R., Abrams, Mark A., Klover, Jon A., Paik, Kumnan, Thomas, John W., Hood, William F., Shieh, Jeng-Jong, Polazzi, Joseph O., Donnelly, Ann M., Zeng, David L., Welply, Joseph K., McKearn, John P.

“…A combinatorial mutagenesis strategy was used to create a collection of nearly 500 variants of human interleukin 3 (IL-3), each with four to nine amino acid…”
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Rapid Changes in Synaptic Vesicle Cytochemistry after Depolarization of Cultured Cholinergic Sympathetic Neurons by Johnson, Mary I., Paik, Kumnan, Higgins, Dennis

“…Sympathetic neurons taken from rat superior cervical ganglia and grown in culture acquire cholinergic function under certain conditions. These cholinergic…”
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