Search Results - "Paige, Ellie"
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A cross-platform approach identifies genetic regulators of human metabolism and health
Published in Nature genetics (01-01-2021)“…In cross-platform analyses of 174 metabolites, we identify 499 associations ( P < 4.9 × 10 −10 ) characterized by pleiotropy, allelic heterogeneity, large and…”
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Cardiovascular disease subtypes, physical disability and workforce participation: A cross-sectional study of 163,562 middle-aged Australians
Published in PloS one (08-04-2021)“…Workforce participation is reduced among people with cardiovascular disease (CVD). However, detailed quantitative evidence on this is limited. We examined the…”
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Observed and predicted premature mortality in Australia due to non-communicable diseases: a population-based study examining progress towards the WHO 25X25 goal
Published in BMC medicine (10-02-2022)“…The World Health Organization's (WHO) 25X25 goal aims for a 25% relative reduction in premature death due to four non-communicable diseases (NCD4)-cancer,…”
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The potential for current sodium and potassium production to support a global switch to the use of potassium-enriched salt: a desktop research study
Published in Public health nutrition (22-04-2024)“…Switching regular salt (sodium chloride) to salt enriched with potassium chloride (25 % potassium chloride, 75 % sodium chloride) has been shown to reduce…”
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Prioritising cardiovascular disease risk assessment to high risk individuals based on primary care records
Published in PloS one (29-09-2023)“…To provide quantitative evidence for systematically prioritising individuals for full formal cardiovascular disease (CVD) risk assessment using primary care…”
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Comparison of cardiovascular disease risk factors, assessment and management in men and women, including consideration of absolute risk: a nationally representative cross-sectional study
Published in BMJ open (22-12-2020)“…ObjectivesCardiovascular disease (CVD) is highly preventable and optimal treatments based on absolute risk can halve risk of future events. Compared with…”
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Factors related to under‐treatment of secondary cardiovascular risk, including primary healthcare: Australian National Health Survey linked data analysis
Published in Australian and New Zealand journal of public health (01-08-2022)“…To inform national evidence gaps on cardiovascular disease (CVD) preventive medication use and factors relating to under‐treatment ‐ including primary…”
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Neutrophil-mediated IL-6 receptor trans-signaling and the risk of chronic obstructive pulmonary disease and asthma
Published in Human molecular genetics (15-04-2017)“…The Asp358Ala variant in the interleukin-6 receptor (IL-6R) gene has been implicated in asthma, autoimmune and cardiovascular disorders, but its role in other…”
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Income-related inequalities in chronic conditions, physical functioning and psychological distress among older people in Australia: cross-sectional findings from the 45 and up study
Published in BMC public health (22-07-2014)“…The burden of chronic disease continues to rise as populations age. There is relatively little published on the socioeconomic distribution of this burden in…”
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The 45 and Up Study: reflecting on contributions to global evidence using case studies on cardiovascular disease and smoking
Published in Public Health Research & Practice (01-12-2022)“…To describe the attributes that have underscored the success of the 45 and Up Study (the Study) and demonstrate its value by reflecting on two case studies:…”
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Using Polygenic Risk Scores for Prioritizing Individuals at Greatest Need of a Cardiovascular Disease Risk Assessment
Published in Journal of the American Heart Association (01-08-2023)“…Background The aim of this study was to provide quantitative evidence of the use of polygenic risk scores for systematically identifying individuals for…”
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The relationship between body mass index and hospitalisation rates, days in hospital and costs: findings from a large prospective linked data study
Published in PloS one (04-03-2015)“…Internationally there is limited empirical evidence on the impact of overweight and obesity on health service use and costs. We estimate the burden of…”
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Education-related variation in coronary procedure rates and the contribution of private health care in Australia: a prospective cohort study
Published in International journal for equity in health (14-08-2020)“…Contemporary Australian evidence on socioeconomic variation in secondary cardiovascular disease (CVD) care, a possible contributor to inequalities in…”
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Differences between men and women in the use of preventive medications following a major cardiovascular event: Australian prospective cohort study
Published in Preventive medicine reports (01-06-2021)“…•Use of preventive medications following a major CVD event was sub-optimal.•Use of preventive medications was lower in women vs men at 3 months after CVD…”
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Aboriginal and Torres Strait Islander health checks: sociodemographic characteristics and cardiovascular risk factors
Published in Public Health Research & Practice (01-03-2022)“…To quantify Aboriginal and Torres Strait Islander health check claims in Australian adults in relation to sociodemographic and health characteristics,…”
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Socioeconomic factors, medication subsidisation and the use of preventative cardiovascular disease medications in Australia
Published in International journal of population data science (25-08-2022)“…ObjectivesCardiovascular disease (CVD) events are highly preventable through appropriate treatment and disproportionally affect socioeconomically disadvantaged…”
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Demonstrating the Utility of New Linked National Health Survey and Administrative Data: Secondary CVD Prevention in The Community
Published in International journal of population data science (07-12-2020)“…IntroductionCardiovascular events are largely preventable though access to timely quality primary health care and use of guideline-recommended medication…”
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Interleukin-6 Receptor Signaling and Abdominal Aortic Aneurysm Growth Rates
Published in Circulation. Genomic and precision medicine (01-02-2019)“…The Asp358Ala variant (rs2228145; A>C) in the IL (interleukin)-6 receptor ( IL6R) gene has been implicated in the development of abdominal aortic aneurysms…”
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A record linkage of antidepressant medication use and weight change in Australian adults
Published in Australian and New Zealand journal of psychiatry (01-11-2015)“…Explores the connection between the use of antidepressants and weight gain taking into account the type, dose, duration used and how recently they were taken…”
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