Search Results - "Paidakula, Suresh"

One-Pot Multi-Component Synthesis and Biological Evaluation of Novel Indole-Pyrimidine Derivatives as Potent Anti-Cancer and Anti-Microbial Agents by Juluru Bhaskar, Srinivas, Bandari, Gouthami, Dasari, Suresh, Paidakula

“…A series of novel hybrids of indole-pyrimidine moieties were synthesized and evaluated for their in vitro anti-cancer, in vitro anti-bacteria and in vitro…”
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Recent Trends in Tubulin-Binding Combretastatin A-4 Analogs for Anticancer Drug Development by Paidakula, Suresh, Nerella, Srinivas, Kankala, Shravankumar, Kankala, Ranjith Kumar

“…Although significant progress over several decades has been evidenced in cancer therapy, there remains a need for the development of novel and effective…”
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Design and synthesis of 4β-Acetamidobenzofuranone-podophyllotoxin hybrids and their anti-cancer evaluation by Paidakula, Suresh, Nerella, Srinivas, Vadde, Ravinder, Kamal, Ahmed, Kankala, Shravankumar

“…[Display omitted] A new series of amide derivatives of 4β-Acetamidobenzofuranone-podophyllotoxin hybrids (14a–g) were synthesized and their chemical structures…”
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Synthesis of d-ring modified acid hydrazide derivatives of podophyllotoxin and their anticancer studies as Tubulin inhibiting agents by Nerella, Srinivas, Kankala, Shravankumar, Paidakula, Suresh, Gavaji, Brahmeshwari

“…[Display omitted] •d-ring modified Podophyllic Acid hydrazides were successfully synthesized.•Among synthesized compounds, 3c and 3f have shown potential…”
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One-pot synthesis of some new regioselective 4β-pyrazolepodophyllotoxins as DNA topoisomerase-II targeting anticancer agents by Nagavath, Rajkumar, Nukala, Satheesh Kumar, Sirassu, Narsimha, Sagam, Ravikumar Reddy, Manchal, Ravinder, Paidakula, Suresh, Thirukovela, Narasimha Swamy

“…•Simple, efficient and recyclable PdNPs catalytic system for the one-pot synthesis of new 4β-pyrazolepodophsyllotoxins (6a-6o) in benign H2O/PEG-400.•Compounds…”
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Hydrophilic Pd-phosphines catalyzed one-pot synthesis of substituted isoquinolines, furopyridines and thienopyridines in aqueous medium by Guguloth, Veeranna, Thirukovela, Narasimha Swamy, Balaboina, Ramesh, Paidakula, Suresh, Vadde, Ravinder

“…[Display omitted] •Hydrophilic Pd-phosphine/CuI catalysed one-pot three component approach.•Synthesis of isoquinolines, furopyridines and thienopyridines in…”
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AgI‐promoted one‐pot synthesis of aminoindolizines via sequential Mannich‐Grignard addition and intramolecular cyclization in water by Guguloth, Veeranna, Balaboina, Ramesh, Paidakula, Suresh, Thirukovela, Narasimha S., Vadde, Ravinder

“…The efficient synthesis of aminoindolizines in ecofriendly water with broad substrate scope from the mild and readily available AgI‐catalyzed one‐pot…”
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Design and Synthesis of Some Novel Aromatic Amide Derivatives of Nilutamide as In Vitro Anticancer Agents by Thirukovela, Narasimha Swamy, Nukala, Satheesh Kumar, Sirassu, Narsimha, Manchal, Ravinder, Gundepaka, Prasad, Paidakula, Suresh

“…The synthesis of some new aromatic amide derivatives of Nilutamide (4 a–n) and their structure determination using 1H NMR, 13C NMR and mass spectral analysis…”
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Anticancer Evaluation of Some New 4β‐Imidazolopodophyllotoxin ‐Aromatic Amides by Nagavath, Rajkumar, Nukala, Satheesh Kumar, Sagam, Ravikumar Reddy, Sirassu, Narsimha, Guguloth, Veeranna, Kamarajugadda, Pavan, Paidakula, Suresh, Thirukovela, Narasimha Swamy

“…Herein, we described the synthesis of some new aromatic amides of 4β‐imidazolopodophyllotoxin (6 a–p) and their anticancer evaluation against four human cancer…”
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Synthesis of a new 4-aza-2,3-didehydropodophyllotoxin analogues as potent cytotoxic and antimitotic agents by Kamal, Ahmed, Suresh, Paidakula, Mallareddy, Adla, Kumar, Banala Ashwini, Reddy, Papagari Venkat, Raju, Paidakula, Tamboli, Jaki R., Shaik, Thokhir B., Jain, Nishant, Kalivendi, Shasi V.

“…A series of novel conjugates of 4-aza-2,3-didehydropodophyllotoxins ( 11a– w) were synthesized by a straightforward one-step multicomponent synthesis that…”
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An efficient one-pot synthesis of benzothiazolo-4β-anilino-podophyllotoxin congeners: DNA topoisomerase-II inhibition and anticancer activity by Kamal, Ahmed, Kumar, B. Ashwini, Suresh, Paidakula, Shankaraiah, Nagula, Kumar, M. Shiva

“…A facile one-pot zirconium tetrachloride and sodium iodide mediated iodination protocol has been applied for the synthesis of…”
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Synthesis and biological evaluation of 4-aza-2,3-dihydropyridophenanthrolines as tubulin polymerization inhibitors by Kamal, Ahmed, Srinivasa Reddy, T, Polepalli, Sowjanya, Paidakula, Suresh, Srinivasulu, Vunnam, Ganga Reddy, V, Jain, Nishant, Shankaraiah, Nagula

“…A series of novel 4-aza-2,3-dihydropyridophenanthrolines 12(a-t) were synthesized by a one-step three component condensation of 1,10-phenanthroline amine,…”
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4 beta -[4'-(1-(Aryl)ureido)benzamide]podophyllotoxins as DNA topoisomerase I and II alpha inhibitors and apoptosis inducing agents by Kamal, Ahmed, Suresh, Paidakula, Ramaiah, MJanaki, Reddy, TSrinivasa, Kapavarapu, Ravi Kumar, Rao, Bolla Narasimha, Imthiajali, Syed, Reddy, TLakshminarayan, Pushpavalli, SNCVL, Shankaraiah, Nagula, Pal-Bhadra, Manika

“…A series of 4 beta -[4'-(1-(aryl)ureido)benzamide]podophyllotoxin congeners (11a-l) were synthesized and evaluated for their cytotoxic activity against six…”
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4β-[4′-(1-(Aryl)ureido)benzamide]podophyllotoxins as DNA topoisomerase I and IIα inhibitors and apoptosis inducing agents by Kamal, Ahmed, Suresh, Paidakula, Ramaiah, M. Janaki, Srinivasa Reddy, T., Kapavarapu, Ravi Kumar, Rao, Bolla Narasimha, Imthiajali, Syed, Lakshminarayan Reddy, T., Pushpavalli, S.N.C.V.L., Shankaraiah, Nagula, Pal-Bhadra, Manika

“…A series of new 4β-[4′-(1-(aryl)urea)benzamido]podophyllotoxin congeners (11a–l) were synthesized and evaluated for their in vitro anticancer activity against…”
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Synthesis of 4β-carbamoyl epipodophyllotoxins as potential antitumour agents by Kamal, Ahmed, Ashwini Kumar, B., Suresh, Paidakula, Juvekar, Aarti, Zingde, Surekha

“…A series of new 4β-carbamoyl epipodophyllotoxin analogues have been synthesized and evaluated for their anticancer activity against eleven cancer cell lines…”
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Synthesis of chalcone-amidobenzothiazole conjugates as antimitotic and apoptotic inducing agents by Kamal, Ahmed, Mallareddy, Adla, Suresh, Paidakula, Shaik, Thokhir B., Lakshma Nayak, V., Kishor, Chandan, Shetti, Rajesh V.C.R.N.C., Sankara Rao, N., Tamboli, Jaki R., Ramakrishna, S., Addlagatta, Anthony

“…A series of chalcone-amidobenzothiazole conjugates (9a–k and 10a,b) have been synthesized and evaluated for their anticancer activity. All these compounds…”
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Regioselective synthesis of some new 1,4-disubstituted sulfonyl-1,2,3-triazoles and their antibacterial activity studies by Thirukovela, Narasimha Swamy, Kankala, Shravankumar, Kankala, Ranjith Kumar, Paidakula, Suresh, Gangula, Mohan Rao, Vasam, Chandra Sekhar, Vadde, Ravinder

“…Some new 1,4-disubstituted-sulfonyl-1,2,3-triazoles ( 3a – f , 5a – h , 7a – d , and 9a – e ) were regioselectively synthesized in high yields by Cu(I)…”
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Synthesis and anticancer activity of 4β-alkylamidochalcone and 4β-cinnamido linked podophyllotoxins as apoptotic inducing agents by Kamal, Ahmed, Mallareddy, Adla, Suresh, Paidakula, Lakshma Nayak, V., Shetti, Rajesh V.C.R.N.C., Sankara Rao, N., Tamboli, Jaki R., Shaik, Thokhir B., Vishnuvardhan, M.V.P.S., Ramakrishna, S.

“…A series of 4β-alkylamidochalcone and 4β-cinnamido linked podophyllotoxin congeners have been synthesized. All the twenty nine compounds were evaluated for…”
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Synthesis and biological evaluation of combretastatin-amidobenzothiazole conjugates as potential anticancer agents by Kamal, Ahmed, Mallareddy, Adla, Janaki Ramaiah, M., Pushpavalli, S.N.C.V.L., Suresh, Paidakula, Kishor, Chandan, Murty, J.N.S.R.C., Rao, N. Sankara, Ghosh, Sowjanya, Addlagatta, Anthony, Pal-Bhadra, Manika

“…A series of combretastatin-amidobenzothiazole conjugates have been synthesized and evaluated for their anticancer activity. All these compounds exhibited…”
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Synthesis of 4β- N-polyaromatic substituted podophyllotoxins: DNA topoisomerase inhibition, anticancer and apoptosis-inducing activities by Kamal, Ahmed, Kumar, B. Ashwini, Suresh, Paidakula, Agrawal, Satyam Kumar, Chashoo, Gousia, Singh, Shashank K., Saxena, A.K.

“…A new class of 4β- N-polyaromatic substituted podophyllotoxin congeners have been synthesized and evaluated for their DNA topoisomerase-II (topo-II) inhibition…”
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