Search Results - "Pai, Shweta G"

Notch signaling pathway targeted therapy suppresses tumor progression and metastatic spread in pancreatic cancer by Yabuuchi, Shinichi, Pai, Shweta G, Campbell, Nathaniel R, de Wilde, Roeland F, De Oliveira, Elizabeth, Korangath, Preethi, Streppel, Mirte M, Rasheed, Zeshaan A, Hidalgo, Manuel, Maitra, Anirban, Rajeshkumar, N.V

“…Highlights ► Pancreatic cancer is a devastating disease with an extremely poor life expectancy. ► We investigated the efficacy of Notch signaling pathway…”
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Treatment of Pancreatic Cancer Patient-Derived Xenograft Panel with Metabolic Inhibitors Reveals Efficacy of Phenformin by Rajeshkumar, N V, Yabuuchi, Shinichi, Pai, Shweta G, De Oliveira, Elizabeth, Kamphorst, Jurre J, Rabinowitz, Joshua D, Tejero, Héctor, Al-Shahrour, Fátima, Hidalgo, Manuel, Maitra, Anirban, Dang, Chi V

“…To identify effective metabolic inhibitors to suppress the aggressive growth of pancreatic ductal adenocarcinoma (PDAC), we explored the antitumor efficacy of…”
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Superior therapeutic efficacy of nab-paclitaxel over cremophor-based paclitaxel in locally advanced and metastatic models of human pancreatic cancer by Rajeshkumar, N V, Yabuuchi, Shinichi, Pai, Shweta G, Tong, Zeen, Hou, Shihe, Bateman, Scott, Pierce, Daniel W, Heise, Carla, Von Hoff, Daniel D, Maitra, Anirban, Hidalgo, Manuel

“…Background: Albumin-bound paclitaxel ( nab -paclitaxel, nab- PTX) plus gemcitabine (GEM) combination has demonstrated efficient antitumour activity and…”
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Abstract LB-94: Highlights of innovative preclinical studies which guided the rapid bench to bedside development of nab-paclitaxel plus gemcitabine combination for the treatment of pancreatic cancer by Rajeshkumar, N.V, Yabuuchi, Shinichi, Pai, Shweta G., Bateman, Scott, Filvaroff, Ellen, Pierce, Daniel W., Heise, Carla, Hoff, Daniel D. Von, Maitra, Anirban, Hidalgo, Manuel

“…Abstract Background and Aim: Advanced pancreatic cancer is both deadly and difficult to treat with success. Here, we disseminate the results of comprehensive…”
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Abstract 5396: Targeting multiple components of the mammalian target of rapamycin (mTOR) signaling: A novel combination therapy to improve pancreatic cancer treatment by Rajeshkumar, N.V, Yabuuchi, Shinichi, Patel, Chirag, Pai, Shweta G., Le, Dung T., Von Hoff, Daniel D., Dang, Chi V., Maitra, Anirban, Powell, Jonathan

“…Abstract Background and Aim: Pancreatic ductal adenocarcinoma remains a lethal malignancy with historically limited success in treatment. This study aims to…”
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