Search Results - "Pai, Priya"

Multiple roles of HOX proteins in Metastasis: Let me count the ways by Jonkers, Joy, Pai, Priya, Sukumar, Saraswati

“…Knowledge of the role of HOX proteins in cancer has been steadily accumulating in the last 25 years. They are encoded by 39 HOX genes arranged in 4 distinct…”
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Pediatric trauma in the rural and low resourced communities by Pai, Priya K., Klinkner, Denise B.

“…Death and disability associated with traumatic injury can be significantly decreased with timely and appropriate care. Patients in rural areas tend to have…”
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Guggulsterone decreases proliferation and metastatic behavior of pancreatic cancer cells by modulating JAK/STAT and Src/FAK signaling by Macha, Muzafar A, Rachagani, Satyanarayana, Gupta, Suprit, Pai, Priya, Ponnusamy, Moorthy P, Batra, Surinder K, Jain, Maneesh

“…Highlights • Guggulsterone (GS) decreased growth and colony formation of pancreatic cancer (PC) cells. • GS treatment induced apoptosis and cell cycle arrest…”
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MicroRNAs (miRNAs) as biomarker(s) for prognosis and diagnosis of gastrointestinal (GI) cancers by Macha, Muzafar A, Seshacharyulu, Parthasarathy, Krishn, Shiv Ram, Pai, Priya, Rachagani, Satyanarayana, Jain, Maneesh, Batra, Surinder K

“…Gastrointestinal (GI) cancers remain one of the most common malignancies and are the second common cause of cancer deaths worldwide. The limited effectiveness…”
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Prospects of miRNA-based therapy for pancreatic cancer by Pai, Priya, Rachagani, Satyanarayana, Are, Chandrakanth, Batra, Surinder K

“…Pancreatic cancer (PC) is the fourth leading cause of cancer related deaths in the U.S., with a less than 6% five-year survival rate. Treatment is confounded…”
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MUC4 overexpression augments cell migration and metastasis through EGFR family proteins in triple negative breast cancer cells by Mukhopadhyay, Partha, Lakshmanan, Imayavaramban, Ponnusamy, Moorthy P, Chakraborty, Subhankar, Jain, Maneesh, Pai, Priya, Smith, Lynette M, Lele, Subodh M, Batra, Surinder K

“…Current studies indicate that triple negative breast cancer (TNBC), an aggressive breast cancer subtype, is associated with poor prognosis and an early pattern…”
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Chylolymphatic mesenteric cyst with midgut volvulus in an adolescent: a peculiar presentation by Pai, Priya K., Gudmundsdottir, Hallbera, Hull, Nathan C., Thacker, Paul G., Klinkner, Denise B.

“…Mesenteric cysts are rare intra-abdominal masses in the pediatric population, with the chylolymphatic variant comprising only 7.3% of all abdominal cysts…”
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Altered Biochemical Parameters in Saliva of Pediatric Attention Deficit Hyperactivity Disorder by Archana, E., Pai, Priya, Prabhu, Bhavya K., Shenoy, Revathi P., Prabhu, Krishnananda, Rao, Anjali

“…Oxidative stress is one of the common causes in etiopathogenesis of attention deficit hyperactivity disorder (ADHD). Hence, the salivary levels of protein…”
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Mucins and associated O-glycans based immunoprofile for stratification of colorectal polyps: clinical implication for improved colon surveillance by Krishn, Shiv Ram, Kaur, Sukhwinder, Sheinin, Yuri M, Smith, Lynette M, Gautam, Shailendra K, Patel, Asish, Jain, Maneesh, Juvvigunta, Vasthala, Pai, Priya, Lazenby, Audrey J, Roy, Hemant K, Batra, Surinder K

“…Sessile serrated adenoma/polyps (SSA/P) are premalignant lesions of colorectal cancer that are difficult to distinguish histologically from hyperplastic polyps…”
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HOX genes and the NF-κB pathway: A convergence of developmental biology, inflammation and cancer biology by Pai, Priya, Sukumar, Saraswati

“…The roles of HOX transcription factors as oncogenes and tumor suppressor genes, and the NF-KB pathway in chronic inflammation, both leading to cancer are…”
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Changes in microRNA (miRNA) expression during pancreatic cancer development and progression in a genetically engineered KrasG12D;Pdx1-Cre mouse (KC) model by Rachagani, Satyanarayana, Macha, Muzafar A, Menning, Melanie S, Dey, Parama, Pai, Priya, Smith, Lynette M, Mo, Yin-Yuan, Batra, Surinder K

“…Differential expression of microRNAs (miRNAs) has been demonstrated in various cancers, including pancreatic cancer (PC). Due to the lack of tissue samples…”
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Abstract 4467: The role of HOXA5 in the malignant progression of engineered isogenic MCF10A sublines harboring common breast cancer mutations by Pai, Priya, Wang, Guannan, Sukumar, Saraswati

“…Abstract Background and Aims: HOXA5 behaves as a tumor suppressor gene in breast cancer and regulates E-cadherin, CD24, progesterone receptor and p53. Retinoic…”
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Mucins and Wnt/β-catenin signaling in gastrointestinal cancers: an unholy nexus by Pai, Priya, Rachagani, Satyanarayana, Dhawan, Punita, Batra, Surinder K

“…The Wnt/β-catenin signaling pathway is indispensable for embryonic development, maintenance of adult tissue homeostasis and repair of epithelial injury…”
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Intraductal administration of transferrin receptor-targeted immunotoxin clears ductal carcinoma in situ in mouse models of breast cancer-a preclinical study by Wang, Guannan, Kumar, Alok, Ding, Wanjun, Korangath, Preethi, Bera, Tapan, Wei, Junxia, Pai, Priya, Gabrielson, Kathleen, Pastan, Ira, Sukumar, Saraswati

“…The human transferrin receptor (TFR) is overexpressed in most breast cancers, including preneoplastic ductal carcinoma in situ (DCIS). HB21(Fv)-PE40 is a…”
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Abstract P5-08-03: Intraductal administration of a Transferrin Receptor-directed immunotoxin eliminates ductal carcinoma in situ in preclinical mammary in-duct (MIND) models of breast cancer by Sukumar, Saraswati, Wang, Guannan, Kumar, Alok, Ding, Wanjun, Korangath, Preethi, Pai, Priya, Gabrielson, Kathleen, Pastan, Ira

“…Abstract Background: Increased detection of ductal carcinoma in situ (DCIS) has been a consequence of mammographic screening. Currently there is a reappraisal…”
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Comparing weight loss outcomes after conversion to Roux-en-Y gastric bypass versus duodenal switch from sleeve gastrectomy in a community hospital by Jen, Jeremy, Phan, Hau, Johnson, Brett, Blyn, Corliann, Lavrich, Janet, Mallem, Krishna, Pai, Priya Kalsank, Krecioch, Piotr

“…Background Recidivism after initial sleeve gastrectomy (SG) remains common. Revisional surgery to convert SG to Roux-en-Y gastric bypass (RYGB) or duodenal…”
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HOXA5-Mediated Stabilization of IκBα Inhibits the NF-κB Pathway and Suppresses Malignant Transformation of Breast Epithelial Cells by Pai, Priya, Wang, Guannan, Teo, Wei Wen, Raez-Rodriguez, Diana, Gabrielson, Kathleen L, Győrffy, Balázs, Downs, Bradley M, Aggarwal, Akanksha, Sukumar, Saraswati

“…HOXA5 is a transcription factor and tumor suppressor that promotes differentiation of breast epithelial cells and is frequently lost during malignant…”
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Intraductal fulvestrant for therapy of ERα-positive ductal carcinoma in situ of the breast: a preclinical study by Wang, Guannan, Chen, Chuang, Pai, Priya, Korangath, Preethi, Sun, Shengrong, Merino, Vanessa F, Yuan, Jingping, Li, Suping, Nie, Guangjun, Stearns, Vered, Sukumar, Saraswati

“…Mammographic screening for breast cancer has led to increased detection of ductal carcinoma in situ (DCIS) and a reappraisal of the necessity of aggressive…”
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Mechanistic and Functional Shades of Mucins and Associated Glycans in Colon Cancer by Pothuraju, Ramesh, Krishn, Shiv Ram, Gautam, Shailendra K, Pai, Priya, Ganguly, Koelina, Chaudhary, Sanjib, Rachagani, Satyanarayana, Kaur, Sukhwinder, Batra, Surinder K

“…Mucus serves as the chief protective barrier against pathogenic and mechanical insults in respiratory, gastrointestinal, and urogenital tracts. Altered mucin…”
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Abstract 3475: Suppression of inflammatory signaling by HOXA5 via modulation of the NF-KB pathway in breast cancer by Pai, Priya, Wang, Guannan, Rodríguez, Diana Ráez, Yu, Wayne, Sukumar, Saraswati

“…Abstract Background and Aims: HOXA5 is a tumor suppressor in breast cancer (BC) and transcriptionally regulates E-cadherin, CD24, progesterone receptor and…”
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