Search Results - "Pai, Medha Gayathri J"
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Proteomics and Machine Learning Approaches Reveal a Set of Prognostic Markers for COVID-19 Severity With Drug Repurposing Potential
Published in Frontiers in physiology (27-04-2021)“…The pestilential pathogen SARS-CoV-2 has led to a seemingly ceaseless pandemic of COVID-19. The healthcare sector is under a tremendous burden, thus…”
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Multiple Reaction Monitoring-Based Targeted Assays for the Validation of Protein Biomarkers in Brain Tumors
Published in Frontiers in oncology (14-05-2021)“…The emergence of omics technologies over the last decade has helped in advancement of research and our understanding of complex diseases like brain cancers…”
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Proteomic investigation reveals dominant alterations of neutrophil degranulation and mRNA translation pathways in patients with COVID-19
Published in iScience (19-03-2021)“…The altered molecular proteins and pathways in response to COVID-19 infection are still unclear. Here, we performed a comprehensive proteomics-based…”
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Mass spectrometry and proteome analysis to identify SARS-CoV-2 protein from COVID-19 patient swab samples
Published in STAR protocols (18-03-2022)“…With new emerging SARS-CoV-2 strains and their increased pathogenicity, diagnosis has become more challenging. Molecular diagnosis often involves the use of…”
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A proteome-level view of brain tumors for a better understanding of novel diagnosis, prognosis, and therapy
Published in Expert review of proteomics (02-12-2023)“…Brain tumors are complex and heterogeneous malignancies with significant challenges in diagnosis, prognosis, and therapy. Proteomics, the large-scale study of…”
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A Multi-omics Longitudinal Study Reveals Alteration of the Leukocyte Activation Pathway in COVID-19 Patients
Published in Journal of proteome research (01-10-2021)“…Severe coronavirus disease 2019 (COVID-19) infection may lead to lung injury, multi-organ failure, and eventually death. Cytokine storm due to excess cytokine…”
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IL-17A Orchestrates Reactive Oxygen Species/HIF1α-Mediated Metabolic Reprogramming in Psoriasis
Published in The Journal of immunology (1950) (15-01-2024)“…Immune cell-derived IL-17A is one of the key pathogenic cytokines in psoriasis, an immunometabolic disorder. Although IL-17A is an established regulator of…”
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Proteomics analysis of differentially abundant proteins in the rohu kidney infected with Edwardsiella tarda
Published in Comparative biochemistry and physiology. Part D, Genomics & proteomics (01-06-2024)“…Edwardsiella tarda (Et) is a zoonotic gram-negative pathogen with a diverse host range, including fish. However, the in-depth molecular mechanisms underlying…”
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